Rederm - instructions for use, doses, side effects, contraindications

Combination drug for external use, the effect of which is due to its constituent components; the drug has anti-inflammatory, anti-allergic, antipruritic, keratolytic action.

Betamethasone inhibits the release of mediators of inflammation, prevents the accumulation of neutrophils, reduces inflammatory exudate and production of cytokines, reduces the migration of macrophages, leading to a reduction in infiltration and granulation.

Thanks to the availability salicylic acid softens the skin, eliminates horny layers and promotes deeper penetration of betamethasone.

Indications:

Rederm is indicated for use in the treatment of subacute and chronic dermatoses accompanied by hyperkeratosis and desquamation: psoriasis, dyshidrotic dermatitis, eczema, neurodermatitis, lichen planus, ichthyosis and ichthyosis skin lesions, atopic dermatitis, diffuse neurodermatitis; simple and allergic dermatitis; urticaria, multiforme exudative erythema; simple chronic lichen (limited neurodermatitis).

Dermatoses that are not amenable to treatment with other glucocorticosteroids (especially red warty lichen), skin dyshidrosis.

Contraindications:

Children under 2 years old, lactation period, hypersensitivity, open wounds, bacterial, viral and fungal skin diseases (pyoderma, syphilis, skin tuberculosis, chicken pox, herpes,actinomycosis, blastomycosis, sporotrichosis); postvaccinal skin reactions, perioral dermatitis, rosacea, trophic ulcers on the background of chronic venous insufficiency, skin tumors (skin cancer, nevus, atheroma, epithelioma, melanoma, hemangioma, xanthoma, sarcoma).

Carefully:

Hepatic insufficiency, children's age (over 2 years), long-term therapy, especially with the use of occlusive dressings.

Pregnancy and lactation:

The safety of the use of local glucocorticosteroids in pregnant women is not established. The appointment of this group of drugs during pregnancy is justified only if the potential benefit to the mother exceeds the potential risk to the fetus. During pregnancy, drugs of this group should not be used in high doses or for a long time.

It has not been established whether the local use of glucocorticosteroids can cause them to appear in the mother's milk, so the question of stopping breastfeeding should be addressed.

Dosing and Administration:

Outwardly. Apply to affected areas at the rate of: a column of ointment 0.5 cm long on a skin area of about 7 cm x 7 cm, slightly rubbing,thin layer 2 times a day.

Another frequency of use can be determined by the doctor, based on the severity of the disease.

In light cases, the ointment is sufficient to apply, as a rule, once a day; with more severe lesions may need more frequent use.

If necessary, impose occlusive dressings, which are changed every 24 hours.

The duration of treatment depends on the effectiveness and tolerability of therapy and is 2-4 weeks.

If clinical improvement does not occur, it is necessary to clarify the diagnosis.

Side effects:

Burning, irritation, dryness, hypopigmentation, skin itching, folliculitis, hypertrichosis, dermatitis, acne-like rashes.

When using occlusive dressings - Maceration of the skin, striae, skin atrophy, secondary infection, sweating.

With prolonged use - skin atrophy, local hirsutism, telangiectasia, purpura, hypopigmentation, hypertrichosis.

When applied to large surfaces - Systemic manifestations of side effects of glucocorticosteroids (growth retardation, Itenko-Cushing syndrome, increased intracranial pressure after treatment, hyperglycemia, glucosuria, hypokalemia,increased blood pressure) or salicylates (pallor, fatigue, drowsiness, hyperventilation against tachypnea, nausea, vomiting, hearing impairment, confusion).

Overdose:

Acute overdose is unlikely, however, with excessive or prolonged use of the drug, a chronic overdose is possible, accompanied by signs of hypercorticoidism: hyperglycemia, glucosuria, reversible suppression of adrenal cortex function, manifestation of Cushing's syndrome.

Treatment. The corresponding symptomatic treatment was shown. In the case of chronic toxic effects, a gradual withdrawal of the drug is recommended.

Interaction:

Interactions of the drug with other drugs have not been identified.

Special instructions:

Avoid contact with the eyes, do not apply to the skin near the eyes and mucous membranes. The drug is not intended for use in ophthalmology.

With prolonged treatment, when applying the drug on the vast surface of the skin, with the use of occlusive dressings, systemic absorption of glucocorticosteroids is possible.

It is not recommended for long-term use on the skin of a person - it is possible to develop dermatitis by the type of rosacea, perioral dermatitis, atrophy of the skin and acne; avoid application in the anogenital area.

Ointment is most suitable for the treatment of patients with dry and fragile skin.

If there are signs of increased sensitivity or skin irritation associated with the use of the drug, you should stop treatment and choose the patient adequate therapy.

With prolonged use of the drug, it should be canceled gradually.

Pediatric Use

Children from 2 years of age, the drug is prescribed only under strict indications and under medical supervision, since it is possible to develop systemic side effects associated with betamethasone. The duration of treatment should be as short as possible. When applying the drug on large surfaces and / or under the occlusive dressing, it is possible to suppress the function of the hypothalamic-pituitary-adrenal system and the development of symptoms of hypercorticism, a decrease in the excretion of growth hormone, an increase in intracranial pressure can be observed.

Form release / dosage:

Ointment for external use.

Packaging:

For 5 g, 15 g or 30 g in aluminum tubes.

Each tube together with the instruction for use is placed in a pack of cardboard.

Storage conditions:

In a place inaccessible to children, at a temperature of no higher than 25 ° C.

Shelf life:

2 years.

Do not use after expiry date.

Terms of leave from pharmacies:Without recipe

Registration number:LSR-000865/10

Date of registration:10.02.2010

The owner of the registration certificate:VERTEKS, AO VERTEKS, AO Russia

Manufacturer: & nbsp

ALTAYVITAMINS, CJSC Russia

Representation: & nbspVERTEKS CJSC VERTEKS CJSC Russia

Information update date: & nbsp20.11.2015

Illustrated instructions

Instructions

Rederm® (Rederm®)