Active substanceAmino dihydrophthalazinedione sodiumAmino dihydrophthalazinedione sodium
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  • Galavit®
    suppositories rect. 
    SELVIM, LLC     Russia
  • Galavit®
    powder w / m 
    SELVIM, LLC     Russia
  • Galavit®
    pills n / az. 
    SELVIM, LLC     Russia
  • Dosage form: & nbspsublingual tablets
    Composition:Active substance - sodium aminodihydrophthalazinedione (Galavit®) 0.025 g, Excipients - sorbitol 0.315 g, starch 0.14 g, lactose 0.1 g, calcium stearate 0.005 g, talc 0.015 g and Racetenthol (Menthol) 0.0001 g.
    Description:Tablets white with a yellowish tinge, lenticular, without risks, with the smell of menthol.
    Pharmacotherapeutic group:Immunomodulating and anti-inflammatory agent
    ATX: & nbsp

    L.03   Immunostimulators

    Pharmacodynamics:

    The mechanism of action Galavita associated with the ability to influence the functional and metabolic activity of macrophages.

    In inflammatory diseases of the drug for 6-8 hours reversibly inhibits excessive synthesis of tumor necrosis factor, interleukin-1 and other pro-inflammatory cytokines, reactive oxygen species giperaktivirovannymi macrophages determining the degree of inflammatory reactions, their recurrence, as well as the severity of intoxication. The normalization of the functional state of the macrophages leads to the restoration of antigen-presenting and controlling functions, reduce the level of self-aggression.The drug stimulates the bactericidal activity of neutrophilic granulocytes, enhancing phagocytosis and increasing the nonspecific resistance of the organism to infectious diseases.

    Pharmacokinetics:

    It is excreted mainly through the kidneys. With sublingual use, the elimination half-life is 30 minutes. The main pharmacological effects are observed within 72 hours.

    Indications:

    As an immunomodulatory and anti-inflammatory agent in the complex therapy of immunodeficient conditions in adults and adolescents over 12 years of age:

    - infectious intestinal diseases, accompanied by intoxication and / or diarrhea;

    - Stomach ulcer and duodenal ulcer;

    - viral hepatitis;

    - chronic recurrent diseases caused by the herpes virus;

    - diseases caused by the human papillomavirus;

    - Infectious-inflammatory urogenital diseases (urethritis of chlamydial and trichomonas etiology, chlamydial prostatitis, acute and chronic salpingo-oophoritis, endometritis);

    - Pyoinflammatory diseases of the pelvic organs;

    - postoperative rehabilitation of patients with uterine myoma;

    - Complications of the postoperative period in women of reproductive age;

    - purulent surgical diseases (burn lesions, chronic osteomyelitis, gangrenous appendicitis with omentitis, peritonitis, purulent pleurisy);

    - postoperative purulent-septic complications and their prophylaxis (including in cancer patients);

    - chronic recurrent furunculosis, erysipelas;

    - asthenic conditions, neurotic and somatoform disorders, decrease in physical working capacity (including athletes); mental, behavioral and post-abstinence disorders in alcohol and drug dependence;

    - inflammatory diseases of the mucous membrane of the oral cavity and throat, periodontal disease;

    - frequent recurrent diseases of the respiratory tract and ENT organs of bacterial and viral etiology (frequent acute respiratory infections, bronchitis, pneumonia, chronic tonsillitis, chronic otitis media, chronic adenoiditis) and their prophylaxis.

    Contraindications:

    Individual intolerance; pregnancy and lactation.

    Dosing and Administration:

    Sublingually on the 1-st tablet daily up to 4 times a day or 2 tablets daily up to 2 times a day, depending on the diagnosis and severity of the disease.

    - In acute infectious intestinal diseases, accompanied by diarrhea syndrome: the initial dose is 2 tablets - once, then 1 tablet 3-4 times a day until the symptoms of intoxication stop within 3-5 days.

    - With stomach ulcer and 12 duodenal ulcer in acute period: The first 2 days to use 1 tablet 4 times a day, then every 3 days for 1 tablet 4 times a day, the course of 2-3 weeks. In the chronic period, apply: 5 days for 1 tablet 4 times a day, then every 3 days for 1 tablet 4 times a day for up to 3 weeks.

    - With viral hepatitis of different etiology: in the acute period of the disease, the initial dose is 2 tablets 2 times a day until the symptoms of intoxication and inflammation stop. Perhaps the subsequent continuation of the course of 1 tablet 4 times a day every 3 days for up to 2-3 weeks.

