Сималгел -ВМ (Simalgel-BM)

Composition Pharmacodynamics Indications Carefully Contraindications Dosing and Administration Side effects Form release / dosage
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Active substanceAlgealdrate + Magnesium hydroxide + SimethiconeAlgealdrate + Magnesium hydroxide + Simethicone
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    World Medical Co., Ltd.     Egypt
    • Dosage form: & nbsporal suspension
    Composition:

    Per 1 ml of the preparation:

    Active substances: aluminum hydroxide (as a dry gel) - 81 mg, magnesium hydroxide - 20 mg, simethicone - 25 mg.

    Excipients:

    citric acid 0.60 mg, peppermint mint oil 0.13 mg, mannitol 2.50 mg, sodium methylparahydroxybenzoate 1.00 mg, sodium propyl parahydroxybenzoate 0.50 mg, sodium saccharinate 0.28 mg, sorbitol (solution 10%) - 14.00 mg, hydrogen peroxide concentrated - 1.22 mg, ethanol 96% - 0.5 mg, purified water - up to 1 ml.
    Description:Homogeneous homogeneous suspension of milky white or almost white with a minty smell. When standing, it is a layered suspension: the bottom layer is a dense white precipitate, the upper layer - almost transparent liquid, on the surface of which there is a translucent gelatinous formation of white-color. With shaking, the homogeneity of the suspension is restored.
    Pharmacotherapeutic group:Antacid agent + carminative agent
    ATX: & nbsp

    A.02.A.F   Antacids in combination with drugs that reduce gassing in the intestine

    Pharmacodynamics:SIMALGEL-VM - a combined tool, the effect of which is due to its constituent components; has antacid, adsorbing, enveloping and carminative effect. Algehydrate (aluminum hydroxide) and magnesium hydroxide neutralize free hydrochloric acid in the stomach, reduce the acidity of the gastric juice, bind bile acids. The relaxing effect of magnesium hydroxide balances the ability of the algebra to slow bowel motility. Simethicone complicates the formation of gas bubbles and contributes to their destruction. The gases released in this way are absorbed by the walls of the intestine and are excreted from the body by peristalsis.
    Pharmacokinetics:

    Absorption is low.

    Indications:

    Diseases of the gastrointestinal tract (GIT), accompanied by flatulence:

    acute gastritis;

    - Hyperacid gastritis;

    acute duodenitis;

    - peptic ulcer of the stomach and duodenum (in the phase of exacerbation);

    - symptomatic gastrointestinal ulcers of different genesis;

    - erosion of the mucous membrane of the upper gastrointestinal tract;

    - hernia of the esophageal aperture of the diaphragm;

    - reflux esophagitis;

    And also can be used for gastrointestinal discomfort, gastralgia, heartburn (after excessive consumption of alcoholic beverages, nicotine, coffee, taking medicines, inaccuracies in the diet).

    Contraindications:

    Hypersensitivity to the components of the preparation Simalgel-VM, pronounced impairment of kidney function (due to the danger of increasing the concentration of magnesium and aluminum ions in the blood serum, due to a slowing of their release by the kidneys), hypophosphatemia; Alzheimer's disease, sugar / isomaltase deficiency, fructose intolerance, glucose-galactose malabsorption, children under 10 years old.

    Carefully:Use with caution in pregnancy and during lactation, liver disease, alcoholism, craniocerebral trauma, brain diseases, epilepsy, children 10 to 18 years of age.
    Pregnancy and lactation:

    The use of the drug during pregnancy and during breastfeeding is possible only if the intended benefit to the mother exceeds the potential risk to the fetus or child. When taking the drug during lactation, termination of breastfeeding is not required.

    Dosing and Administration:

    Suspension for oral administration.

    Adults take p10 ml 4 times a day 1 hour after meals (if not indicated by the doctor otherwise). The maximum daily dose is 40 ml of the preparation of Simalgel-BM (treatment course - no more than 2 weeks when used in maximum doses).

    When reflux-esophagitis the drug is taken a short time after eating 5-10 ml 4 times a day. The course of treatment should not exceed 2-3 months (with maximum doses - no more than 2 weeks).

    With episodic use (heartburn, gastrointestinal discomfort with malnutrition) - once 10 ml.


    For children older than 10 years, the dosage is determined by the attending physician (usually 1/2 dose for adults).
    The maximum daily dose is 20 ml of the preparation of Simalgel-BM (treatment course - no more than 2 weeks when used in maximum doses).
    Side effects:

    Allergic reactions, intestinal colic. With long-term administration in therapeutically high doses - hypophosphatemia, hypocalcemia, hypercalciuria, osteomalacia, osteoporosis, hypermagnesia, hyperaluminia, encephalopathy, nephrocalcinosis, impaired renal function. In patients with renal insufficiency, it is possible to develop aluminum, magnesium intoxication, thirst, lowering blood pressure, hyporeflexia.Exacerbation of osteoarthritis and Alzheimer's disease (in the elderly). On the part of the gastrointestinal tract may be a violation of taste, nausea, vomiting, diarhea, constipation.

    Overdose:

    Symptoms: Signs of metabolic alkalosis (mood changes, numbness or pain in muscles, nervousness, fatigue, unpleasant taste sensations).

    Treatment: stimulation of vomiting, gastric lavage, intake of activated carbon.
    Interaction:Reduces and slows down the absorption of digoxin, indomethacin, salicylates, chlorpromazine, phenytoin, H2-histamine receptor blockers, beta-adrenoblockers, diflunisal, ketoconazole and itraconazole, isoniazid, tetracycline antibiotics and quinolones, azithromycin; cefpodoxime, pivapicillin, rifampicin, indirect anticoagulants, barbiturates, fexofenadine; dipyridamole, zalcitabine, chenodeoxycholic and ursodeoxycholic acid, penicillamine and lansoprazole. M-holinoblokatory, slowing the emptying of the stomach, strengthen and lengthen the action of the drug.
    Special instructions:

    Before use, the vial with suspension should be well shaken!

    When joint application of Simalgel-BM and other drugs, the interval between the intake should be at least 2 hours. With special caution appoint patients with impaired renal function, liver and elderly patients - appointment in this case is carried out under control of the attending physician.

    With prolonged use of the drug, it is recommended to monitor the content of phosphorus and magnesium in the blood.

    In one dose of the drug (10 ml) contains 0.0048 g of ethyl alcohol (in terms of absolute alcohol).

    Effect on the ability to drive transp. cf. and fur:Does not adversely affect the ability to drive vehicles and work with mechanisms that require increased concentration and speed of psychomotor reactions.
    Form release / dosage:

    Suspension for oral administration.

    Packaging:125 ml, 300 ml of the drug in vials of dark glass. One bottle with dosed cap together with instructions for use in a cardboard pack.
    Storage conditions:

    In a dry and dark place at a temperature of no higher than 25 ° C.

    After opening the vial, the drug should be used within 28 days.

    Keep out of the reach of children.

    Shelf life:

    3 years.

    Do not use after the expiration date.
    Terms of leave from pharmacies:Without recipe
    Registration number:LP-001657
    Date of registration:17.04.2012
    The owner of the registration certificate:World Medical Co., Ltd.World Medical Co., Ltd. Egypt
    Manufacturer: & nbsp
    Representation: & nbspTROKAS PHARMA LLCTROKAS PHARMA LLCRussia
    Information update date: & nbsp17.08.2015
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