Combination drug for external use.
Hydrocortisone
By inhibition of phospholipase A activity2 and reducing the release of arachidonic acid from the phospholipids of cell membranes reduces the production of leukotrienes and prostaglandins. Due to this suppresses the development of inflammatory manifestations: pain, swelling, fever and redness in the area of inflammation. It inhibits the expression of the cyclooxygenase-2 gene, which also leads to inhibition of prostaglandin synthesis.
Reduces the main substance of the connective tissue, weakening the exudative and proliferative processes in the skin. Inhibits cellular kinins, which have proteolytic activity.Prevents the access of macrophages and T-sensitized lymphocytes to the foci of inflammation.
It has anti-inflammatory, anti-edematous and anti-allergic effect.
Oxytetracycline
Bacteriostatic of a wide spectrum of action. It is active against reproducing bacteria. Communicating with 30S-subunit of bacterial ribosomes, inhibits the synthesis of proteins of prokaryotes, suspending the process of elongation of the polypeptide chain.
It binds divalent ions to chelate complexes: calcium, magnesium, iron and zinc.
It is active against aerobic gram-positive bacteria: Streptococcus spp., Staphylococcus spp. (including strains producing penicillinase); Gram-negative bacteria: Bordetella pertussis, Neisseria gonorrhoeae, Escherichia coli, Enterobacter spp., Klebsiella spp., Shigella spp., Salmonella spp.; anaerobic bacteria: Clostridium spp., as well as in relation to Chlamydia spp., Mycoplasma spp., Spirochaetaceae, Rickettsia spp.