Timolol - instructions for use, dose, side effects, contraindications

A non-selective β-adrenoreceptor blocker when inserted into the conjunctival sac inhibits the adenylylcyclase ciliary tissue system that transports sodium ions from the blood into the intraocular fluid, which leads to a decrease in intraocular pressure.

Does not affect the refraction, accommodation and the size of the pupil.

Pharmacokinetics:

After the installation in the conjunctival sac, the therapeutic effect develops after 1-2 hours and lasts for 8-24 hours.

Absorption into the total blood flow is insignificant - the drug does not have a systemic effect.

Indications:

It is used for the treatment of glaucoma and with an acute increase in ophthalmotonus.

ICD-10

VII.H40-H42.H40.0 Suspicion of glaucoma

VII.H40-H42.H40.1 Primary open angle glaucoma

VII.H40-H42.H40.2 Primary angle-closure glaucoma

VII.H40-H42.H40.3 Glaucoma secondary posttraumatic

VII.H40-H42.H40.4 Glaucoma secondary due to inflammatory disease of the eye

VII.H40-H42.H40.5 Glaucoma secondary due to other eye diseases

Contraindications:

Dystrophy of the cornea, atrophic rhinitis, sinus bradycardia, severe heart failure, individual intolerance.

Carefully:

Pregnancy and lactation.

Pregnancy and lactation:

Recommendations for FDA - Category B. It is used in pregnancy and lactation.

Dosing and Administration:

Installation in the conjunctival cavity 1 drop 2 times / day.

The highest daily dose: 1 drop.

The highest single dose: 2 drops.

Side effects:

Reducing tear, "dry eye syndrome."

Allergic reactions.

Overdose:

Cases of overdose are not described.

Treatment is symptomatic.

Interaction:

To enhance the effect and duration of the drug, a combination with pilocarpine, carbonic anhydrase inhibitors, adrenomimetics and taufon is possible.

Special instructions:

Persons using contact eye correction should remove their lenses before installing the drug and dress no earlier than 15 minutes.

Instructions

Timolol (Timololum)