Influnet - instructions for use, dose, side effects, contraindications

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Dosage form: & nbspcapsules

Composition:

Composition per one capsule

Active substances: paracetamol - 175 mg, ascorbic acid - 150 mg, succinic acid - 60 mg, rutoside trihydrate (in terms of rutozide) - 10 mg, phenylephrine hydrochloride - 2.5 mg.

Excipients: giprolose - 4,5 mg, silicon dioxide colloid - 2,5 mg, lactose monohydrate - 21,3 mg, magnesium stearate - 4,2 mg.

Capsule hard gelatin contains: gelatin, indigocarmine (E 132), blue diamond dye (E 133), titanium dioxide (E 171).

Description:

Capsules number 0, the case is blue, the lid is blue.

The contents of the capsules are a mixture of powder and / or granules of yellow with a greenish tint of color. It is allowed to have lumps, which when pressed with a glass rod are easily turned into a powder.

Pharmacotherapeutic group:ORZ and "colds" of symptoms remedy

ATX: & nbsp

Other combined drugs used for catarrhal diseases

Pharmacodynamics:

Combined drug, has antipyretic, analgesic, angioprotective, anticongestive (anti-edematous) effect.

Paracetamol has antipyretic, analgesic effect.

Ascorbic acid (vitamin C) is involved in the regulation of carbohydrate metabolism, redox processes, the synthesis of steroid hormones, tissue regeneration, activates immune responses, reduces the permeability of capillaries, enhances detoxification of the liver, regulates blood clotting processes.It replenishes vitamin C deficiency with "cold" diseases.

succinic acid strengthens biochemical and physiological recovery processes. Has hepatoprotective, immunomodulating and antioxidant effect. Activates energy processes in the mitochondria, normalizes the permeability of cell membranes, is an intermediate of the Krebs cycle. In combination with drugs enhances their positive effect and reduces the manifestation of toxic effects.

Rutozid reduces permeability of capillaries, removes puffiness and inflammation, strengthens the vascular wall, inhibits aggregation and increases the degree of erythrocyte deformation.

Phenylephrine stimulates postsynaptic alpha-adrenergic receptors, reduces edema and hyperemia of the nasal mucosa, restores free breathing, reduces pressure in the paranasal sinuses and the middle ear.

Indications:Symptomatic treatment of "colds" and flu, accompanied by fever, headache, chills, nasal congestion, pain in the throat and nasal sinuses.

Contraindications:

If you have any of the following diseases or conditions, always consult a doctor before taking the drug.

Increased individual sensitivity to one or more of the components included in the formulation; severe liver and kidney damage (acute hepatitis, acute pyelonephritis, acute glomerulonephritis, or exacerbation of chronic diseases of these organs); peptic ulcer of the stomach and duodenum; glaucoma; propensity to thrombosis; diabetes; arterial hypertension, bradycardia, ventricular tachycardia, heart failure, conduction disorders, ventricular fibrillation, severe atherosclerosis, severe aortic stenosis, acute myocardial infarction; pheochromocytoma, hyperthyroidism, prostatic hyperplasia; simultaneous reception of tricyclic antidepressants, beta adrenoblockers, MAO inhibitors (and within 14 days after their cancellation), other medications containing paracetamol. Lactose intolerance, lactase deficiency, glucose-galactose malabsorption syndrome (due to the presence of lactose in the composition). Pregnancy, the period of breastfeeding.Children under 18 years.

Carefully:

If you have any of the following diseases or conditions, always consult a doctor before taking the drug.

Benign hyperbilirubinemia, congenital deficiency of glucose-6-phosphate dehydrogenase.

Dosing and Administration:

Inside, after eating, with plenty of water. Take 2 capsules after 4-6 hours, but no more than 4 times a day, for 3 days. The maximum daily dose is 8 capsules.

If within 3 days after receiving the drug did not come feel better, you should stop taking the drug and consult a doctor.

Side effects:

When used in recommended doses and duration, the drug is well tolerated, side effects develop extremely rarely.

From the cardiovascular and circulatory systems: agranulocytosis (absence or marked decrease of granulocytes in peripheral blood), thrombocytopenia (low platelet counts), thrombocytosis (increasing the number of platelets) giperprotrombinemiya (increase of prothrombin in the blood plasma) erythropenia (decreased red blood cell count), leukocytosis (increase in the number of leukocytes), anemia (reduction of hemoglobin); increased blood pressure, bradycardia, arrhythmia, angina.

From the nervous system and sensory organs: headache, agitation, irritability, restlessness, weakness, dizziness, respiratory depression, tremor (trembling).

On the part of the digestive system: nausea, vomiting, diarrhea (diarrhea).

From the side of metabolism: metabolic disorders, suppression of glycogen synthesis, excessive formation of corticosteroids, sodium and water retention, hypokalemia (decrease in potassium content in blood plasma).

From the genitourinary system: increased or decreased diuresis, damage to the glomerular apparatus of the kidneys, the formation of oxalate urinary stones.

Allergic reactions: skin rash, hyperemia (redness) of the skin.

If any of the side effects listed in the manual are aggravated, or if you notice any other side effects not listed in the instructions, tell your doctor.

Overdose:

Symptoms (an overdose is mainly caused by paracetamol): pallor of the skin, anorexia (lack of appetite), nausea, vomiting and abdominal pain, increased activity of "liver" transaminases, increased prothrombin time, hepatonecrosis, arrhythmia, ventricular tachycardia, increased blood pressure.

Treatment: on a pre-hospital stage - washing of a stomach, reception of the activated coal. Symptomatic therapy. Antidote paracetamol - acetylcysteine.

In case of overdose, see a doctor.

Interaction:

If you need to share with other medications, you should consult your doctor.

Stimulants of microsomal oxidation in the liver (phenytoin, ethanol, barbiturates, rifampicin, phenylbutazone, tricyclic antidepressants) increase the production of hydroxylated active metabolites of paracetamol, which allows the development of severe intoxication with small overdoses.

Paracetamol increases the effects of MAO inhibitors, sedatives, ethanol.

Antidepressants, antiparkinsonian, antipsychotic drugs, phenothiazine derivatives increase the risk of urinary retention, dry mouth, constipation. Glucocorticosteroids increase the risk of developing glaucoma.

Phenylephrine reduces the hypotensive effect of guanethidine.

Guanethidine increases alpha-adrenostimulating effect, and tricyclic antidepressants - sympathomimetic effects of phenylephrine.

Special instructions:

The duration of the drug without consulting a doctor should not exceed 3 days.

Distorts the results of laboratory tests evaluating the concentration of glucose and uric acid in the plasma.

Persons prone to ethanol use should consult a doctor before starting treatment with the drug, since paracetamol can have a damaging effect on the liver.

Form release / dosage:Capsules.

Packaging:

10 capsules in a contour cell box made of polyvinylchloride film and aluminum foil.

1, 2 or 4 contour mesh packages together with instructions for use in a pack of cardboard.

Storage conditions:

In a dry, protected from light place at a temperature of no higher than 25 ° C.

Keep out of the reach of children.

Shelf life:

2 years.

Do not use after the expiration date printed on the package.

Terms of leave from pharmacies:Without recipe

Registration number:LSR-003416/10

Date of registration:23.04.2010 / 08.07.2016

Expiration Date:Unlimited

The owner of the registration certificate:Anvilab, OOO Anvilab, OOO Russia

Manufacturer: & nbsp

FARMPROJECT, CJSC Russia

Information update date: & nbsp26.10.2017

Illustrated instructions

Instructions

Influnet® (Influnet®)