Lomefloxacin
From the digestive system: nausea, vomiting, dry mouth, gastralgia, abdominal pain, diarrhea, constipation, flatulence, pseudomembranous enterocolitis, dysphagia, discoloration of the tongue, decreased appetite, bulimia, taste distortion, dysbiosis, increased hepatic transaminase activity, bleeding from the digestive tract.
From the central nervous system and peripheral nervous system: fatigue, malaise, asthenia, headache, dizziness, fainting, insomnia, hallucinations, convulsions, hyperkinesia, tremor, paresthesia, nervousness, anxiety, depression, arousal.
On the part of the genitourinary system: glomerulonephritis, dysuria, polyuria, anuria, albuminuria, bleeding from the urethra, crystalluria, hematuria, urinary retention, edema; in women - vaginitis, leukorrhea, intermenstrual bleeding, pain in the perineum, vaginal candidiasis; in men - orchitis, epididymitis.
From the side of metabolism: hypoglycemia, gout.
From the musculoskeletal system: arthralgia, spasms of the calf muscles, pain in the back and chest area.
On the part of the organs of hematopoiesis: thrombocytopenic purpura, increased fibrinolysis.
On the part of the respiratory system: dyspnoea, respiratory infections, bronchospasm, cough, hypersecretion of phlegm, flu-like syndrome, epistaxis.
From the senses: visual impairment, pain and noise in the ears, pain in the eyes.
From the cardiovascular system: lowering blood pressure, tachycardia, bradycardia, extrasystole, arrhythmias, progression of heart failure and angina, pulmonary embolism, myocardiopathy, phlebitis.
Allergic reactions: itching, hives, malignant exudative erythema (Stevens-Johnson syndrome).
Influence on the fetus: fetotoxic action (arthropathy).
Other: candidiasis, increased sweating, chills, thirst, reinfection, lymphadenopathy, photosensitivity.
Prothionamide
On the part of the digestive system: nausea, vomiting, diarrhea, hypersalivation, "metallic" taste in the mouth, impaired liver function.
From the central nervous system and peripheral nervous system: insomnia, agitation, depression, anxiety, dizziness, drowsiness, headache, asthenia, paresthesia, peripheral neuropathy, optic neuritis.
From the cardiovascular system: tachycardia, weakness, orthostatic hypotension.
Allergic reactions: skin rash.
Other: hypoglycemia (in patients with diabetes mellitus), gynecomastia, dysmenorrhea, hypothyroidism, decreased potency.
Pyrazinamide
On the part of the digestive system: nausea, vomiting, diarrhea, a "metallic" taste in the mouth, a decrease in appetite, a violation of liver function, liver tenderness, hepatomegaly, jaundice, yellow liver atrophy, exacerbation of peptic ulcer.
From the central nervous system and peripheral nervous system: dizziness, headache, sleep disturbances, increased excitability, depression; hallucinations, convulsions, confusion.
From the hematopoiesis: thrombocytopenia, sideroblastic anemia, erythrocyte vacuolization, porphyria, hypercoagulation, splenomegaly.
From the musculoskeletal system: arthralgia, myalgia.
From the side of the urinary system: dysuria, interstitial nephritis.
Allergic reactions: skin rash, hives.
Other: hyperthermia, acne, hyperuricemia, exacerbation of gout, photosensitivity, increased serum iron concentration.
Ethambutol
From the side of the central nervous system and peripheral nervous system: weakness, headache, dizziness, impaired consciousness, disorientation, hallucinations, depression, peripheral neuritis (paresthesia in the extremities, numbness, paresis, itching), optic neuritis (decreased visual acuity), impaired color perception (green and red colors), color blindness, scotoma.
On the part of the digestive system: decreased appetite, nausea, vomiting, gastralgia, impaired liver function, increased activity of hepatic transaminases.
Allergic reactions: dermatitis, skin rash, itching, arthralgia, fever, anaphylaxis.
Other: photosensitization, hyperuricemia, exacerbation of gout.