Inferon - instructions for use, dose, side effects, contraindications

The drug is a mixture of alpha-interferons, leukocyte-synthesized clinically healthy donors in response to the effect of the interferon-virus. The drug does not contain preservatives and antibiotics. The surface antigen of the hepatitis B virus and antibodies to HIV 1, HIV 2, and hepatitis C virus are absent.

Description:Porous hygroscopic mass in the form of a tablet or powder from white to white with a brownish hue of color.

Pharmacotherapeutic group:Cytokine

ATX: & nbsp

L.03.A.B.01 Interferon alfa

Pharmacodynamics:Inferon has an antiviral and immunomodulatory effect. The drug stimulates the phagocytic activity of polymorphonuclear neutrophils and monocytes / macrophages, increases the level of leukocytes (in leukopenia), T-lymphocytes (especially T-helpers) and their functional activity, prevents the development of cytopenia and immunosuppression caused by cytostatic chemotherapy and radiotherapy. With intramuscular injection, the immunobiological effects persist for up to 3 days.

Indications:

- Treatment of viral infections in adults and children in combination with etiotropic and symptomatic means;

- correction of immunodeficiency states in acute and chronic infections of various etiologies;

- in the course of courses of radio and chemotherapy in cancer patients.

Contraindications:

- Hypersensitivity to drugs of protein origin;

- autoimmune diseases (including in the anamnesis);

- acute myocardial infarction;

- diabetes mellitus with ketoacidosis;

- kidney failure;

- epilepsy and / or dysfunction of the central nervous system;

- pregnancy and the period of breastfeeding.

Carefully:Arrhythmias, postinfarction cardiosclerosis, oppression of bone marrow hematopoiesis.

Dosing and Administration:

Intramuscularly. The drug is dissolved in 2 ml of sodium chloride of the solvent to prepare dosage forms for injection of 0.9%. The dissolution time is not more than 1.5 minutes. Dissolved drug is a colorless or brownish tinge transparent liquid, without impurities and sediment. For children under 1 year, 0.5 doses (5000 IU) are used, for children from 1 to 18 years and adults, 1 dose (10,000 IU) is used.

Duration of application of the drug in the treatment of children under 1 year should not exceed 1 month.

Treatment of severe and moderately severe forms of influenza and other acute respiratory viral infections. The first 3-5 days of the drug injected 1 injection daily, and then switch to the administration every other day, a common course of 6-8 injections. If necessary, the course can be extended to a steady improvement in clinical status.

Treatment of acute viral hepatitis. The first 3-7 days of the drug injected 1 injection daily, and then switch to the introduction after 1-2 days, the general course of 14 injections.If necessary, the course can be extended to a stable normalization of clinical symptoms and biochemical indicators.

The use of radiotherapy and chemotherapy in oncology patients. Indication for the use of the drug is leuko- and lymphopenia, other changes in the blood formula, inhibition of phagocytic activity, as well as subjective deterioration of well-being. Infiron injected 1 injection 2-3 times a week during the entire course of cytostatic treatment and for another two weeks after its termination.

Side effects:

Perhaps the development of influenza-like syndrome: myalgia, fever, chills, headache, malaise (symptoms are most pronounced in the first week and gradually weaken).

If you notice any side effects not listed in the instructions, tell your doctor.

Interaction:Combinations with drugs that depress the central nervous system, immunosuppressants, ethanol should be avoided.

Special instructions:

During treatment, it is necessary to control the content of blood elements and the function of the liver.

To eliminate influenza-like symptoms, simultaneous administration of paracetamol is recommended.

Effect on the ability to drive transp. cf. and fur:During the treatment period, care must be taken when driving vehicles and engaging in other potentially dangerous activities that require an increased concentration of attention and speed of psychomotor reactions.

Form release / dosage:

Lyophilizate for solution for intramuscular injection, 10 000 ME. Solvent (sodium chloride solvent for the preparation of dosage forms for injection 0.9%).

Packaging:

Lyophilizate for the preparation of a solution for intramuscular injection: at least 10 000 IU of interferon alfa (1 dose) in an ampoule. Solvent (sodium chloride solvent for the preparation of dosage forms for injection 0.9%) - 2.0 ml per ampoule.

5 ampoules of Inferon complete with 5 ampoules of solvent in a box of cardboard along with instructions for use and a knife or scarifier ampoule (if necessary).

10 ampoules of the preparation without a solvent in a box of cardboard together with instructions for use and a knife or scarifier ampoule (if necessary).

Storage conditions:

Transportation conditions

Transport at a temperature of 2 to 8 ° C.

Storage conditions

Store at temperatures between 2 and 8 ° C out of the reach of children.

Shelf life:

2 years.

Do not use after the expiration date printed on the package.

Terms of leave from pharmacies:On prescription

Registration number:P N003886 / 01

Date of registration:16.03.2010 / 05.11.2015

Expiration Date:Unlimited

The owner of the registration certificate:MICROGEN FGUP Scientific and Production Association MICROGEN FGUP Scientific and Production Association Russia

Manufacturer: & nbsp

MICROGEN FGUP NGO Russia

Information update date: & nbsp26.10.2017

Illustrated instructions

Instructions

Inferon (Inferon)