Calcium D3 Classic - instructions for use, dose, side effects, contraindications

Calcium carbonate 1250 mg, calculated on calcium 500 mg; Cholecalciferol granulate 100000 IU / g 2.2 mg, at recalculation on colcalciferol 5 μg (200 ME) (colcalciferol, D, L-alpha-tocopherol, triglycerides medium-chain, sucrose, acacias kacopper, starch corn, calcium phosphate, water)

Calcium carbonate 1250 mg, calculated on calcium 500 mg; Cholecalciferol granulate 100000 IU / g 4.4 mg, at recalculation on colcalciferol 10 μg (400 ME) (colcalciferol, D,L-alpha-tocopherol, triglycerides medium-chain, sucrose, acacias gum, starch corn, calcium phosphate, water).

Auxiliary components:

mannitol, lactitol, dextrates, sodium saccharinate (saccharin sodium), magnesium stearate, flavoring "apple" or "orange."

Description:

Tablets are white or almost white, round, flat-cylindrical with a bevel, without risks, with a characteristic weak apple (at a dosage of 500 mg + 200 ME) or orange (at a dosage of 500 mg + 400 ME) smell.

Pharmacotherapeutic group:Calcium-phosphorus exchange regulator

ATX: & nbsp

A.12.A.X Calcium preparations in combination with other drugs

Pharmacodynamics:

Combined drug regulating the exchange of calcium and phosphorus in the body (bones, teeth, nails, hair, muscles). Reduces resorption (resorption) and increases bone density, making up for lack of calcium and vitamin D₃ in the body, it is necessary for the mineralization of teeth. Calcium is involved in the regulation of nerve conduction, muscle contractions and is a component of the blood coagulation system.

Vitamin D₃ increases the absorption of calcium in the intestine.

The use of calcium and vitamin D₃ prevents the increase in the production of parathyroid hormone (PTH), which is a stimulator of increased bone resorption (leaching calcium from the bones).

Pharmacokinetics:

Vitamin D₃ absorbed in the small intestine. Calcium is absorbed in ionized form in the proximal small intestine by means of an active, D₃vitamin of the dependent transport mechanism.

Indications:

To fill the deficiency of calcium and vitamin D₃ in organism:

- with osteoporosis and its complications (fracture of bones);

- during pregnancy and lactation;

- in the period of intensive growth and development of children and adolescents;

- with diet and unbalanced diet.

Contraindications:

- Hypercalcemia (elevated calcium concentration in the blood);

- Hypercalciuria (increased calcium in the urine);

- Nephrolithiasis;

- Hypervitaminosis of Vitamin D₃;

- Hypersensitivity to the components of the drug;

- Severe renal insufficiency;

- Active form of tuberculosis;

- Sarcoidosis;

- Children under 3 years of age (for a dose of 500 mg + 200 ME);

- Children under 12 years of age (for a dose of 500 mg + 400 ME).

Carefully:

Renal failure, benign granulomatosis, pregnancy, lactation, cardiac glycosides and thiazide diuretics, children's age (up to 12 years).

Pregnancy and lactation:

The daily dose should not exceed 1500 mg of calcium and 600 ME vitamin A D₃. Hypercalcemia, which develops against the background of an overdose during pregnancy, can cause defects in the child's mental and physical development.

Vitamin D₃ and its metabolites can penetrate into breast milk, so you need to consider the intake of calcium and vitamin D₃ from other sources in the mother and child.

Dosing and Administration:

For a dose of 500 mg + 200 ME

Adults:

in the complex therapy of osteoporosis - 1 tablet 2-3 times a day; for the prevention of osteoporosis - 1 tablet 2 times a day.

To fill the deficiency of calcium and vitamin D₃

Adults and children over 12 years of age - 1 tablet 2 times a day in the morning and in the evening.

Children from 5 years to 12 years - 1-2 tablets per day.

Children from 3 to 5 years - dosage according to the doctor's recommendation. The tablet can be chewed or resorbed and taken with food.

For a dose of 500 mg + 400 ME

Adults:

for the course of prevention of osteoporosis - 2 tablets per day, one morning and one evening, mainly during meals; in the complex therapy of osteoporosis - 1 tablet 2-3 times a day.

To fill the deficiency of calcium and vitamin D₃

Adults and children over 12 years of age - 1 tablet a day.

The tablet can be chewed or resorbed and taken with food.Before starting reception, consult a doctor.

