Active substanceLactulose + Lignin hydrolysisLactulose + Lignin hydrolysis
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  • Lactofiltrum®
    pills inwards 
    AVVA RUS, OJSC     Russia
  • Dosage form: & nbsppills
    Composition:

    For one tablet:

    Lignin hydrolyzed (in terms of dry matter) - 355 mg.

    Lactulose (in terms of 100 % substance) 120 mg.

    Excipients:

    Sodium croscarmellose - 20 mg.

    Magnesium stearate - 5 mg.

    Cellulose microcrystalline - until pills with a mass of 550 mg.

    Description:Tablets of dark brown color with white-gray impregnations, a capsular-shaped biconvex form with a risk.
    Pharmacotherapeutic group:Enterosorbent
    ATX: & nbsp

    A.06.A.D   Laxative preparations with osmotic properties

    A.06.A.D.61   Lactulose in combination with other drugs

    Pharmacodynamics:

    Pharmacological action of the drug is due to the properties that make up the active ingredients - lignin and lactulose.

    Lignin hydrolyzed - a natural enterosorbent, consisting of products of hydrolysis of wood components, has a high sorption activity and nonspecific detoxification action. Binds in the intestines and removes from the body pathogenic bacteria and bacterial toxins, drugs, heavy metal salts, alcohol, allergens and also the excess of some metabolic products, including bilirubin, cholesterol, histamine, serotonin, urea, other metabolites responsible for the development of endogenous toxicosis.

    Not toxic, not absorbed, completely eliminated from the intestine within 24 hours. Lactulose - a synthetic disaccharide whose molecule consists of the remains of galactose and fructose. Lactulose in the stomach and upper intestine is not; It is absorbed and not hydrolyzed. Released from tablets lactulose in the large intestine as a substrate is fermented by normal intestinal microflora, stimulating the growth of bifidobacteria and lactobacilli. As a result of hydrolysis of lactulose in the large intestine, organic acids are formed, lactic, acetic and ant which inhibit the growth of pathogenic microorganisms and thereby reduce the production of nitrogen-containing toxic substances. The described process leads to an increase in osmotic pressure in the lumen of the large intestine and stimulation of peristalsis. The complex effect of the drug is aimed at normalizing the large intestine microbiocenosis and reducing the intensity of endogenous toxic conditions. The use of the drug in the complex therapy of bacterial vaginosis (dysbiosis of the vagina) leads to an increase in the effectiveness of therapy, including,an increase in the number of lactobacilli in the vagina, as well as an effective suppression of the growth of the opportunistic flora.

    Indications:

    Disturbances of intestinal microflora (intestinal dysbacteriosis), including as a result of antibiotic therapy; in the complex therapy of irritable bowel syndrome, hepatitis and cirrhosis; allergic diseases (atopic dermatitis, urticaria), bacterial vaginosis (dysbiosis of the vagina).

    Contraindications:

    Individual intolerance of the drug, intestinal obstruction, gastrointestinalbleeding, galactosemia. It is undesirable to use the drug for exacerbation of gastric ulcer and duodenal ulcer, atony of the intestine.

    Dosing and Administration:

    Dosing and Administration Inside, if necessary after preliminary grinding, with water, an hour before meals and taking other medicines.

    With intestinal dysbiosis:

    - adults and children over 12 years - 2-3 tablets 3 times a day,

    - Children from 8 to 12 years - 1-2 tablets, 3 times a day,

    - children from 3 to 7 years - 1 tablet, 3 times a day,

    - children from 1 year to 3 years - 1/2 tablet, 3 times a day.

    With bacterial vaginosis (dysbiosis of the vagina):

    2 tablets 3 times a day.

    The average duration of treatment is 2-3 weeks.

    Long-term use of the drug and repeated courses of treatment should be carried out only on the advice of a doctor.
    Side effects:

    There may be allergic reactions to the components of the drug, rarely - flatulence.

    Overdose:

    Symptoms: constipation, abdominal pain.

    Treatment: discontinuation of the drug.

    Interaction:It is possible to reduce the therapeutic effect of some simultaneously taken drugs.
    Special instructions:

    The drug can be used in complex therapy in conjunction with other medicines, subject to the rule of separate admission.

    Form release / dosage:

    Pills.

    Packaging:

    For 10 or 15 tablets in a contour mesh box made of polyvinylchloride film and aluminum foil printed lacquered. For 30 or 60 tablets in a plastic bottle with a screw cap or in a polymer can with a screw cap.

    For 1, 2, 3 or 6 out-of-round cell packs of 10 tablets, 2 or 4 contour packs of 15 tablets or 1 bottle or 1 can, together with the instructions for use, are placed in a pack of cardboard.
    Storage conditions:

    In a place protected from moisture and light at a temperature not exceeding 30 ° C.

    Keep out of the reach of children.

    Shelf life:3 years. Do not use the drug after the expiration date.
    Terms of leave from pharmacies:Without recipe
    Registration number:LSR-008904/08
    Date of registration:11.11.2008 / 16.01.2018
    Expiration Date:Unlimited
    The owner of the registration certificate:AVVA RUS, OJSC AVVA RUS, OJSC Russia
    Manufacturer: & nbsp
    Information update date: & nbsp10.02.2018
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