Active substanceMultivitamins + Other drugsMultivitamins + Other drugs
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  • Dosage form: & nbspcapsules
    Composition:

    1 capsule contains:

    active substances: thiamine hydrochloride (vitamin B1) 25 mg; riboflavin (vitamin B2) 25 mg; pyridoxine hydrochloride (vitamin B6) 25 mg; nicotinic acid (vitamin PP) 25 mg; calcium pantothenate (vitamin B3) 25 mg; folic acid (vitamin B9) 50 μg; cyanocobalamin (vitamin B12) 25 μg; nicotinoyl-gamma-aminobutyrate sodium (nicotinoyl-gamma-aminobutyric acid sodium salt) 50 mg;

    Excipients: povidone low molecular weight 2,505 mg; potato starch 44,9349 mg; sucrose (sugar) 177.4851 mg;

    composition of the capsule: dye quinoline yellow 0.9197%, dye "sunset sun" yellow 0.0044%, titanium dioxide 1.3333%, gelatin up to 100%.

    Description:

    Hard gelatin capsules number 0, body and lid yellow. Contents of capsules - a mixture of granules and a powder of yellow or orange-yellow color with white impregnations and characteristic odor, lumps are allowed.

    Pharmacotherapeutic group:Multivitamin + other preparations
    ATX: & nbsp

    A.11.A.B   Multivitamins in other combinations

    Pharmacodynamics:

    Combined drug containing a complex of vitamins and nicotinoyl-gamma-aminobutyric acid sodium salt, causing its influence on metabolic processes in the brain.

    The complex of vitamins that make up the drug contributes to the normalization of metabolism.

    Thiamine hydrochloride (vitamin B1) in the body is converted into coenzyme forms of enzymatic systems. It plays an important role in the carbohydrate, protein and fat metabolism, in the processes of conduction of nervous excitation in the synapses.

    Riboflavin (vitamin B2) interacts with adenosine triphosphoric acid, forming FMN and FAD - coenzymes of flavinproteins, thereby regulating the oxidation-reduction processes in the body; takes part in the transfer of hydrogen, carbohydrate, protein and fat metabolism, as well as in maintaining the normal visual function of the eye.

    Pyridoxine hydrochloride (vitamin B6) in the form of pyridoxal-5-phosphate is part of the enzymes that carry out decarboxylation and reamination of amino acids, plays an important role in the metabolism of tryptophan, methionine, cysteine, glutamic acid and other acids. Improves lipid metabolism in atherosclerosis, is necessary for the normal functioning of the central and peripheral nervous system.

    A nicotinic acid (vitamin PP) and its amide are prosthetic groups of NAD and NADPH enzymes, which are carriers of hydrogen and carry out oxidation-reduction processes.Has vasodilator and lipid-lowering effect.

    Calcium pantothenate (vitamin B3) as an integral part of coenzyme A plays an important role in the processes of acetylation and oxidation; participates in the synthesis of acetylcholine and the formation of corticosteroids.

    Folic acid (vitamin B9) in the body is restored to tetrahydrofolic acid, which is a coenzyme involved in various metabolic processes. Folic acid participates in the synthesis of amino acids, nucleotides and nucleic acids, is necessary for erythropoiesis.

    Cyanocobalamin (vitamin B12) participates in the transport of mobile methyl groups and hydrogen, is necessary for normal hematopoiesis. Participates in the synthesis of choline, methionine, creatine, nucleic acids, has a beneficial effect on the functions of the liver and nervous system.

    Included in the composition nicotinoyl-gamma-aminobutyric acid sodium salt (NAAMC) has a nootropic effect, dilates the vessels of the brain. It also has a tranquilizing, antiplatelet and antioxidant effect. Improves the functional state of the brain by influencing the cerebral circulation (increases the volume and linear velocitycerebral blood flow, reduces the resistance of cerebral vessels, improves microcirculation). At the course reception increases physical and mental efficiency, improves memory, normalizes sleep, relieves feelings of anxiety, tension and fear.

    Pharmacokinetics:

    The effect of the drug is determined by the combined effect of its components, therefore, it is not possible to carry out kinetic observations; all components can not be traced with the help of markers or bioassays.

    Indications:Deficiency of vitamins included in the composition of the drug.
    Contraindications:

    Children under 18 years of age are not recommended taking the drug.

    Increased individual sensitivity to the components of the drug, severe renal dysfunction, severe degree of acute impairment of cerebral circulation, sugar / isomaltase deficiency, fructose intolerance, glucose-galactose malabsorption.

    Pregnancy and lactation:

    The drug is contraindicated for use during pregnancy and during breastfeeding.

    Dosing and Administration:

    Gitagamp® is administered orally 1 capsule 2 times a day after meals in the morning and in the day, not later than 17 hours for 3-4 weeks.

    Side effects:

    Allergic reactions are possible (skin rash, itching). Dizziness, headache, mild nausea. In this case, you should reduce the dose or cancel the drug.

    If any of the above symptoms occur, consult a doctor immediately.

    Overdose:

    Overdose Symptoms: irritability, agitation, anxiety, dizziness, headache.

    If signs of an overdose stop taking the drug, see a doctor.

    Treatment symptomatic.

    Interaction:

    Biguanides reduce the absorption of vitamin B12.

    Fluorouracil, vinblastine, bleomycin, cisplatin disrupt the assimilation of vitamins B1, AT6.

    Penicillamine, isoniazid reduce the effectiveness of vitamin B1, increasing its excretion.

    Oral contraceptives (estrogens) reduce the concentration of folic acid.

    Vitamin B6 reduces the antiparkinsonian action of levopods, as well as the effects of steroid hormones.

    Isoniazid increases the excretion of vitamin B6 with urine and reduces its effectiveness.

    Cycloserine, hydralazine and penicillamine are antagonists of vitamin B6 .

    Special instructions:

    It is possible to stain the urine yellow.

    Effect on the ability to drive transp. cf. and fur:During the treatment period, care should be taken when driving vehicles and working with moving mechanisms.
    Form release / dosage:Capsules.
    Packaging:

    For 50 capsules in cans of polymeric with a lid with a control of the first opening or cans of polymeric with a screw cap, covered with a shrink film of PVC shrink.

    Each bank along with the instruction for use is placed in a pack of cardboard box.

    Storage conditions:

    Store in a dry, dark place at a temperature of no higher than 25 ° C.

    Keep out of the reach of children.

    Shelf life:

    3 years.

    Do not use after the expiration date indicated on the package.

    Terms of leave from pharmacies:Without recipe
    Registration number:P N001526 / 01
    Date of registration:09.02.2009 / 25.11.2014
    Expiration Date:Unlimited
    The owner of the registration certificate:ECHO NPK, Joint Stock Company ECHO NPK, Joint Stock Company Russia
    Manufacturer: & nbsp
    Information update date: & nbsp24.04.2017
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