Ringer lactate - instructions for use, dose, side effects, contraindications

Active substanceSodium lactate solution is complex [Potassium chloride + Calcium chloride + Sodium chloride + Sodium lactate]Sodium lactate solution is complex [Potassium chloride + Calcium chloride + Sodium chloride + Sodium lactate]

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Dosage form: & nbspsolution for infusions

Composition:

Active substances:

Sodium chloride - 6.00 g

Potassium chloride - 0.40 g

Calcium chloride hexahydrate - 0.27 g
(in terms of anhydrous)

Sodium lactate - 3.20 g

Excipients: Water for Injection - up to 1.0 liter

Ionic composition (per 1 liter):

Sodium - ion - 131.0 mmol

Potassium ion - 5.4 mmol

Calcium ion - 1.8 mmol

Chloride ion - 106.3 mmol

Lactate ion - 28.5 mmol

Theoretical osmolality 273 mOsmol / l

Description:

Transparent colorless liquid.

Pharmacotherapeutic group:electrolyte balance is a restoring agent.

ATX: & nbsp

B.05.B.B.01 Electrolytes

Pharmacodynamics:

Rehydrating agent, has a detoxification effect Replenishes the deficiency of the volume of circulating blood, stabilizes the water and electrolyte composition of the blood.Normalizes the acid-base state. Lactate is metabolized in the body to bicarbonate, therefore the solution has alkalizing effect. The solution is close to isotonic, osmolarity is 273 mOsmol / l.

Pharmacokinetics:

Indications:

Hypovolemia, isotonic dehydration, metabolic acidosis.

Contraindications:Hypersensitivity, hypervolemia, hypertonic dehydration, hyperkalemia, hypernatremia, arterial hypertension, cardiac and / or renal insufficiency, hyperchloremia, alkalosis, hepatic insufficiency (decrease in the formation of bicarbonate from lactate), hyperlactacidemia.

Carefully:Respiratory failure, acute dehydration, simultaneous treatment with glucocorticoid agents.

Pregnancy and lactation:

During pregnancy, apply in cases where the expected benefit to the mother exceeds the risk to the fetus. During lactation should refrain from breastfeeding.

Dosing and Administration:

Intravenously drip at a rate of 60 drops / min. At urgent conditions - 180 drops / min, in volume, depending on the patient's condition. Adults median daily dose - 1 liter, children - 20-30 ml / kg. The maximum daily dose is 2.5 liters.

Side effects:

Thrombophlebitis, hypervolemia, hyperhydration, hyperchloremia, anxiety, allergic reactions.

Overdose:not described

Interaction:

Nonsteroidal anti-inflammatory drugs, androgens, anabolic steroids, estrogens, corticotropin, mineral corticosteroids, vasodilators and ganglion blockers increase the risk of hypernatremia; potassium-sparing diuretics, drugs K + - hypercapia. The drug becomes alkaline and inhibits the excretion of drugs that have an alkaline reaction. Accelerates excretion Li+ and salicipates.

Special instructions:

It is necessary to conduct a regular blood test to determine electrolytes, pH and partial pressure of CO2, the volume of circulating blood.

Effect on the ability to drive transp. cf. and fur:not described

Form release / dosage:

Solution for infusion.

200 or 400 ml in glass bottlesMTO brand for blood, transfusionand infusion drugs250, or 450 ml ofdirectly.

1 bottle with instructions for medical application is placed in a pack of cardboard.

For 28 bottles with a capacity of 250 or 15, bottles with a capacity of 450 ml with an equal number of instructions for medical use is placed in boxes of cardboard (for hospitals).

Packaging:bottles for blood and blood substitutes (1) -tacks, cardboard
bottles for blood and blood substitutes (1) - cardboard tacks (15)
bottles for blood and blood substitutes (1) -package cardboard (28)
bottles for blood and blood substitutes (15) - cardboard boxes
bottles for blood and blood substitutes (28) - cardboard boxes

Storage conditions:In the dark place at a temperature of no higher than 25 ° C. Keep out of the reach of children.

Shelf life:

2 years. Do not use after the expiration date printed on the package.

Terms of leave from pharmacies:On prescription

Registration number:LSR-005650/09

Date of registration:14.07.2009

The owner of the registration certificate:ESKOM NPK, OAO ESKOM NPK, OAO Russia

Manufacturer: & nbsp

ESKOM NPK, OAO Russia

Information update date: & nbsp30.06.2011

Illustrated instructions

Instructions

Ringer lactate (Ringer lactici)