Corvalol (Corvalol)

Composition Pharmacodynamics Indications Carefully Contraindications Dosing and Administration Side effects Form release / dosage
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Dosage form: & nbspdrops for oral administration
Composition:

Active substances:

Ethyl bromoisovaleric anhydride 2.00 g

Phenobarbital - 1.826 g

Mint pepper leaves oil - 0.142 g

Excipients:

Sodium hydroxide 0.315 g

Ethanol (ethyl alcohol) 95% - 58 ml

Waters purified - up to 100 ml

Description:Transparent colorless liquid with a characteristic odor.
Pharmacotherapeutic group:Sedative remedy
ATX: & nbsp
  • Other sleeping pills and sedatives
    • Pharmacodynamics:

    Combined drug, the effect of which is due to the properties of its constituents. Has a sedative and spasmolytic effect. Facilitates the onset of natural sleep.

    Ethyl bromoisovalerian has a sedative (similar to valerian effect) and spasmolytic effect due to stimulation of the predominantly oral and nasopharyngeal receptors, a decrease in reflex excitability in the central parts of the nervous system and an increase in inhibition in neurons of the cortex and subcortical structures of the brain, as well as a decrease in activity of the central vasomotor centers and direct local antispasmodic effect on smooth muscles.

    Phenobarbital enhances the sedative effect of other components, helps to reduce excitation of the central nervous system (CNS) and facilitates the onset of sleep.

    Peppermint oil has a reflex vasodilating, spasmolytic, mild choleretic, antiseptic effect. The mechanism of action is associated with the ability to irritate the "cold" receptors of the oral mucosa and reflexively expand primarily the vessels of the heart and brain. Eliminates the phenomena of flatulence due to irritation of the receptors of the gastrointestinal mucosa, strengthening the peristalsis of the intestine.

    Indications:Corvalol prescribed as a sedative and vasodilator in functional disorders of the cardiovascular system, with neurotic-like states accompanied by increased irritability, disturbance of sleep, tachycardia, a state of excitement with severe autonomic manifestations, as well as an antispasmodic - with cramps.
    Contraindications:Hypersensitivity to the components of the drug; pronounced renal dysfunction and / or liver, lactation (if necessary, the appointment during lactation should decide the issue of termination of breastfeeding), pregnancy.
    Dosing and Administration:

    Dosage is set individually.Inside before eating, previously dissolved in a small amount (30-40) of water, 2-3 times a day. A single dose, if necessary (for example, with tachycardia) can be increased to 40-50 cap.

    Children - 3-15 drops per day (depending on the age and clinical picture of the disease).

    Duration of the drug is determined by the doctor individually.

    Side effects:

    Drowsiness, dizziness, slow heart rate, decreased ability to concentrate, allergic reactions.

    With prolonged use - the phenomenon of bromism, addiction, drug dependence, withdrawal syndrome.

    Overdose:

    Symptoms: depression of the central nervous system, nystagmus, ataxia, decreased blood pressure, violations of the blood formula, excitation, chronic intoxication with bromine (depression, apathy, rhinitis, conjunctivitis, hemorrhagic diathesis, impaired coordination of movements).

    Treatment: symptomatic, with CNS depression - caffeine, nikethamide.

    Interaction:Drugs that depress the central nervous system intensify the effect. Phenobarbital (inducer of microsomal oxidation) can reduce the effectiveness of drugs metabolized in the liver (including coumarin derivatives, griseofulvin, glucocorticosteroids, oral contraceptives); strengthens the action of local anesthetic, analgesic and hypnotics.
    Special instructions:The preparation contains 58% by volume of ethanol and phenobarbital, so patients who are taking Corvalol are not recommended to engage in activities associated with increased attention and requiring rapidity of mental and motor reactions.
    Form release / dosage:Drops for oral administration.
    Packaging:

    For 15, 25, 40, 50 ml in bottles or bottles of orange glass with a screw mouth, sealed with lids unified cork-screwed or stoppers with lids or stoppers with drip caps with lids made of polyethylene or polymeric materials.

    Each bottle or bottle-dropper is placed in a cardboard box.

    Storage conditions:

    In the dark place at a temperature of no higher than 25 ° C.

    Keep out of the reach of children.

    Shelf life:

    2 years.

    Do not use after expiry date.

    Terms of leave from pharmacies:Without recipe
    Registration number:LSR-001750/09
    Date of registration:10.03.2009 / 11.09.2012
    The owner of the registration certificate:GIPPOKRAT, LLC GIPPOKRAT, LLC Russia
    Manufacturer: & nbsp
    Information update date: & nbsp18.01.2018
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