Instenon - instructions for use, dose, side effects, contraindications

Active substanceHeckbenzene + Etamivan + EthophillinHeckbenzene + Etamivan + Ethophillin

Similar drugsTo uncover

Instenon®

solution in / in w / m

Nycomed Austria GmbH Austria

Instenon®

pills inwards

Nycomed Austria GmbH Austria

Dosage form: & nbspcoated tablets

Composition:

One tablet contains:

Instenon tablets coated with 20 mg + 50 mg + 60 mg

active substances: hexiodine dihydrochloride 20 mg, etamivan 50 mg, etofillin 60 mg;

Excipients: magnesium stearate 2.00 mg, talc 4.00 mg, lactose monohydrate 10.00 mg, pregelatinized starch 7.67 mg, corn starch 36.33 mg.

Shell composition: wax mountain glycol 0.10 mg, povidone K-30 1.20 mg, macrogol 6000 2.40 mg, acacia gum 4.75 mg, talc 26.75 mg, sucrose 34.33 mg, titanium dioxide 0.47 mg.

Instenon tablets coated with 60 mg + 100 mg + 60 mg

Active substance: hexiodine dihydrochloride 60 mg, etamivan 100 mg, etofillin 60 mg.

Excipients: magnesium stearate 3.00 mg, talc 8.00 mg, lactose monohydrate 12.00 mg, pregelatinized starch 17.12 mg, corn starch 29.88 mg.

Shell composition: wax mountain glycol 0.10 mg, povidone K-30 1.4 mg, macrogol 6000 2.80 mg, acacia gum 5.60 mg, talc 28.00 mg, sucrose 39.30 mg, titanium dioxide 1.4 mg, dye sunset yellow 1.40 mg.

Description:

Instenon tablets coated with 20 mg + 50 mg + 60 mg

Round tablets with a flat, shiny surface, covered with a white shell. Type of tablet on the break: oologo color.

Instenon tablets coated with 60 mg + 100 mg + 60 mg

Round, biconvex tablets with a shiny surface, covered with an orange coating. Type of tablet on the break: inside the white color, along the edges a thin layer of orange.

Pharmacotherapeutic group:Vasodilator

ATX: & nbsp

C.01.E.X Other combination drugs for the treatment of heart disease

Pharmacodynamics:

Instenon ® is a combined preparation that improves cerebral circulation and metabolism. Ethamane due to activation of the reticular formation normalizes the functional state of neural complexes of the cortex and subcortical structures.

Hecksbordin improves the utilization of glucose and oxygen by activating anaerobic glycolysis and pentose cycles (realized only under conditions of ischemia and hypoxia, when the cycle of aerobic oxidative phosphorylation is disrupted).

Ethophylline activates myocardial metabolism, increases the minute volume of the heart, which increases the perfusion pressure in the vessels of the marginal zone of ischemia. This does not change the systemic blood pressure.Exciting effect on the nervous system is also manifested in the stimulation of subcortical formations, the midbrain, stem centers and nuclei (respiratory, sucking to motor, centers of vegetative regulation, as well as nuclei of cranial nerves, primarily - wandering nerves).

Pharmacokinetics:Special studies to study the pharmacokinetics of the drug Instenon was not conducted, due to the lack of necessary pharmacokinetic methods.

Indications:Chronic insufficiency of cerebral circulation, post-stroke states, vertigo of central genesis.

Contraindications:Pronounced agitation, convulsions, epilepsy, increased intracranial pressure, cerebral hemorrhage, hypersensitivity, pregnancy, lactation, children under 18 years.

Carefully:Recently suffered stroke and stenosis of the carotid artery.

Dosing and Administration:Depending on the severity of the condition, take 1-2 tablets 3 times a day (for a dosage of 20 mg + 50 mg + 60 mg) or 1 tablet 3 times a day (for a dosage of 60 mg + 100 mg + 60 mg) without chewing , during or after a meal, with a small amount of liquid.If necessary, you can increase the daily intake to 5 tablets (for a dosage of 60 mg + 100 mg + 60 mg) per day, divided into several doses. The duration of treatment should be at least 6 weeks.

Side effects:Headache, hyperemia of the face, lowering of arterial pressure, tachycardia (transient).

Overdose:

Symptoms: tachycardia, increased severity of side effects.

Treatment: gastric lavage, Activated carbon, symptomatic therapy.

Interaction:

Strengthens the effect of antiplatelet agents (acetylsalicylic acid and etc.).

Very high doses of caffeine can impair the action of Instenon® (large amounts of coffee and tea should be avoided).

Special instructions:

Effect on the ability to drive transp. cf. and fur:During the treatment period, care must be taken when dealing with potentially dangerous activities requiring increased concentration of attention and speed of psychomotor reactions.

Form release / dosage:The coated tablets are 20 mg + 50 mg + 60 mg and 60 mg + 100 mg + 60 mg.

Packaging:

For 10 tablets in a blister of lacquered aluminum foil and a polymer film of PVC / PVDC.

Tablets 20 mg + 50 mg + 60 mg: 3 blisters together with instructions for use are placed in a cardboard box.

Tablets 60 mg + 100 mg + 60 mg: 5 blisters together with instructions for use are placed in a cardboard box.

Storage conditions:List B. In the dark place at a temperature of no higher than 25 ° C. Keep out of the reach of children.

Shelf life:5 years. Do not use after the expiration date.

Terms of leave from pharmacies:On prescription

Registration number:П N014738 / 02

Date of registration:13.10.2008 / 20.02.2012

Expiration Date:Unlimited

The owner of the registration certificate:Nycomed Austria GmbHNycomed Austria GmbH Austria

Manufacturer: & nbsp

GLOBOPHARM Pharmazeutische Produktions- und Handelsgesellschaft, mbH Austria

Representation: & nbspNycomed Distribution Ltd.Nycomed Distribution Ltd.

Information update date: & nbsp30.10.2017

Illustrated instructions

Instructions

Instenon® (Instenon®)