Benzalkonium chloride - instructions for use, dose, side effects, contraindications

It has bactericidal activity against gram-positive (streptococcus, staphylococcus, etc.) and Gram-negative (Pseudomonas aeruginosa, E. coli, Klebsiella, Proteus, etc.) bacteria. Active with respect to virus Herpes simplex type 2, Neisseria gonorrhoeae, Staphylococcus aureus, Chlamydia spp., Trichomonas vaginalis; does not affect Mycoplasma spp. Has a weak effect on Gardnerella vaginalis, Haemophilus ducreyi, Treponema pallidum and Candida albicans.

Has a contraceptive effect, does not change the normal microflora of the vagina and the hormonal cycle of a woman.

Pharmacokinetics:

The drug for topical application does not have a systemic effect.

Indications:

It is used for the prevention of sexually transmitted infections, secondary infection of wounds. Used to treat wounds, drainage of bone cavities in osteomyelitis. It is used for the treatment of superficial thermal burns, long-lasting non-healing wounds of soft tissues. Used as a local contraceptive and for disinfection of medical devices, as well as premises.

ICD-10

XI.K55-K63.K62.8 Other specified diseases of anus and rectum

XII.L80-L99.L98.4 Chronic skin ulcer, not elsewhere classified

XII.L80-L99.L99 * Other lesions of the skin and subcutaneous tissue in diseases classified elsewhere

XIII.M86-M90.M86 Osteomyelitis

XIX.T08-T14.T14.1 Open wound of unspecified area of the body

XIX.T20-T32.T30 Thermal and chemical burns, unspecified

XIX.T79.T79.3 Post-traumatic wound infection, not elsewhere classified

XXI.Z30-Z39.Z30.0 General advice and advice on contraception

Contraindications:Contact dermatitis, malignant neoplasms of the skin; for intravaginal application - colpitis, ulceration and irritation of the mucous membrane of the vagina and uterus.

Individual intolerance.

Carefully:

Hypersensitivity.

Pregnancy and lactation:

Recommendations for FDA - Category C. Contraindicated in pregnancy and lactation.

Dosing and Administration:

For topical application: 1% solution impregnate gauze bandages, tampons or napkins and superimpose on the wound. Dressings are performed daily for 14 days.

The maximum daily dose: 50 g.

Intravaginal: deep in the vagina before intercourse.

Liquid concentrate is used for disinfection of premises, after dilution with water.

Side effects:

Contact dermatitis, vulvovaginitis, candidiasis, allergic reactions.

Overdose:

Cases of overdose are not described.

Treatment is symptomatic.

Interaction:

Inactivate the action of the drug any medicinal substances introduced into the vagina, as well as iodine preparations, soap, shampoo and other hygiene products containing detergents and actively surface substances.

Special instructions:

The effectiveness of the contraceptive effect of the drug is low, to a greater extent, it is used to prevent sexually transmitted infections.

Instructions

Benzalkonium chloride (Benzalkonii chloridum)