Side effects:

Allergic reactions, dysfunction of the gastrointestinal tract (constipation or diarrhea, flatulence, nausea, abdominal pain), hypercalcemia and hypercalciuria (elevated calcium in the blood or urine).

Overdose:

Overdose Symptoms: anorexia, thirst, polyuria, decrease appetite, dizziness, fainting, weakness, nausea, vomiting, hypercalciuria, hypercalcemia, hypercreatinemia. With prolonged use of excessive doses of calcification of blood vessels and tissues. Laboratory indicators for overdose: hypercalcemia (Ca2 + in plasma about 2.6 mmol), hypercalciuria.

In case of clinical symptoms of overdose, the concentration of calcium and creatinine in the blood should be determined. In the case of an elevated concentration of calcium or creatinine in the blood serum should reduce the dose of the drug or temporarily stop treatment.

In the case of hypercalciuria exceeding 7.5 mmol / day (300 mg / day), it is necessary to reduce the dose or stop taking.

Treatment: rehydration, the use of loop diuretics (eg, furosemide), glucocorticosteroids, calcitonin, bisphosphonates,in severe cases, hemodialysis.

In case of signs of overdose, seek medical advice.

Interaction:

- Vitamin activity D₃ can decrease with its simultaneous use with phenytoin or barbiturates.

- With simultaneous treatment with cardiac glycosides, ECG and clinical monitoring are necessary, calcium preparations can potentiate the therapeutic and toxic effects of cardiac glycosides.

- Preparations of calcium and vitamin D₃ can increase the absorption of tetracyclines from the gastrointestinal tract. Therefore, the time interval between taking a tetracycline drug and Calcium D₃ CLASSIC must be at least 3 hours.

- To prevent the absorption of bisphosphonate or sodium fluoride drugs, it is recommended to take Calcium D₃ CLASSIC not earlier than 2 hours after their admission.

- Glucocorticosteroids reduce the absorption of calcium, so treatment with glucocorticosteroids may require an increase in the dose of Calcium D₃ CLASSIC.

- Simultaneous treatment with colestyramine or laxatives based on mineral or vegetable oil can reduce the absorption of vitamin A D₃.

- With the simultaneous use of thiazide diuretics, the risk of hypercalcemia increases, because they increase the tubular reabsorption of calcium.

Furosemide and other "loop diuretics", on the contrary, increase the excretion of calcium by the kidneys.

- In patients who simultaneously take cardiac glycosides and / or diuretics, it is necessary to monitor the concentration of calcium and creatinine in the serum.

Special instructions:

- To avoid an overdose, it is necessary to take into account the additional intake of the vitamin D₃ from other sources.

- The intake of food containing oxalates (sorrel, spinach) and phytidine (cereals) reduces the absorption of calcium, so it should not be take Calcium D₃ CLASSIC for two hours after taking sorrel, spinach, cereals.

Effect on the ability to drive transp. cf. and fur:Not described.

Form release / dosage:

Tablets chewing (apple) 500 mg + 200 ME and (orange) 500 mg + 400 ME.

Packaging:

10, 15, 20, 30 tablets are placed in a plastic case for medicines or 2, 4, 6, 8, 10 tablets are placed in a contoured cell pack of a polyvinylchloride film and foil of aluminum printed lacquered, or 2, 4, 6, 8,10 tablets are placed in a contour non-jawed package made from a combination film material or from a combined multi-layered material or a foil laminated packaging.

For 1, 2 plastic pencil cases or 1, 2, 3, 4, 5 contour packs with instructions for use in a pack of cardboard.

Storage conditions:

In a dry, protected from light place at a temperature of no higher than 25 ° C. Keep out of the reach of children.

Shelf life:

2 years.

Do not use after the expiry date printed on the package.

Terms of leave from pharmacies:Without recipe

Registration number:LSR-005425/10

Date of registration:10.06.2010

Expiration Date:Unlimited

The owner of the registration certificate:OBOLENSKOE PHARMACEUTICAL ENTERPRISE, CJSC OBOLENSKOE PHARMACEUTICAL ENTERPRISE, CJSC Russia

Manufacturer: & nbsp

OBOLENSKOE PHARMACEUTICAL ENTERPRISE, CJSC Russia

Information update date: & nbsp25.11.2017

Illustrated instructions

Instructions

Calcium D3 Classic (Calcium D3 Classic)