Cream TRIDERM® is not intended for use in ophthalmology.
Prolonged local use of antibiotics can sometimes lead to an increase in resistant microflora. In this case, as well as with the development of irritation, sensitization or superinfection during the treatment with TRIDERM® cream, treatment should be discontinued and appropriate therapy prescribed.
There were cross-allergic reactions with aminoglycoside antibiotics.
Any side effects that occur in the use of systemic SCS, including oppression of adrenal cortex function, can be noted even with local application of GCS, especially in children.
Systemic absorption of GCS or gentamicin for topical application will be higher if treatment is performed on large areas of the skin or with the use of occlusive dressings, especially with prolonged treatment or in violation of the integrity of the skin. It is necessary to avoid applying gentamicin to open wounds and damaged skin. Otherwise, there may be side effects, characteristic of gentamicin in its systemic application. Appropriate precautions should be taken in such cases, especially when treating children.
With prolonged use of the drug, it is recommended to abolish it gradually.
Pediatric Use
For children, the drug is prescribed only on strict indications and under medical supervision. systemic side effects associated with the use of local corticosteroids, they can develop more often than in adult patients. Such side effects include: suppression of the hypothalamic-pituitary-adrenal system; Cushing's syndrome; growth retardation; slowing of weight gain; increased intracranial pressure, manifested by bulging fontanelles, headache, bilateral edema of the optic disc.