Mizol Evalar - instructions for use, dose, side effects, contraindications

Pharmacodynamics:Naphthyfine is an antifungal agent for external use, which belongs to the class of allylamines. The mechanism of action is associated with the inhibition of squalene-2,3-epoxidase, which leads to a decrease in the formation of ergosterol, which is part of the cell wall of the fungus. It is active against dermatophytes, such as trichophyton, epidermophyton and microsporum, mold (Aspergillus spp.), yeast fungi (Candida spp.. Pityrosporum) and other fungi (for example, Sporothrix schenckii). For dermatophytes and aspergillas naphthyline is fungicidal. With regard to yeast fungi, the preparation shows fungicidal or fungistatic activity, depending on the strain of the microorganism. Has antibacterial activity against Gram-positive and gram-negative microorganisms that can cause secondary bacterial infections. Has an anti-inflammatory effect, which contributes to the rapid disappearance of symptoms of inflammation, especially itching.

Pharmacokinetics:

With external application naphthyline quickly penetrates the skin, creating stable antifungal concentrations in its various layers, which makes it possible to use it once a day.

Indications:

- Fungal infections of skin and skin folds (tinea corporis, tinea inguinalis);

- interdigital mycoses (tinea manum, tinea pedum);

- fungal infections of nails (opyhomycosis);

- candidiasis of the skin;

- multicolored (lichen);

- dermatomycosis (with or without accompanying itching).

Contraindications:

Hypersensitivity to naphthyfin or propylene glycol.

Pregnancy and the period of breastfeeding (safety and efficacy not established).

Contraindicated application of the drug on the wound surface.

Carefully:

Children's age (clinical experience is limited).

Pregnancy and lactation:

The use of Mizol® Evalar during pregnancy and during breastfeeding is contraindicated (the safety and effectiveness of naphthyfine in this category of patients has not been studied).

Dosing and Administration:

Outwardly.

Mizol® Evalar is applied once a day to the affected skin and adjacent areas (approximately 1 cm of healthy skin around the edges of the affected area) after thorough cleaning and drying. Duration of therapy with dermatomycosis - 2-4 weeks (if necessary - up to 8 weeks), with candidiasis - 4 weeks.

When the nails are affected Mizol® Evalar is applied 2 times a day to the affected nail. Before the first use of the drug, remove the affected part of the nail with scissors or a nail file. The duration of therapy with onychomycosis is up to 6 months.

To prevent recurrence, treatment should be continued for at least 2 weeks after the disappearance of clinical symptoms.

If there is no improvement after treatment or new symptoms appear, it is necessary to consult a doctor.Use the drug only according to the method of administration and the doses specified in the instructions. If necessary, please consult with your doctor before using the medication.

Side effects:

In some cases, local reactions can occur: dry skin, skin hyperemia and burning. Side effects are reversible and do not require withdrawal of treatment. If you experience side effects indicated in the instructions or are aggravated, or if you notice any other side effects not listed in the instructions, tell your doctor.

Overdose:

When using the drug in accordance with the instructions for use, an overdose is unlikely. At casual intake is shown gastric lavage, symptomatic therapy.

Interaction:

Interaction with other drugs has not been studied.

Special instructions:

The drug Misol® Evalar is not intended for use in ophthalmology. Do not allow the product to enter the eyes.

To achieve a therapeutic effect, course treatment is required.

Mizol® Evalar is effective in the treatment of mycosis, affecting the skin area with hyperkeratosis, as well as in areas of hair growth.

Propylene glycol, which is part of the solution, can cause skin irritation; If side effects occur, discontinue use and consult a doctor.

Effect on the ability to drive transp. cf. and fur:

Mizol® Evalar does not affect the performance of potentially hazardous activities requiring increased concentration and speed psychomotor reactions.

Form release / dosage:

Solution for external use 1%.

Packaging:

For 10, 20 ml in bottles-droppers from brown or orange glass for medicines, ukuporennye stoppers-droppers and caps screwed with the control of the first autopsy.

To 50 ml in bottles of brown or orange glass for medicines, sealed with traffic jams and caps screwed with the control of the first autopsy.

Each vial or dropper along with the instruction for use is placed in a pack of cardboard.

Storage conditions:At a temperature of no higher than 25 ° C. Keep out of the reach of children.

Shelf life:

3 years. Do not use after the expiration date.

Terms of leave from pharmacies:Without recipe

Registration number:LP-004445

Date of registration:01.09.2017

Expiration Date:01.09.2022

The owner of the registration certificate:EVALAR, CJSC EVALAR, CJSC Russia

Manufacturer: & nbsp

EVALAR, CJSC Russia

Information update date: & nbsp21.11.2017

Illustrated instructions

Instructions

Mizol® Evalar (Mizol Evalar)