Locally anesthetic for use in ophthalmology.
The local anesthetic effect of lidocaine is due to the blockade of potential-dependent sodium channels, which prevents the generation of pulses in the endings of the sensory nerves and pain impulses along nerve fibers.
Lidocaine eliminates the pain sensitivity of the cornea, but complete (deep) anesthesia of the cornea (with complete shutdown of tactile, temperature and pressure sensitivity) is usually not achieved.
After installation into the conjunctival sac, the local anesthetic effect is achieved in 2-3 minutes and lasts no less than 6-8 minutes (usually up to 10-15 minutes). The onset of anesthesia is 1 min after the installation.Maximum anesthesia is usually achieved approximately 5 minutes after the installation.