Goodluck - instructions for use, doses, side effects, contraindications

Has a hyperosmotic, laxative effect, stimulates intestinal peristalsis, improves the absorption of phosphates and Ca salts²⁺, promotes the excretion of ammonium ions.

Under the influence of the drug, reproduction occurs Lactobacillus acidophilus, Lactobacillus bifidus In the intestines, under the influence of which lactulose is split into lactic acid (mainly) and partly formic and acetic acids. This increases the osmotic pressure and decreases the pH in the lumen of the large intestine, which leads to ammonia migration from the blood to the intestine, its ionization and retention, as well as an increase in the volume of fecal matter and increased intestinal motility. Excretion of bound ammonium ions occurs with the development of a laxative effect.

Inhibits the formation and absorption of nitrogen-containing toxins in the proximal part of the colon.

Reduces the reproduction of salmonella.

The action occurs 24-48 hours after administration, which is due to the duration of passage of the drug through the gastrointestinal tract.

Pharmacokinetics:

After oral administration lactulose absorbed to a small extent. It reaches the distal parts of the intestine unchanged, where it undergoes intensive biotransformation under the influence of the bacterial flora. When you take 40 - 75 ml, the amount is completely metabolized.Excretion by the kidneys - 3%. Higher doses can be withdrawn completely unchanged.

Indications:

- Constipation, including chronic, during pregnancy, hemorrhoids;

- after surgical interventions on the large intestine and / or in the anal area, for preparation for surgical interventions on the large intestine;

- for softening of the stool (relief of defecation) with pain syndrome after removal of hemorrhoids;

- hepatic encephalopathy, hepatic precoma and coma.

Contraindications:

- Hypersensitivity to the active ingredient or to auxiliary components;

- rectal bleeding;

- colo-, ileostomy;

- suspicion of appendicitis;

- galactosemia;

- patients with lactose intolerance, lactase deficiency, glucose-gapaktos malabsorption;

- an obstruction of an intestine.

Carefully:Diabetes.

Pregnancy and lactation:

Goodluck can be used during pregnancy and lactation at recommended doses and the duration of treatment.

Dosing and Administration:

The daily dose is taken once in the morning during a meal.

Daily doses are determined according to individual need and response.Due to the specific mechanism of action of the drug, the clinical effect occurs in 1-2 days.

If there is no effect after the first two days of taking the drug, the dose can be increased.

RecommendeddayIntramural doses:

Constipation and clinical necessity relief of defecation

	Initial dose (first 3 days)	Maintenance dose
Adults	10-45 ml	10-25 ml
Children 7-14 years old	15 ml	10-15 ml
Children 1-6 years old	5-10 ml	5-10 ml
Children <1 year	5 ml	5 ml

Hepatic precoma, coma and encephalopathy

The initial daily dose is 3 times 30-50 ml each. The daily dose can be 90-190 ml. The supporting daily dose is selected individually so that the "soft stool" is 2-3 times a day. From the calculation, that the pH of the stool was within 5.0-5.5.

Side effects:

In the first days of admission, the appearance of flatulence is possible. Usually this symptom gradually decreases and passes. When taking doses that exceed recommended, there may be abdominal pain and diarrhea, which requires dose adjustment.

When using high doses of the drug for a long time for the prevention and treatment of hepatic precoma and coma, diarrhea and disturbance of water-electrolyte metabolism can develop.

In rare cases, there may be seizures, nausea, headache, dizziness, arrhythmia, myalgia, increased fatigue, weakness. There may be allergic reactions.

Overdose:

There is no evidence of an overdose of the drug. Taking high doses can cause pain in the abdomen, diarrhea and loss of electrolytes. In these cases, the drug should be discontinued.

Interaction:

Antibiotics (neomycin) and antacids reduce the effect of lactulose.

It is not recommended to take lactulose within 2 hours after taking other medications.

Lactulose should not be taken concomitantly with medications, the absorption or excretion of which from the body depends on the pH value in the intestine. Taking the drug leads to a decrease in the pH of the intestinal environment, which changes pH-dependent release of enteric-soluble drugs.

Special instructions:

If there is no clinical effect for several days or if constipation is relapsed after discontinuation of treatment, you should consult with doctor.

Recommended daily doses for the treatment of constipation and ease of defecation can be prescribed to patients with diabetes mellitus.The higher doses used to treat hepatic precoma and coma should be used with increased caution in the presence of diabetes mellitus.

The drug contains galactose, in connection with which its administration is not recommended for patients with lactose intolerance, lactase deficiency, glucose-galactose malabsorption.

At long reception (more than 6 months) control of parameters of ions of a potassium, chlorine and carbonic gas in plasma is necessary.

In gastrocardial syndrome, you should gradually increase the dose to avoid flatulence (which disappears on its own on the 2-3 day of treatment).

In elderly and debilitated patients who take lactulose for more than 6 months, it is recommended to periodically measure the concentration of electrolytes in the blood serum.

When diarrhea occurs, treatment is canceled.

Effect on the ability to drive transp. cf. and fur:

Goodluck has no influence on driving and working with machinery.

Form release / dosage:

Syrup 667 mg / ml.

Packaging:

200 ml of syrup in a bottle of dark glass. Each bottle is supplied with a measuring cup along with instructions for use in a cardboard bundle.

For 15 ml of syrup in a bag of multilayer foil.10 bags together with instructions for use are placed in a cardboard box.

Storage conditions:

At a temperature of no higher than 25 ° C.

Do not freeze!

Keep out of the reach of children!

Shelf life:

2 years.

Shelf life after the opening of the package - 28 days.

Do not use after the expiration date printed on the package.

Terms of leave from pharmacies:Without recipe

Registration number:LSR-003485/10

Date of registration:27.04.2010 / 18.10.2012

Expiration Date:Unlimited

The owner of the registration certificate:AKTAVIS, LTD. AKTAVIS, LTD. Russia

Manufacturer: & nbsp

BALKANPHARMA-TROYAN, AD Bulgaria

Representation: & nbspAktavis, Open Company Aktavis, Open Company

Information update date: & nbsp12.05.2017

Illustrated instructions

Instructions

Good luck (Goodlak)