Ramni - instructions for use, dose, side effects, contraindications

Active substanceCalcium carbonate + Magnesium carbonateCalcium carbonate + Magnesium carbonate

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Ramni®

pills inwards

TATHIMFARMPREPARATY, JSC Russia

Rennie®

pills locally inwards

BAYER, AO Russia

Rennie®

pills locally inwards

BAYER, AO Russia

Dosage form: & nbspTablets are chewable.

Composition:

1 tablet contains:

Active substances: calcium carbonate - 680 mg, magnesium carbonate (magnesium carbonate basic) - 80 mg;

Excipients: mannitol, povidone (kollidone 90 F), sucrose, orange flavor, sodium stearyl fumarate, talc.

Description:

Round, flat-cylindrical white or white tablets with a cream color shade, with a reinforced bevel, without risks, with the smell of orange. Allowed light marble and minor inclusions.

Pharmacotherapeutic group:antacid agent

ATX: & nbsp

A.02.A.X Antacids in combination with other drugs

Pharmacodynamics:

The drug Ramni ® contains antacid substances - calcium carbonate and magnesium carbonate, which provide rapid and prolonged neutralization of excess hydrochloric acid of gastric juice, thereby providing a protective effect on the gastric mucosa. Achieving a positive effect within 3-5 minutes is due to the good solubility of the tablets and the high calcium content.

Pharmacokinetics:

As a result of the interaction of the drug Ramni ® with gastric juice in the stomach, soluble salts of calcium and magnesium are formed. The level of absorption of calcium and magnesium from these compounds depends on the dose of the drug. Maximum absorption level - 10% calcium and 15-20% magnesium. A small amount of absorbed calcium and magnesium is excreted through the kidneys. If the renal function is impaired, the level of calcium and magnesium concentration in the plasma may increase. In the intestine, soluble salts form insoluble compounds that are excreted with feces.

Indications:

Symptoms associated with high acidity of gastric juice and reflux esophagitis: heartburn, acidic eructation, periodic pain in the stomach, feeling of overflow or heaviness in the epigastric region, dyspepsia (including those caused by inaccuracies in diet, medication, alcohol abuse, coffee , nicotine), dyspepsia of pregnant women.

Contraindications:

Severe renal failure, hypercalcemia, hypophosphatemia, nephrocalcinosis, hypersensitivity to drug components, sugarase / isomaltase deficiency, fructose intolerance, glucose-galactose malabsorption, children under 12 years.

Pregnancy and lactation:

When used in recommended doses, the drug does not pose a hazard to the fetus or the baby.

Dosing and Administration:

Inside.

Adults and children over 12 years of age: if the doctor is not recommended otherwise, when symptoms appear, 1-2 tablets chew (or keep in your mouth until completely dissolved). If necessary, you can repeat the drug after 2 hours.

The maximum daily dose is 11 tablets.

Side effects:

When the recommended doses are observed, the drug is well tolerated, however, in very rare cases, allergic reactions are possible: rash, Quincke's edema, anaphylactic reactions.

Overdose:

Prolonged use of the drug in high doses in patients with impaired renal function can cause hypermagnesemia, hypercalcemia, alkalosis, which can be manifested by nausea, vomiting, muscle weakness. In this case, you should cancel the drug and immediately consult a doctor.

Interaction:

Changing the acidity of gastric juice, during the use of antacids, can lead to a decrease in the rate and extent of absorption of other drugs, while taking, so drugs should be taken 1-2 hours before or after taking antacid preparations.

Antibiotics of the tetracycline series, fluoroquinolones, cardiac glycosides, levothyroxine, iron preparations, fluorides, phosphates - with simultaneous use of antacids reduce the absorption of these drugs.

Thiazide diuretics - while concomitant administration with antacids should regularly monitor the concentration of calcium in the blood serum.

Special instructions:

When appointing the drug, patients with impaired renal function should regularly monitor the concentration of magnesium, phosphorus and calcium in the blood serum.

Patients with impaired renal function are not recommended to take the drug for a long time in high doses.

The use of Ramni ® in high doses can increase the risk of kidney stones.

Indication for patients with diabetes: 1 tablet of Ramni ® contains 295.3 mg of sucrose (0.03 XE).

If the drug is not effective, you should consult your doctor for advice.

Effect on the ability to drive transp. cf. and fur:

The use of the drug does not affect the ability to perform potentially hazardous activities requiring increased concentration and speed of psychomotor reactions (driving,work with moving mechanisms, the work of the dispatcher and the operator).

Form release / dosage:Tablets are chewable.

Packaging:

6 or 10 tablets per contour cell package.

1 or 2 contour squares, together with instructions for use, are placed in a pack of cardboard.

Storage conditions:At a temperature of no higher than 25 ° C.

Keep out of the reach of children.

Shelf life:

3 years.

Do not use after expiry date.

Terms of leave from pharmacies:Without recipe

Registration number:LP-003793

Date of registration:18.08.2016

Expiration Date:18.08.2021

The owner of the registration certificate:TATHIMFARMPREPARATY, JSC TATHIMFARMPREPARATY, JSC Russia

Manufacturer: & nbsp

TATHIMFARMPREPARATY, JSC Russia

Representation: & nbspTATHIMFARM PREPARATIONS OJSC TATHIMFARM PREPARATIONS OJSC Russia

Information update date: & nbsp09.10.2016

Illustrated instructions

Instructions

Ramni® (Ramni®)