During clinical trials in men and women 12-71 years, most often (≥1 / 100, <1/10), the following side effects occurred: headache, drowsiness, dryness of the oral mucosa, fatigue; infrequently (≥1 / 1000, <1/100) there were asthenia and abdominal pain.
During clinical trials in children aged 6 to 12 years, most often (≥1 / 100, <1/10) there was a headache and drowsiness.
During the post-marketing use of the drug, the following side effects were observed, the frequency of which is unknown due to insufficient data:
From the immune system: hypersensitivity reactions, including anaphylactic shock.
From the central nervous system: headache, drowsiness, fatigue, seizures, aggression, agitation, tremor, anxiety, insomnia, hallucinations, depression, suicidal thoughts, paresthesia, dizziness, fainting, dysgeusia (dyspnea), thrombosis of the dura mater.
From the sense organs: impaired vision, vertigo, blurred vision, inflammatory manifestations.
From the cardiovascular system: heart palpitations, angina pectoris, tachycardia, jugular vein thrombosis.
From the digestive system: dryness of the oral mucosa, pain in the abdomen, nausea, vomiting.
From the liver and bile ducts: hepatitis.
From the urinary system: dysuria, urinary retention.
From the skin and soft tissues: angioedema, persistent drug erythema, pruritus, rash, hives, hypotrichosis, cracks,photosensitization.
From the side of the musculoskeletal and connective tissue: muscle pain.
From the respiratory system: shortness of breath, increased symptoms of rhinitis.
From the side of metabolism: weight gain.
Other: asthenia, increased appetite, cross-reactivity, peripheral edema.
Laboratory indicators: increased activity of "liver" transaminases.
If any of the side effects listed in the manual are aggravated, or if you notice any other side effects not listed in the instructions, tell your doctor.