Undesirable reactions that occur after ingestion of timolol and other beta-blockers can be regarded as potential adverse reactions and for eye-level drugs timolol in the form of a drug.
The most common adverse reactions are burning and tingling after instillation (approximately in 1/8 of patients).
Described below are undesirable reactions that occurred with a lower frequency in patients using timolol eye forms.
General reactions and reactions at the site of administration: headache, asthenia / fatigue, chest pain.
Cardiovascular system: bradycardia, arrhythmia, decreased or increased blood pressure, fainting, heart block, cerebral circulation, cerebral ischemia, heart failure, exacerbation of angina pectoris tension, palpitations, cardiac arrest, pulmonary edema, edema, intermittent claudication, Raynaud's phenomenon, coldness of the hands and feet.
On the part of the digestive system: nausea, diarrhea, dyspepsia, anorexia, dryness of the oral mucosa.
On the part of the immune system: systemic lupus erythematosus.
From the nervous system / mental disorders: dizziness, exacerbation of myasthenia gravis flow, paresthesia, drowsiness, insomnia, nightmares, behavioral changes and mental disorders, including depression, confusion, hallucinations, anxiety, disorientation, nervousness and memory loss.
From the skin and subcutaneous tissues: alopecia, psoriasiforme rash, aggravation of the course of psoriasis.
Allergic reactions: systemic allergic reactions, including anaphylaxis, angioedema, hives, local or generalized rash.
On the part of the respiratory system: bronchospasm (mainly in patients with concomitant bronchospastic conditions), respiratory failure, shortness of breath, nasal congestion, cough, upper respiratory tract infections.
On the part of the endocrine system: the subclinical course of hypoglycemia in patients with diabetes mellitus (see section "Special instructions").
From the senses: eye irritation, including conjunctivitis, blepharitis, keratitis, pain in the eye, discharge from the eyes (eg, peel), sensation of foreign body in the eye, itching and lacrimation, dry eyes; ptosis; decreased sensitivity of the cornea; cystic macular edema; visual impairment, including refraction and diplopia; pseudopemphigoid; detachment of the choroid after filtration surgery (see section "Special instructions"); noise in ears.
From the genitourinary system: retroperitoneal fibrosis, decreased libido, impotence, Peyronie's disease.
Undesirable drug reactions that occurred after taking tgsholol or other beta-adrenoblockers orally
Allergic reactions: erythematous rash, fever, accompanied by pain in the throat, laryngospasm, accompanied by a distress syndrome.
General reactions and reactions at the injection site: pain in the limbs, reduced exercise tolerance, weight loss.
From the cardiovascular system: aggravation of arterial insufficiency, vasodilation.
On the part of the digestive system: gastrointestinal pain, hepatomegaly, vomiting, thrombosis of the mesenteric arteries, ischemic colitis.
From the side of blood and lymphatic system: non-morbocytopenic purpura, thrombocytopenic purpura.
On the part of the endocrine system: hyperglycemia, hypoglycemia.
From the skin and subcutaneous tissues: itching, skin irritation, increased pigmentation, sweating.
From the musculoskeletal system: arthralgia.
From the nervous system / mental disorders: vertigo, local weakness, decreased concentration of attention, reversible suppression of mental functions, progressing to catatonia, acute reversible syndrome,characterized by a violation of orientation in time and space, emotional lability, some difficulty in perception and a reduced ability to perform neuropsychiatric tests.
From the respiratory system, wheezing, bronchial obstruction.
From the genitourinary system, difficulty urinating.