Active substanceLidocaineLidocaine
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  • Dosage form: & nbspeye drops
    Composition:

    Active substance: lidocaine hydrochloride monohydrate (in terms of lidocaine hydrochloride) - 20.0 mg.

    Excipients: benzethonium chloride (benzethonium chloride) - 0.02 mg, sodium chloride - 6.0 mg, water for injection, up to 1 ml.

    Description:Transparent colorless or slightly colored liquid.
    Pharmacotherapeutic group:Local anesthetic
    ATX: & nbsp

    N.01.B.B   Amides

    N.01.B.B.02   Lidocaine

    C.01.B.B.01   Lidocaine

    C.01.B.B   Antiarrhythmic drugs Ib class

    Pharmacodynamics:

    Locally anesthetic for use in ophthalmology.

    The local anesthetic effect of lidocaine is due to the blockade of potential-dependent sodium channels, which prevents the generation of pulses in the endings of the sensory nerves and pain impulses along nerve fibers.

    Lidocaine eliminates the pain sensitivity of the cornea, but complete (deep) anesthesia of the cornea (with complete shutdown of tactile, temperature and pressure sensitivity) is usually not achieved.

    After installation into the conjunctival sac, the local anesthetic effect is achieved in 2-3 minutes and lasts no less than 6-8 minutes (usually up to 10-15 minutes). The onset of anesthesia is 1 min after the installation.Maximum anesthesia is usually achieved approximately 5 minutes after the installation.

    Indications:

    Local anesthesia in ophthalmology:

    - when conducting contact research methods (tonometry, gonioscopy, diagnostic scrapings of the cornea);

    - with short-term surgical interventions on the cornea and conjunctiva (including the extraction of a foreign body, suture material from the cornea or conjunctiva);

    - when preparing for ophthalmological operations.

    Contraindications:Hypersensitivity to lidocaine or other components of the drug.
    Carefully:Children's age, pregnancy, lactation.
    Pregnancy and lactation:

    Adequate controlled studies in pregnant and lactating women have not been conducted.

    The use of lidocaine in pregnant women did not lead to an increase in the incidence of fetal developmental disorders. However, the risk can not be ruled out completely. In this regard, caution should be exercised when prescribing lidocaine during pregnancy, especially in the first trimester. It is not recommended to breast-feed during the application of the drug.

    Dosing and Administration:Locally, by installing into the conjunctival sac immediately before the test or surgery, 1-2 drops 2-3 times at intervals of 30-60 seconds.
    Side effects:

    Local allergic reactions, conjunctival hyperemia, burning sensation, during installation, headache.

    If any of the side effects indicated in the manual are aggravated, or if you notice any other side effects not listed in the instructions, tell your doctor!

    Overdose:No relevant data are available.
    Interaction:No relevant data are available.
    Special instructions:

    During the action of the drug, do not touch the eyes.

    Before digging in eye drops contact lenses should be removed; You can insert the lenses not earlier than 30 minutes after instillation.

    Effect on the ability to drive transp. cf. and fur:If the side effects after the use of the drug do not cause discomfort, restrictions on the management of vehicles, mechanisms and occupations of other hazardous activities requiring special attention and rapid reactions there.
    Form release / dosage:
    Eye drops 2%.
    Packaging:

    To 5 ml in bottles with plugs-droppers and screw-on caps made of plastic.

    Each bottle with instructions for use in a pack of cardboard.

    Storage conditions:

    In the dark place at a temperature of 15 to 25 ° C.

    Keep out of the reach of children.

    Shelf life:After opening the vial, use within 1 month. Do not use after the expiration date printed on the package.
    Terms of leave from pharmacies:On prescription
    Registration number:P N000439 / 01
    Date of registration:01.08.2011 / 01.06.2016
    Expiration Date:Unlimited
    The owner of the registration certificate:SYNTHESIS, OJSC SYNTHESIS, OJSC Russia
    Manufacturer: & nbsp
    Information update date: & nbsp27.02.2018
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