Zinocap® (Cinocap®)

Composition Pharmacodynamics Indications Carefully Contraindications Dosing and Administration Side effects Form release / dosage
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Active substanceZinc pyrithioneZinc pyrithione
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    • Dosage form: & nbspAerosol for external use .
    Composition:

    Composition per cylinder

    When packing the drug 35 g: active substance: pyrithione zinc (in terms of 100% substance) - 0.060 g; auxiliary substances: sodium lauryl sulfate 0.030 g, isopropyl myristate 20.214 g, silicon dioxide colloid (aerosil) 0.453 g, dexpanthenol (D-Panthenol) 0.181 g, polysorbate 80 (tween 80) 0.151 g, ethanol 70% ethyl alcohol 70%) - 9,081 g, tetrafluoroethane (chladone 134a) - up to 35,000 g.

    When packing the drug at 58 g: the active substance: pyrithione zinc (in terms of 100% substance) - 0.100 g; auxiliary substances: sodium lauryl sulfate 0.050 g, isopropyl myristate 33,500 g, silicon dioxide colloid (aerosil) 0.750 g, dexpanthenol (D-Panthenol) 0.300 g, polysorbate 80 (tween 80) 0.250 g, ethanol 70% ethyl alcohol 70%) - 15,050 g, tetrafluoroethane (chladone 134a) - up to 58,000 g.

    Description:

    Oily liquid from white to light yellow with a specific odor.

    Pharmacotherapeutic group:Dermatoprotective agent.
    ATX: & nbsp

    D.11.A.X.12   Zinc pyrithione

    Pharmacodynamics:

    Pyrithione zinc has anti-inflammatory, antibacterial and antifungal activity.Antibacterial activity of zinc pyrithione is manifested in a number of Gram-positive and Gram-negative bacteria (Streptococcus spp., Staphylococcus spp., Escherichia coli, Pseudomonas aeruginosa, Proteus spp.). Pyrithione zinc reduces the intracellular level of ATP, contributes to the depolarization of cell membranes, causing the death of fungi and bacteria. Antifungal activity is especially pronounced against fungi of the genus Malassezia (formerly Pityrosporum ovale and Pityrosporum orbiculare), causing inflammation and excessive desquamation in dandruff, seborrheic dermatitis, psoriasis and other skin diseases. The mechanism of anti-inflammatory action has not been studied.

    Pharmacokinetics:

    With external use, pyrithione zinc is deposited in the epidermis and the surface layers of the dermis. Systemic absorption is negligible. The drug is found in the blood in trace amounts.

    Indications:

    • psoriasis
    • atopic dermatitis (eczema, neurodermatitis)
    • seborrheic dermatitis

    Contraindications:

    Hypersensitivity, children under 1 year.

    Dosing and Administration:

    The drug is intended for external use.

    Applied in adults and children from 1 year. Before use, shake the can. Spray the drug on the affected skin from a distance of 15 cm 2-3 times a day until the clinical effect is achieved.For the preparation of the scalp, an additional nozzle is attached. It is advisable to continue the use of the drug within one week after the disappearance of the symptoms.

    Duration of treatment with:

    • psoriasis 1-1,5 months, repeated courses - with the appearance of signs of exacerbation;
    • Atopic dermatitis 3-4 weeks;
    • seborrheic dermatitis 2 weeks.

    Side effects:

    The drug is usually well tolerated. Rarely, allergic reactions. In the first days of treatment, there may be a brief burning sensation in the place of application, which, as a rule, does not require its cancellation.

    Overdose:

    To date, no cases of overdose of zinc pyrithione have been reported.

    Interaction:

    Clinically significant interaction of zinc pyrithione with other drugs has not been identified.

    Special instructions:

    When spraying, keep the can upright.

    Form release / dosage:

    Aerosol for external use 0,2%.

    Packaging:

    35 g or 58 grams into aerosolized aluminum cylinders equipped with continuous valves and protective caps.

    The bottle together with a spray for external use, an additional nozzle and instructions for use are placed in a pack of cardboard.

    Storage conditions:

    Store at temperatures from 4 to 30 ° C out of the reach of children.

    Shelf life:

    3 years.

    Do not use after the expiration date printed on the package.

    Terms of leave from pharmacies:Without recipe
    Registration number:LSR-010497/08
    Date of registration:24.12.2008
    The owner of the registration certificate:Otisipharm, PAO Otisipharm, PAO
    Manufacturer: & nbsp
    Information update date: & nbsp15.10.2015
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