Corvalol (Corvalol)

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"Trade product
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Composition Pharmacodynamics Indications Carefully Contraindications Dosing and Administration Side effects Form release / dosage
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Dosage form: & nbspdrops for oral administration
Composition:

Active substances:

Ethyl bromoisovaleric acid 2.0 g

(ethyl alpha-bromoisovaleric acid ethyl ester)

Phenobarbital 1.826 g

Peppermint oil 0.142 g

Excipients:

Sodium hydroxide 0.315 g

Ethyl alcohol 95% (Ethanol) 58 ml

Purified water 42 ml

Description:Transparent colorless liquid with a specific odor.
Pharmacotherapeutic group:Sedative remedy
ATX: & nbsp
  • Other sleeping pills and sedatives
    • Pharmacodynamics:

    Combined drug, the effect of which is due to the properties of its constituent substances.

    Has a sedative and spasmolytic effect. Facilitates the onset of natural sleep.

    Ethyl ester of α-bromizovaleric acid has sedative (similar to the valerian effect) and spasmolytic effect, which is caused by irritation of the predominantly oral and nasopharyngeal receptors, a decrease in reflex excitability in the central parts of the nervous system, and an increase in inhibition in neurons of the cortex and subcortical structures of the brain, activity of the central vasomotor centers and direct local antispasmodic effect on smooth muscles.

    Phenobarbital enhances the sedative effect of other components, helps to reduce excitation of the central nervous system and facilitates the onset of sleep. Peppermint oil has a reflex vasodilating and spasmolytic, mild choleretic, antiseptic effect. The mechanism of action is associated with the ability to irritate the "cold" receptors of the oral mucosa and reflexively expand primarily the vessels of the heart and brain. Eliminates the phenomena of flatulence due to irritation of the receptors of the mucous membrane of the gastrointestinal tract, strengthening the peristalsis of the intestine.

    Indications:Corvalol is prescribed as a symptomatic (calming and vasodilating) remedy for functional disorders of the cardiovascular system, with neurosis-like conditions, accompanied by increased irritability, dysplasia, tachycardia, a state of excitation with pronounced vegetative manifestations, and as an antispasmodic agent in spasms of the intestine.
    Contraindications:

    Hypersensitivity to the components of the drug; severe impairment of kidney and / or liver function.

    Pregnancy and the period of breastfeeding, children under 3 years old, alcoholism, traumatic brain injury or brain disease (in connection with the content of ethanol).

    Carefully:Child age from 3 years.
    Pregnancy and lactation:It is not recommended to apply the drug / during pregnancy. If you need to use the drug during lactation, you should decide whether to stop breastfeeding for the period of treatment.
    Dosing and Administration:Inside, before eating, pre-dissolved in a small amount (30-50 ml) of water. The dose and duration of application is determined individually. A single dose in adults - 30 drops, if necessary (for example, with severe tachycardia), a single dose can be maximally increased to 40-50 drops. Multiplicity of reception - 2-3 times a day. Children from 3 years for one appointment - 1 drop per year of life of the child per day. The need for a repeated dose is determined by the doctor depending on the clinical picture of the disease.
    Side effects:Drowsiness, dizziness, slow heart rate, decreased ability to concentrate, allergic reactions.With long-term admission - the phenomenon of bromism, addiction, drug dependence, withdrawal syndrome.
    Overdose:

    Symptoms: depression of the central nervous system, nystagmus, ataxia, lowering blood pressure, violation of the blood formula, excitation, chronic intoxication with bromine (depression, apathy, rhinitis, conjunctivitis, hemorrhagic diathesis, impaired coordination of movements).

    Treatment: symptomatic, with oppression of the central nervous system- caffeine, nikethamide.

    Interaction:

    Drugs that depress the central nervous system, enhance the effect. Phenobarbital (inducer of microsomal oxidation) can reduce the effectiveness of drugs metabolized in the liver (including coumarin derivatives, griseofulvin glucocorticosteroids, oral contraceptives; strengthens the action of local anesthetic, analgesic and hypnotic drugs.

    Special instructions:The preparation contains 58% by volume of ethanol and phenobarbital, so patients who are taking Corvalol are not recommended to engage in activities associated with increased attention and requiring rapidity of mental and motor reactions.
    Effect on the ability to drive transp.cf. and fur:The drug contains 58 volume percent ethanol and phenobarbital, therefore patients taking Corvalol are not recommended to engage in activities associated with increased attention and requiring quick mental and motor reactions.
    Form release / dosage:Drops for oral administration.
    Packaging:
    To 25 ml, 50 ml, into the bottles of droppers of orange glass! The bottle-dropper together with the instruction for medical use in a pack of cardboard. The text of instructions for use is applied on the pack.
    Storage conditions:In the dark place at a temperature of 8 ° C to 25 ° C. Keep out of the reach of children.
    Shelf life:

    1 year 6 months.

    Do not use after the date shown on the package.

    Terms of leave from pharmacies:Without recipe
    Registration number:LP-000702
    Date of registration:28.09.2011
    Expiration Date:28.09.2016
    Date of cancellation:2017-07-25
    The owner of the registration certificate:TROITSKY IODNY FACTORY, OJSC TROITSKY IODNY FACTORY, OJSC Russia
    Manufacturer: & nbsp
    Information update date: & nbsp18.01.2018
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