Kudesan for children - instructions for use, doses, side effects, contraindications

Active substanceUbidecarenoneUbidecarenone

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Kudesan® for children

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RUSFIK, LLC Russia

Dosage form: & nbspchewing tablets

Composition:

Active substance: ubedecarenone 7.5 mg (in the All-Kew substance (Coenzyme Q10) 10% TG / P 75.0 mg).

Excipients: dextrose monohydrate 856.0 mg, povidone 10.0 mg, silicon colloidal dioxide 15.0 mg, croscarmellose sodium 10.0 mg, talc 20.0 mg, magnesium stearate 10.0 mg, cream flavor 4.0 mg. Weight of the tablet is 1000 mg.

Description:Round flat cylindrical tablets of white color with a cream shade with orange impregnations.

Pharmacotherapeutic group:Cardiotonic agent of non-glycosidic structure

ATX: & nbsp

C.01.E.X Other combination drugs for the treatment of heart disease

C.01.E.X.09 Ubidecarenone

Pharmacodynamics:Ubidecarenone (coenzyme Q10, ubiquinone) is a natural substance that is a vitamin-like coenzyme. Ubidecarenone is an endogenous substrate, takes part in the transfer of electrons in the transport chain of oxidation-reduction processes, in the process of energy exchange, in the reaction of oxidative phosphorylation in the respiratory chain of mitochondria of cells. Participates in the processes of cellular respiration, increasing the synthesis of adenosine triphosphate (ATP).Has a clinically significant antioxidant effect. Protects the lipids of cell membranes from peroxidation. Reduces the area of damage to the myocardium under conditions of ischemia and reperfusion. Ubidecarenone prevents the elongation of the QT-interval, improves the tolerance of exercise. Due to endogenous synthesis 100% satisfaction of the body's need for coenzyme Q10 occurs only up to the age of 20 years. Endogenous synthesis of coenzyme Q10 decreases with various diseases in both adults and children, as well as in the elderly.

Indications:In children from 3 years of age:

As part of complex therapy chronic heart failure, dilated cardiomyopathy, arrhythmias; chronic gastroduodenitis; migraine, neurocirculatory dystonia, hereditary neurodegenerative diseases (mitochondrial encephalomyopathy (MELAS-syndrome), tuberous sclerosis); chronic pyelonephritis, metabolic nephropathy; congenital myopathies, muscular dystrophies, diseases associated with metabolic disorders (asthenic syndrome, recovery period after severe diseases and surgical interventions).
The period of preparation for heart operations (congenital and acquired defects) is as prescribed by the doctor.
To improve the adaptation to increased physical exertion in athletes.
For prevention and replacement of coenzyme Q10 deficiency.

Contraindications:

Children under 3 years old,
hypersensitivity to the components of the drug,
acute glomerulonephritis,
exacerbation of peptic ulcer of stomach and duodenum.

Carefully:Arterial hypotension.

Pregnancy and lactation:The drug is not recommended for pregnant and lactating women due to lack of sufficient clinical experience.

Dosing and Administration:The drug "Kudesan® for children" should be taken orally once a day during meals in the morning.
For the purpose of preventing and replenishing the deficiency of coenzyme Q10, take in accordance with the recommendations set out in Table 1.

Table 1

Age	Number of tablets, average appointments	Equivalent content of coenzyme Q10
3 years - 7 years	1 tablet	7.5 mg
7-12 years old	1-2 tablets	7.5-15 mg
Children over 12 years and adults	2-4 tablets	15-30 mg

In the complex therapy of various diseases, the drug "Kudesan® for children" is taken depending on the age for all declared indications in accordance with the recommendations set forth in Table 2.

table 2

Age	Number of tablets, average appointments	Equivalent content of coenzyme Q10
3 years - 7 years	2-3 tablets	15-22.5 mg
7-12 years old	3-4 tablets	22.5-30 mg

Children older than 12 years and adults for use in complex therapy of diseases recommended the use of the drug "Kudesan®", drops for oral administration of 3%.

The duration of the course of application of the drug "Kudesan® for children" is 2-3 months. Repeated courses - on the advice of a doctor.

Side effects:Allergic reactions are possible. Very rarely: nausea, diarrhea.

Overdose:Cases of drug overdose are not described.

Interaction:

Simultaneous use of lipid-lowering agents (statins, fibrates), beta-blockers (atenolol, metoprolol, propranolol), tricyclic antidepressants can lead to a decrease in the concentration of ubidecarenone in the blood plasma. Ubidecarenone can reduce the effect of warfarin.

Ubidecarenone can potentiate the action of nitrates, enhance the antihypertensive effect of diltiazem, metoprolol.

Effect on the ability to drive transp. cf. and fur:The effect of the drug "Kudesan® for children" on the ability to drive vehicles and work with mechanisms has not been studied.

Form release / dosage:Chewable tablets 7.5 mg.

Packaging:

For 10, 12, 15 tablets in a contour mesh box made of PVC film and aluminum foil printed lacquered.

1, 2, 3, 4 contour squares, together with instructions for use, are placed in a pack of cardboard.

Storage conditions:

Store in a dark place at a temperature of 4 to 25 ° C.

Keep out of the reach of children.

Shelf life:

2 years.

Do not use after expiry date.

Terms of leave from pharmacies:Without recipe

Registration number:LP-001101

Date of registration:03.11.2011 / 30.07.2015

Expiration Date:03.11.2016

The owner of the registration certificate:RUSFIK, LLC RUSFIK, LLC Russia

Manufacturer: & nbsp

VNESHTORG PHARMA, LLC Russia

Representation: & nbspRUSFIK LLC RUSFIK LLC Russia

Information update date: & nbsp06.02.2018

Illustrated instructions

Instructions

Kudesan® for children (Kudesan® for children)