Levomekol® (Levomecol®)

Composition Pharmacodynamics Indications Carefully Contraindications Dosing and Administration Side effects Form release / dosage
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Active substanceDioxomethyltetrahydropyrimidine + ChloramphenicolDioxomethyltetrahydropyrimidine + Chloramphenicol
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  • Levomekol®
    ointment locally 
    Nizhny Novgorod Chemical and Pharmaceutical Plant, OJSC    
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    ointment externally 
    GREEN DUBRAVA, CJSC     Russia
  • Levomicon-TFF
    ointment externally 
    TULA PHARMACEUTICAL FACTORY, LTD.     Russia
    • Dosage form: & nbsp

    ointment for external use

    Composition:

    For 1 g of the drug:

    active ingredients - dioxomethyltetrahydropyrimidine (methyluracil) 40 mg, chloramphenicol - 7.5 mg;

    Excipients - macrogol-1500 - 190.5 mg, macrogol-400 - 762 mg.

    Description:

    Ointment is white or white with a yellowish hue.

    Pharmacotherapeutic group:Antimicrobial medication combined
    ATX: & nbsp

    D.06.C   Antibiotics in combination with other antimicrobials

    Pharmacodynamics:

    Combined drug for topical application, has anti-inflammatory (dehydrating) and antimicrobial effect, is active against gram-positive and gram-negative microorganisms (staphylococci, Pseudomonas aeruginosa and Escherichia coli). Easily penetrates into the tissues without damage to biological membranes, stimulates regeneration processes. In the presence of pus and necrotic masses, antibacterial action persists.

    Indications:

    Purulent wounds (incl.infected with mixed microflora) in the first (purulent-necrotic) phase of the wound process.

    Contraindications:Hypersensitivity to the components of the drug; Children under 1 year of age (in newborns, the biotransformation of chloramphenicol takes place more slowly than in adults).
    Pregnancy and lactation:

    Use during pregnancy is possible only if the benefit to the mother exceeds the risk to the fetus.

    During lactation, either stop using the drug or breast-feeding.
    Dosing and Administration:

    Locally. The preparation is impregnated with sterile gauze wipes, which loosely fill the wound. Possible introduction into the purulent cavity through the catheter (drainage tube) with a syringe. In this case, the ointment is preheated to 35-36 ° C. Dressings are performed daily, once a day, until the wound is completely cleared of purulent necrotic masses. At large wound surfaces, the daily dose of ointment in terms of chloramphenicol should not exceed 3 g. The duration of treatment depends on the severity and course of the disease.

    Side effects:

    Allergic reactions (skin rashes).

    Overdose:

    No cases of overdose of Levomekol® ointment were reported.

    Interaction:Cases of interaction or incompatibility with other drugs are not described.
    Effect on the ability to drive transp. cf. and fur:

    He does not.

    Form release / dosage:

    Ointment for external use.

    Packaging:

    By 30 g, 40 g or 50 g in tubes aluminum or tuba polyethylene laminated.

    Each tube together with the instructions for medical use of the drug is placed in a pack of cardboard.

    Storage conditions:

    At a temperature not exceeding 20 ° C.

    Keep out of the reach of children place.

    Shelf life:3 years 6 months. Do not use the drug after the expiration date.
    Terms of leave from pharmacies:Without recipe
    Registration number:P N003107 / 01
    Date of registration:17.11.2009 / 10.07.2014
    Expiration Date:Unlimited
    The owner of the registration certificate:Nizhny Novgorod Chemical and Pharmaceutical Plant, OJSCNizhny Novgorod Chemical and Pharmaceutical Plant, OJSC
    Manufacturer: & nbsp
    Information update date: & nbsp11.03.2018
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