Active substanceGlycineGlycine
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  • Dosage form: & nbspsublingual tablets
    Composition:

    For 1 tablet:

    active substance: glycine 250.0 mg;

    Excipients: cellulose microcrystalline 134.0 mg, povidone (polyvinylpyrrolidone) 12.0 mg, magnesium stearate 4.0 mg.

    Description:

    Round, flat pills of white or almost white color with a cross-shaped risk on one side and chamfers on both sides. Allowed a slight marbling.

    Pharmacotherapeutic group:Metabolic means
    ATX: & nbsp

    N.06.B.X   Other psychostimulants and nootropic drugs

    Pharmacodynamics:A replaceable amino acid, the central neurotransmitter of the inhibitory type of action. Improves metabolic processes in brain tissues. Has antioxidant effect; regulates the activity of glutamate (NMDA) receptors, due to which reduces psychoemotional tension, aggressiveness and conflict; improves social adaptation and mood; facilitates sleep and normalizes sleep; increases mental performance; reduces the severity of vegetative-vascular disorders (including in the climacteric period) and cerebral disorders in ischemic stroke and head injury. Reduces the toxic effect of ethanol on the central nervous system.
    Pharmacokinetics:

    Easily penetrates into most biological fluids and body tissues, including the brain, not cumulates. Rapidly destroyed in the liver by glycine oxidase to water and carbon dioxide.

    Indications:

    Ischemic stroke.

    Contraindications:

    Hypersensitivity to glycine or to other components of the drug.

    Pregnancy and lactation.

    Carefully:Arterial hypotension.
    Pregnancy and lactation:

    The drug is contraindicated in pregnancy and during breastfeeding due to the lack of sufficient data on the safety of the drug during pregnancy and breastfeeding.

    Dosing and Administration:

    It is applied sublingually (under the tongue) or buccal (in tablets or as a powder after grinding the tablet).

    In adults with ischemic stroke: for the first 3-6 hours from the development of a stroke, 1 g (4 tablets) is given transbuccally or sublingually with 1 teaspoon of water, then for 1-5 days 1 g / day (4 tablets), then within the next 30 days for ½ - 1 tablet 3 times a day.

    Side effects:

    Allergic reactions, drowsiness.

    Overdose:

    Cases of overdose are not described.

    Interaction:

    Reduces the severity of side effects of antipsychotic drugs (neuroleptics), anxiolytics, antidepressants, hypnotics and anticonvulsants.

    Special instructions:

    Patients with a tendency to hypotension, the drug is used in smaller doses and under the control of blood pressure, when it drops below the usual level, the reception stops.

    Effect on the ability to drive transp. cf. and fur:

    When taking the drug should be careful when driving vehicles and other potentially dangerous activities that require increased concentration and speed of psychomotor reactions.

    Form release / dosage:

    Tablets are sublingual, 250.0 mg.

    Packaging:

    For 10, 25 tablets in a contour mesh box made of polyvinylchloride film and aluminum foil printed lacquered.

    For 10, 20, 30, 50, 60, 90 or 100 tablets in cans of polymeric for medicines.

    One jar or 1, 2, 3, 5, 9 or 10 contour squares, together with the instructions for use, are placed in a cardboard package (bundle).

    Storage conditions:

    In the dark place at a temperature of no higher than 25 ° C.

    Keep out of the reach of children.

    Shelf life:

    3 years.

    Do not use after the expiration date.

    Terms of leave from pharmacies:Without recipe
    Registration number:LP-002286
    Date of registration:28.10.2013 / 26.08.2014
    Expiration Date:28.10.2018
    The owner of the registration certificate:Pharmaplant Fabrication Chemistry Product GmbH Pharmaplant Fabrication Chemistry Product GmbH Germany
    Manufacturer: & nbsp
    Representation: & nbspOZONE LLC OZONE LLC Russia
    Information update date: & nbsp01.05.2017
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