For oral administration. The drug should be taken with food or on an empty stomach. The required number of drops should be measured with a dropper in a tablespoon or a glass of water. Drops should be taken orally immediately after dilution. The daily dose is recommended at one time.
The recommended dose for adults and children over 6 years old, elderly patients (subject to normal kidney function) is 5 mg (1 ml drops or 20 drops from a dropper) per day.The maximum daily dose should not exceed 5 mg.
Children aged 2 to 6 years - the daily recommended dose is 2.5 mg for two doses in equal doses of 1.25 mg (2 times 0.25 ml drops = 2x5 drops from the dropper). The maximum daily dose should not exceed 2.5 mg.
Patients with impaired renal function
The frequency of admission should be set individually according to the function of the kidneys. In patients with chronic renal failure with creatinine clearance (CK) from 30 to 49 ml / min, the dose should be reduced 2 times (5 mg (1 ml drops or 20 drops from a dropper) every other day); with SC from 10 to 29 ml / min dose should be reduced 3 times (5 mg (1 ml drops or 20 drops from the dropper) every 3 days). In severe renal failure (CC less than 10 ml / min), the drug is contraindicated.
Patients with impaired hepatic function
When prescribing the drug to patients with an isolated impairment of liver function, no dose changes are required. Patients with combined disorders of the liver and kidneys are recommended dose adjustment (see the section "Patients with impaired renal function" above).
Duration of the drug
Duration of admission depends on the disease.
In the treatment of persistent allergic rhinitis (symptoms <4 days / 1 week or less than 4 weeks), treatment is continued until symptoms disappear; If symptoms appear, treatment can be resumed. In the treatment of seasonal allergic rhinitis (symptoms> 4 days / 1 week or longer than 4 weeks) treatment continues throughout the exposure period of allergens.
The course of treatment is determined by a doctor, on average, it is 1-6 weeks.
In chronic diseases (year-round rhinitis, chronic idiopathic urticaria), the course of treatment can be longer in agreement with the doctor. There is a clinical experience of using the drug for up to 6 months.