Calcium + Vitamin C - instructions for use, dose, side effects, contraindications

Active substanceAscorbic acid + Calcium carbonateAscorbic acid + Calcium carbonate

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Calcium + Vitamin C

pills inwards

VALEANT, LLC Russia

Dosage form: & nbsptablets, effervescent

Composition:

For one tablet:

Active substances:

Calcium carbonate 500.0 mg

Ascorbic acid 180.0 mg

Excipients: sodium bicarbonate 520.0 mg, citric acid 840.0 mg, sorbitol 832.5 mg, sodium saccharinate dihydrate 15.0 mg, macrogol 60.0 mg, orange flavoring 50.0 mg, dye sunset yellow (E-110) 2.5 mg.

Description:

Tablets are flat-cylindrical round with a beveled edge from pale pink to pinkish color with lighter and darker patches, with a dividing risk on one side and with the smell of orange.

Pharmacotherapeutic group:Calcium-phosphorus exchange regulator

ATX: & nbsp

A.11.G.B.01 Ascorbic acid and calcium

Pharmacodynamics:

Combined drug, the effect of which is due to its constituent components. Regulates the phosphorus-calcium metabolism, increases the density of bone tissue, replenishes the lack of calcium and ascorbic acid in the body, increases absorption of calcium in the intestine and reabsorption of phosphates in the kidneys, promotes the mineralization of bones.

Calcium carbonate - is involved in the formation of bone tissue, blood clotting, in the maintenance of stable cardiac activity,in the implementation of the processes of transmission of nerve impulses.

Ascorbic acid (vitamin C) plays an important role in regulating oxidation-reduction processes, tissue regeneration, blood clotting, normalizes permeability of capillaries, and has a pronounced antioxidant activity.

Pharmacokinetics:

After dissolving the tablet, calcium citrate is formed. This form provides absorption of 30-40% of the intake of calcium. It is excreted with saliva, then, with bile, pancreatic and intestinal secrets, kidneys (depends on glomerular filtration and reabsorption of calcium).

Calcium is absorbed in ionized form in the proximal part of the small intestine by means of an active Dvitamin of the dependent transport mechanism. Ascorbic acid completely absorbed from the gastrointestinal tract (GIT).

Indications:

Treatment and prevention of calcium and vitamin C deficiency in the period of intensive growth of adolescents, during pregnancy, during lactation, with increased mental and physical exertion.

Contraindications:

Hypersensitivity to the components of the drug, an increased concentration of calcium in the blood and urine (hypercalcemia, hypercalciuria),chronic renal failure, nephrourolythiasis, nephrocalcinosis, peptic ulcer and duodenal ulcer, erosive gastroduodenitis; atherosclerosis, thrombosis, children under 12 years old.

Carefully:Admission of glycosides and thiazide diuretics.

Pregnancy and lactation:

Calcium enters the breast milk. During pregnancy, the daily dose of calcium should not exceed 1500 mg. Hypercalcemia during pregnancy can cause defects in the fetus's physical and mental development.

Dosing and Administration:

Inside.

Adults and children from 12 years: 1-2 tablets per day, previously dissolving the pill in a glass of water. The course of taking the drug is no more than 30 days. Depending on the clinical picture, the duration of admission and the second course should be agreed with the doctor.

Side effects:

There may be mild violations of the gastrointestinal tract (flatulence, constipation, diarrhea); allergic reactions, dyspnea, fever; when taken in high doses - headache, fatigue, thirst, polyuria.

Overdose:

No cases of acute overdose have been reported. There may be abnormalities on the part of the gastrointestinal tract (abdominal pain, nausea, vomiting).

Treatment: the introduction of a large amount of fluid in the body, the use of loop diuretics (eg, furosemide), glucocorticosteroids, calcitonin, bisphosphonates.

In case of signs of overdose, seek medical advice. In case of clinical symptoms of overdose, the concentration of calcium and creatinine in the blood should be determined. In the case of an elevated concentration of calcium or creatinine in the blood serum should reduce the dose of the drug or temporarily stop treatment.

In the case of hypercalciuria, exceeding 7.5 mmol / day (300 mg / day), it is necessary to reduce the dose or stop taking.

Interaction:

The drug can reduce the absorption of estramustine, etidronate and other bisphosphonates, phenytoin, quinolones, oral tetracycline antibiotics and preparations of fluoride. The interval between taking the tablets "Calcium + Vitamin C" and the above drugs should be at least 3 hours.

Simultaneous administration of vitamin A D and its derivatives increases the absorption of calcium.

Absorption of calcium from the digestive tract can decrease with the simultaneous intake of certain types of food, for example, spinach, rhubarb, bran, and cereals.

When administered in high doses along with vitamin D and its derivatives of calcium can reduce the effect of verapamil and, possibly, other calcium channel blockers. Oral administration of high doses of calcium to patients receiving digitalis preparations may increase the risk of arrhythmias.

Thiazide diuretics reduce the excretion of calcium in the urine. Therefore, one should keep in mind the risk of developing hypercalcemia in their simultaneous use with effervescent tablets "Calcium + Vitamin C".

Special instructions:

In patients with minor hypercalciuria (exceeding 300 mg = 7.5 mmol / day), with little or moderate renal impairment, and with anamnestic indications for urolithiasis, regular monitoring of urinary calcium excretion is required. If necessary, reduce the dose or cancel it. Patients with a tendency to form concrements in the urinary tract are recommended to increase fluid intake.

When treating calcium drugs should avoid taking large doses of vitamin A D or its derivatives, unless there is specific evidence for this.

Effect on the ability to drive transp. cf. and fur:The drug does not affect the ability to drive vehicles and work with precise mechanisms.

Form release / dosage:

The tablets are effervescent.

Packaging:For 10, 12 tablets in a plastic case. 1 pencil case in a cardboard box or in an envelope with an attachment for hanging along with instructions for use.

Storage conditions:

At a temperature of no higher than 25 ° C.

Keep out of the reach of children!

Shelf life:3 years.

Terms of leave from pharmacies:On prescription

Registration number:П N010436

Date of registration:18.08.2010 / 30.04.2014

Expiration Date:Unlimited

The owner of the registration certificate:VALEANT, LLC VALEANT, LLC Russia

Manufacturer: & nbsp

NATUR PRODUKT PHARMA, Sp. z o.o. Poland

Representation: & nbspVALEANT LLC VALEANT LLC Russia

Information update date: & nbsp25.11.2017

Illustrated instructions

Instructions

Calcium + Vitamin C (Calcium + Vitamin C)