Lipoic acid - instructions for use, dose, side effects, contraindications

Excipients of the core tablet: sugar (sucrose) 52.917 mg or 105.22 mg, glucose (dextrose) 21.3 mg or 41.7 mg, potato starch 10.1 mg or 20.7 mg, calcium 1-water stearate (calcium stearate monohydrate) 0.5 mg or 1.0 mg, stearic acid 0.5 mg or 1.0 mg, talc (magnesium hydrosilicate) 2.5 mg or 5.0 mg.

Shell accessories: aerosil (silicon dioxide colloidal) 0.77 mg or 1.08 mg titanium dioxide 1.689 mg or 2.35 mg magnesium carbonate basic magnesium hydroxycarbonate 13.976 mg or 18.0 mg oil vaseline 0,014 mg or 0.02 mg, low molecular weight polyvinylpyrrolidone (povidone) 0.665 mg or 0.93 mg,sugar (sucrose) 57.6 mg or 77.24 mg, talc (magnesium hydrosilicate) 0.085 mg or 0.12 mg, dye quinoline yellow E-104 0.18 mg or 0.23 mg

Description:

Tablets are yellow or greenish-yellow, coated. Two layers are visible on the cross-section.

Pharmacotherapeutic group:Metabolic means

ATX: & nbsp

A.16.A.X.01 Thioctic acid

Pharmacodynamics:

Lipoic acid is a coenzyme involved in the oxidative decarboxylation of pyruvic acid and alpha-keto acids, plays an important role in the energy balance of the body. By the nature of biochemical action thioctic acid is similar to the vitamins of the B group. It participates in the regulation of lipid and carbohydrate metabolism, has a lipotropic effect, affects cholesterol metabolism, improves liver function, has a detoxification effect in poisoning with salts of heavy metals and other intoxications.

Indications:

Fatty degeneration of the liver, liver cirrhosis, chronic hepatitis, hepatitis A, intoxications (including heavy metal salts, pale toadstool), hyperlipidemia.

Contraindications:

Hypersensitivity, lactation period, children's age (up to 6 years).

Carefully:Pregnancy.

Dosing and Administration:

Inside after eating. Adults - 50 mg 3-4 times a day.

Children older than 6 years - 12-24 mg 2-3 times a day.

Duration of treatment is 20-30 days. If necessary, the appointment of a doctor is a repeat course of treatment after 1 month.

Side effects:

Dyspepsia (including nausea, heartburn, vomiting, diarrhea, abdominal pain), allergic reactions (including urticaria, skin rashes, itching and systemic allergic reactions right up to anaphylactic shock), hypoglycemia.

Interaction:

Enhances the anti-inflammatory effect of glucocorticosteroids. Reduces the effectiveness of cisplatin. Strengthens the action of insulin and oral hypoglycemic agents. Binds metals, therefore, should not be taken simultaneously with drugs containing metal ions (iron preparations, magnesium calcium); the interval between the reception should be at least 2 hours. Ethanol and its metabolites weaken the action of lipoic acid.

Special instructions:

During the period of treatment, regular monitoring of glucose concentration (especially at the beginning of therapy) is necessary in patients with diabetes mellitus; should refrain from drinking alcohol.

Form release / dosage:

Tablets coated with 12 mg and 25 mg.

Packaging:

10 tablets per contour cell pack.

For 50, 100 tablets in cans of glass melt or cans of polymer material.

Each jar or 5 contour squares, together with the instruction for use, is placed in a bundle.

Storage conditions:

In a dry, protected from light place at a temperature of no higher than 25 ° C.

Keep out of the reach of children.

Shelf life:

3 years. Do not use after the expiry date printed on the package.

Terms of leave from pharmacies:On prescription

Registration number:P N001574 / 01

Date of registration:10.05.2007

Expiration Date:Unlimited

The owner of the registration certificate:MARBIOFARM, OJSC MARBIOFARM, OJSC Russia

Manufacturer: & nbsp

MARBIOFARM, OJSC Russia

Representation: & nbspMARBIOFARM, OJSCMARBIOFARM, OJSC

Information update date: & nbsp10.04.2018

Illustrated instructions

Instructions

Lipoic acid (Lipoic acid)