Rectally. The suppository is released from the contoured package and then injected into the rectum. Preliminarily it is recommended to empty the intestine.
The dose and duration of the drug depends on the nature, severity and duration of the disease.
In acute infectious intestinal diseases, accompanied by diarrhea syndrome: the initial dose is 2 suppositories 50 mg once, then 1 suppository 2 times a day until the symptoms of intoxication stop. Perhaps the subsequent continuation of the course of 1 suppository with an interval of 72 hours. The course of 20 suppositories of 50 mg.
With gastric ulcer and 12 duodenal ulcer in an acute period: 2 days for 2 suppositories 1 time per day, then 1 suppository with an interval of 72 hours. Course 15-25 suppositories. In the chronic period: 5 days to 1 suppository once a day, then one every 72 hours. The course of 20 suppositories.
With viral hepatitis: the initial dose is 2 suppositories once, then one - 2 times a day until the symptoms of intoxication and inflammation stop. Subsequent continuation of the course on 1 suppository with an interval of 72 hours. The course of 20 suppositories.
With chronic recurrent diseases caused by the herpes virus: 1 suppository daily for 5 days, then one every other day - 15 suppositories.
In diseases caused by the papilloma virus: 5 days to 1 suppository once a day, then one suppository every other day. Course - 20 suppositories.
With purulent surgical diseases (burn lesions, recurrent furunculosis, chronic osteomyelitis, gangrenous appendicitis with omentitis, purulent pleurisy): 1 suppository daily-5 days, then 1 suppository every other day for 10 days.
With asthenic conditions, neurotic and somatoform disorders: 5 days, one suppository daily, then one every 72 hours. Course of 15 suppositories. To improve physical performance: 1 suppository every other day with a course of 5 suppositories.
For the prevention and treatment of surgical complications in the pre- and postoperative period (including cancer patients): prescribe 1 suppository 1 time per day - 5 suppositories before surgery, 5 - after surgery, one every other day and 5 suppositories - with an interval of 72 hours. In severe cases, the initial dose of 2 suppositories once or twice a day, one at a time. Course - 20 suppositories.
In the treatment and prevention of urogenital infections of bacterial and viral etiology: 1 day to 1 suppository 2 times a day, then 1 suppository every other day. The course of 10-15 suppositories (depending on the severity of the pathological process).
With inflammatory diseases of the mucous membrane of the oral cavity and throat, periodontal diseases: the initial dose of 1 suppository daily - 5 suppositories, then one at a time interval of 72 hours. Course of 15 suppositories.
With frequent recurrent diseases of the respiratory tract and ENT organs of bacterial and viral etiology (frequent ARI, bronchitis, pneumonia, chronic tonsillitis, chronic otitis media, chronic adenoiditis): one suppository daily for 5 days, then one suppository every other day for 10 days. Course of 15 suppositories.
For the prevention of influenza and acute respiratory infections one suppository once a day. Course 5 suppositories.