Active substanceGlycineGlycine
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  • Dosage form: & nbsptablets cheek
    Composition:

    1 tablet cheek contains:

    active substance: glycine 250 mg.

    Excipients: aspartame 0.4 mg, copovidone 9.6 mg, magnesium stearate 2 mg, sorbitol 8 mg.

    Description:Tablets are white or almost white in color, round, biconvex, with a cross-shaped risk. Allowed a slight marbling.
    Pharmacotherapeutic group:Metabolic means
    ATX: & nbsp

    N.06.B.X   Other psychostimulants and nootropic drugs

    Pharmacodynamics:A replaceable amino acid, the central neurotransmitter of the inhibitory type of action. It improves the metabolic processes in the brain tissues, has an antidepressant and sedative effect. Has glycinergic and GABA-ergic, alpha1-adrenoblocking, antioxidant and antitoxic action; regulates the activity of glutamate (NMDA) receptors, due to which reduces psychoemotional tension, aggressiveness and conflict; improves social adaptation and mood; facilitates sleep and normalizes sleep; increases mental performance; reduces the severity of vegetative-vascular disorders (including the climacteric period) and cerebral disorders in ischemic stroke and craniocerebral trauma, the toxic effect of ethanol on the central nervous system.
    Pharmacokinetics:

    Easily penetrates into most biological fluids and body tissues, including the brain, not cumulates. Rapidly destroyed in the liver by glycine oxidase to water and carbon dioxide.

    Indications:Stress states (including psychoemotional stress), decreased mental performance, deviant forms of behavior of children and adolescents, various functional and organic diseases of the nervous system, accompanied by increased excitability, emotional instability, decreased mental performance and sleep disturbances: neuroses, neurosis-like conditions, consequences of neuroinfections and craniocerebral trauma, perinatal and other forms of encephalopathies (including alcoholic genesis).

    Ischemic stroke.

    In narcology - as a drug (LS), increasing mental performance and reducing psychoemotional stress during remission in cases of encephalopathy, organic lesions of the central and peripheral nervous system.

    Contraindications:Hypersensitivity.
    Carefully:Arterial hypotension.
    Pregnancy and lactation:

    The use of the drug is not recommended during pregnancy and during breastfeeding due to the lack of sufficient data on the safety of the drug during this period.

    Dosing and Administration:

    Sublingually or buccally 250 mg (in tablets or as a powder after grinding the tablet).

    Children, adolescents and adults with psychoemotional stresses, memory loss, attention, mental performance, mental retardation, with deviant forms of behavior glycine appointed by 1/2 tablets 2-3 times a day for 14-30 days.

    With functional and organic lesions of the nervous system, accompanied by increased excitability, emotional lability and sleep disturbance, children under 3 years of age are prescribed for 1/4 tablets 2-3 times a day for 7-14 days, later on 1/4 tablets once a day for 7-10 days. The daily dose is 100-150 mg, the course dose is 2-2.6 g. Children over 3 years and adults are prescribed for 1/2 tablets 2-3 times a day, the course of treatment - 7-14 days. It can be increased to 30 days. If necessary, the course is repeated after 30 days.

    If sleep disorders are prescribed 20 minutes before bedtime or just before bedtime, 1/4 -1/2 tablets (depending on age).

    In ischemic cerebral stroke: for the first 3-6 hours from the development of a stroke, 1 g (4 tablets) is given transbuccally or sublingually with 1 teaspoon of water, then for 1-5 days, 1 g / day (4 tablets), then during the next 30 days by 1/2 -1 tablet 3 times a day.

    In narcology - on 1/2 tablets 2-3 times a day for 14-30 days. If necessary, the courses are repeated 4-6 times a year.

    Side effects:

    Allergic reactions, drowsiness.

    Overdose:

    Cases of overdose are not described.

    Interaction:

    It reduces the severity of side effects of antipsychotic drugs (neuroleptics), anxiolytics, antidepressants, hypnotics and anticonvulsant drugs.

    Special instructions:

    In patients with a tendency to hypotension, the appointment is made in smaller doses and with the control of blood pressure.When it drops below the usual level, the reception stops.

    Effect on the ability to drive transp. cf. and fur:

    When taking the drug should be careful when driving vehicles and other potentially dangerous activities that require increased concentration and speed of psychomotor reactions.

    Form release / dosage:Bleaching tablets 250 mg.
    Packaging:

    For 10 or 30 tablets in a contour mesh box made of a transparent or white polyvinylchloride film and aluminum lacquered aluminum foil.

    According to 1, 2, 3, 5, 6, 9, 10 contour cell packs of 10 tablets or 1,2, 3 contour packs of 30 tablets together with instructions for use are placed in a pack of cardboard.

    Storage conditions:

    Store at a temperature of no higher than 25 ° C in the manufacturer's packaging. Keep out of the reach of children.

    Shelf life:

    3 years.

    Do not use after the expiration date.

    Terms of leave from pharmacies:On prescription
    Registration number:LSR-002849/09
    Date of registration:09.04.2009 / 17.05.2016
    Expiration Date:Unlimited
    The owner of the registration certificate:CANONFARMA PRODUCTION, CJSC CANONFARMA PRODUCTION, CJSC Russia
    Manufacturer: & nbsp
    Information update date: & nbsp01.05.2017
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