Corvalol - instructions for use, dose, side effects, contraindications

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Dosage form: & nbspdrops for oral administration

Composition:

1 ml of the preparation contains:

ethyl bromizovaleric acid (ethyl bromoisovalerianate) (in terms of 100% substance) - 20 mg, phenobarbital - 18.26 mg, peppermint mint oil (mint oil) - 1.42 mg;

Excipients: ethanol 96% (rectified ethyl alcohol) - 0.58 ml, sodium isovalerianate (in terms of dry matter) - 0.2 mg, purified water up to 1 ml.

Description:A clear, colorless liquid with a specific odor.

Pharmacotherapeutic group:The sedative

ATX: & nbsp

Other sleeping pills and sedatives

Pharmacodynamics:

Combined drug, the effect of which is due to the properties of its constituents substances. Has a sedative and spasmolytic effect. Facilitates the onset of natural sleep.

Ethyl ester of alpha-bromoisovaleric acid has a sedative (like the effect of valerian) and spasmolytic action due to irritation mainly of the oral cavity and nasopharynx, a decrease in reflex excitability in the central parts of the nervous system and an increase in inhibition in neurons of the cortex and subcortical structures of the brain, as well as a decrease in the activity of the central vasomotor centers and direct local antispasmodic action on smooth muscles.

Phenobarbital strengthens the sedative effect of other components, helps reduce excitation of the central nervous system and facilitates the onset of sleep.

Mint oil pepper has a reflex vasodilating, spasmolytic, mild choleretic, antiseptic action. The mechanism of action is associated with the ability to irritate the "cold" receptors of the oral mucosa and reflexively expand primarily the vessels of the heart and brain. Eliminates the phenomena of flatulence due to irritation of the receptors of the mucous membrane of the gastrointestinal tract, strengthening the peristalsis of the intestine.

Pharmacokinetics:No data available.

Indications:

Corvalol is prescribed as a soothing and vasodilating agent in functional disorders of the cardiovascular system, neurosis-like conditions, accompanied by increased irritability, disturbed sleep, tachycardia, arousal state with pronounced vegetative manifestations, and as an antispasmodic agent - with spasms of the intestine.

Contraindications:

Hypersensitivity to the components of the drug; expressed violations of kidney and / or liver function, lactation period (if necessary, the appointment during the period of feeding should decide whether to stop breastfeeding), pregnancy.

Pregnancy and lactation:

Do not use during pregnancy and during lactation.

Dosing and Administration:

Dosage is set individually.

Inside before eating, previously dissolved in a small amount (30-50 ml) of water, 2-3 times a day. A single dose, if necessary (for example, with tachycardia) can be increased to 40-50 drops.

Children - 3-15 caps / day (depending on the age and clinical picture of the disease). Duration of the drug is determined by the doctor individually.

Side effects:

Drowsiness, dizziness, slow heart rate, decreased ability to concentrate, allergic reactions.

With long-term admission - the phenomenon of bromism, addiction, drug dependence, withdrawal syndrome.

If any of the side effects listed in the manual are aggravated, or if you notice any other side effects not listed in the instructions, tell your doctor.

Overdose:

Symptoms: depression of the central nervous system, nystagmus, ataxia, lowering of arterial pressure, violations of the blood formula, excitation, chronic intoxication with bromine (depression, apathy, rhinitis, conjunctivitis, hemorrhagic diathesis,violation of coordination of movements).

Treatment: symptomatic, with the suppression of the central nervous system - caffeine, nikethamide.

Interaction:

Drugs that depress the central nervous system, enhance the effect.

Phenobarbital (inductor of microsomal oxidation) can reduce the effectiveness of drugs metabolized in the liver (including coumarin derivatives, griseofulvin, glucocorticosteroids. oral contraceptives); strengthens the action of local anesthetic, analgesic and hypnotic drugs.

Effect on the ability to drive transp. cf. and fur:The preparation contains 58% by volume of ethanol and phenobarbital, so patients who are taking Corvalol are not recommended to engage in activities associated with increased attention and requiring rapidity of mental and motor reactions.

Form release / dosage:Drops for oral administration.

Packaging:

To 25 ml in bottles of dark glass ukuporennyh stoppers, droppers and caps screwed or caps screw-capping with the control of the first opening, or lids for vials with a dropper, with the control of the first autopsy.

Each bottle is placed in a pack of cardboard along with instructions for use.

Storage conditions:

Store in a dark place at a temperature of no higher than 25 ° C.

Keep out of the reach of children.

Shelf life:

2 years and 6 months.

Do not use after expiry date.

Terms of leave from pharmacies:Without recipe

Registration number:П N014513 / 01

Date of registration:31.10.2008 / 24.08.2017

Expiration Date:Unlimited

The owner of the registration certificate:FARMAK, PAO FARMAK, PAO Ukraine

Manufacturer: & nbsp

FARMAK, PAO Ukraine

Representation: & nbspFARMAK PAOFARMAK PAO

Information update date: & nbsp18.01.2018

Illustrated instructions

Instructions

Corvalol (Corvalol)