    - With chronic recurrent diseases caused by the herpes virus: 1 tablet 4 times a day for 10 days. Then 1 tablet 4 times a day every other day for 10 days.

    - For diseases caused by human papillomavirus: 5 days 1 tablet 4 times a day, then 1 tablet 4 times a day every other day, up to 2-3 weeks.

    - With urogenital diseases - urethritis chlamydial and trichomonas etiology, chlamydial prostatitis: the first day 2 times 2 tablets, then 1 tablet 4 times a day every other day, up to 2 weeks (depending on the severity of the pathological process).

    - With salpingo-oophoritis, endometrium: in the acute period of 2 days 2 tablets 2 times a day, then 1 tablet 4 times a day every 3 days for 3 weeks. In the chronic period - 5 days 1 tablet 4 times a day, then 1 tablet 4 times a day every 3 days, up to 2-3 weeks.

    - In acute and chronic purulent diseases of the pelvic organs: in the acute period - On the first day 2 tablets 2 times a day, then 3 days 1 tablet 4 times a day, then 1 tablet 4 times a day every other day for 10 days. In the chronic period - 5 days for 1 tablet 4 times a day, then 3-4 tablets every 3 days for up to 3 weeks.

    - For postoperative rehabilitation of patients with uterine myoma and with complications of the postoperative period in women of reproductive age: 5 days 1 tablet 4 times a day, then 1 tablet 4 times a day every other day up to 2 weeks.

    - In purulent surgical diseases (burn lesions, chronic osteomyelitis, gangrenous appendicitis with omentitis, peritonitis, purulent pleurisy): apply 4 times a day for 1 tablet for 5 days, then 1 tablet 4 times a day for up to 15 days.

    - For the prevention and treatment of surgical complications in the pre- and postoperative period (including cancer patients) prescribe 1 tablet 4 times a day for 5 days before surgery, 10 days after surgery 1 tablet 4 times every other day and for 3 weeks 1 tablet 4 times every 3 days. In severe course of the disease on the first day of 2 tablets 2 times a day.

    - With chronic recurrent furunculosis, erysipelas: 5 days 1 tablet 4 times a day, then 1 tablet 4 times a day, up to 3 weeks.

    - With asthenic conditions, neurotic and somatoform disorders, with mental, behavioral and post-abstinence disorders, in patients with alcohol and drug dependence: 5 days 1 tablet 4 times a day, then 1 tablet 4 times every 3 days for 3 weeks. To enhance physical working capacity: 1 tablet 4 times a day for 10 days, then 1 tablet 4 times a day 3 days up to 3 weeks.

    - With inflammatory diseases of the mucous membrane of the oral cavity and throat, periodontal diseases: the initial dose is 1 tablet 4 times a day for 5 days, then 1 tablet 4 times a day 3 days up to 3 weeks

    - With frequent recurrent diseases of the respiratory tract and ENT organs of bacterial and viral etiology (frequent acute respiratory infections, bronchitis, pneumonia, chronic tonsillitis, chronic otitis media, chronic adenoiditis): apply 4 times a day for 1 tablet for 5 days, then 1 tablet 4 times a day for up to 15 days. For the prevention of acute respiratory infections and influenza 1 tablet 2 times a day. Course 5-10 days.

    Side effects:In rare cases, allergic reactions are possible.
    Interaction:When simultaneous use of possible reduction in the course of antibiotics. Cases of incompatibility with other drugs have not been noted.
    Form release / dosage:Tablets containing 25 mg of Galavit®.
    Packaging:For 10 or 20 tablets of sublingual in a contiguous cell pack of a polyvinylchloride film and aluminum foil. For 1, 2, 3 or 4 contour packs together with instructions for use in a cardboard pack. 10, 20, 30, 40 or 50 contour packs with an equal number of instructions for use in a group package.
    Storage conditions:

    Store at a temperature of no higher than 25 ° C, protected from light, out of reach of children.

    Shelf life:

    3 years.

    Do not use after the expiration date indicated on the cardboard pack.

    Terms of leave from pharmacies:Without recipe
    Registration number:LSR-008746/09
    Date of registration:02.11.2009 / 26.09.2013
    Expiration Date:Unlimited
    The owner of the registration certificate:SELVIM, LLC SELVIM, LLC Russia
    Manufacturer: & nbsp
    Information update date: & nbsp12.03.2017
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