Sonnovan® (Sonnovan)

Classification of the incidence of side effects in accordance with the recommendations of the World Health Organization: very often (≥ 1/10), often (from ≥ 1/100 to <1/10), infrequently (from ≥1 / 1000 to <1/100), rarely (from ≥1 / 10000 to <1/1000) , very rarely (<1/10000), including individual messages; frequency is unknown (according to available data, it is not possible to establish the frequency of occurrence).

Infectious and parasitic diseases:

rarely: herpes zoster.

Violations of the blood and lymphatic system:

rarely: leukopenia, thrombocytopenia.

Immune system disorders:

frequency unknown: hypersensitivity reactions.

Disorders from the metabolism and nutrition:

rarely: hypertriglyceridemia, hypokalemia, hyponatremia.

Disorders of the psyche:

infrequently: irritability, nervousness, anxiety, insomnia, unusual dreams, nightmares, anxiety;

rarely: mood changes, aggression, agitation, tearfulness, stress symptoms, disorientation, early morning awakening, increased libido, decreased mood, depression.

Disturbances from the nervous system:

infrequently: migraine, headache, lethargy, psychomotor hyperactivity, dizziness, drowsiness;

rarely: fainting, memory impairment, impaired concentration, delirium, restless legs syndrome, poor sleep quality, paresthesia.

Disturbances on the part of the organ of sight:

rarely: decreased visual acuity, blurred vision, increased lacrimation.

Hearing disorders and labyrinthine disorders:

rarely: vertigo, positional vertigo.

Disorders from the cardiovascular system:

infrequently: arterial hypertension;

rarely: angina pectoris, palpitations, hot flashes.

Disorders from the gastrointestinal tract:

infrequently: abdominal pain, abdominal pain in the upper abdomen, dyspepsia, ulcerative stomatitis, dry mouth, nausea;

rarely: gastroesophageal disease, gastrointestinal disturbance or disorder, bullous stomatitis, ulcerous glossitis, vomiting, increased peristalsis, bloating,hypersecretion of saliva, unpleasant odor from the mouth, abdominal discomfort, dyskinesia of the stomach, gastritis.

Disturbances from the liver and bile ducts:

infrequently: hyperbilirubinemia.

Disturbances from the skin and subcutaneous tissues:

infrequently: dermatitis, sweating at night, itching and generalized itching, rash, dry skin;

rarely: eczema, erythema, hand dermatitis, psoriasis, generalized rash, itching rash, nail damage;

frequency unknown: Quincke's edema, edema of the oral mucosa, edema of the tongue.

Disturbances from musculoskeletal and connective tissue:

infrequently: pain in the limbs;

rarely: arthritis, muscle spasm, pain in the neck, nocturnal cramps.

Disorders from the kidneys and urinary tract:

infrequently: glycosuria, proteinuria;

rarely: polyuria, hematuria, nocturia.

Violations of the genitals and the breast:

infrequently: menopausal symptoms;