Iodine (Iodum)

Composition Pharmacodynamics Indications Carefully Contraindications Dosing and Administration Side effects Form release / dosage
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Active substanceIodineIodine
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  • Iodine
    solution externally 
    OMSKA FARMFABRIKA, OGUP     Russia
  • Iodine
    solution externally 
    PERMFARMACY, OJSC     Russia
  • Iodine
    solution externally 
    Pharmaceutical factory of the Krasnoyarsk Territory GPP     Russia
  • Iodine
    solution externally 
    UPDATE OF PFC, CJSC     Russia
  • Iodine
    solution externally 
    KIROVSKAYA PHARMACEUTICAL COMPANY, LTD.     Russia
    • Dosage form: & nbspsolution for external use of alcohol
    Composition:

    Active substance: iodine 5 g;

    Excipients: potassium iodide 2 g, ethanol (ethyl alcohol) 95%, water purified equally to 100 ml.

    Description:Transparent liquid of red-brown color, with a characteristic smell.
    Pharmacotherapeutic group:Antiseptic
    ATX: & nbsp

    D.08.A.G.03   Iodine

    R.02.A.A   Antiseptics

    Pharmacodynamics:

    Antiseptic. The main active substance is molecular iodine, which has an antiseptic property. When applied to large areas of the skin iodine has a resorptive effect: actively affects the metabolism, enhances the processes of dissimilation, participates in the synthesis of thyroxine and triiodothyronine, has a proteolytic effect. Ethyl alcohol is a high-molecular compound that slows the excretion of iodine and reduces its irritating effect on tissues. It has a bactericidal effect, both on Gram-positive flora (most active - on streptococcal flora and Escherichia coli), as well as on pathogenic fungi and yeast.A stable flora is staphylococcus, but with prolonged use of the drug in 80% of cases it disappears. Pseudomonas aeruginosa is stable. The drug is low toxicity.

    Pharmacokinetics:

    Upon contact with the skin, it is converted into iodides by 30%, and the rest into active iodine. Partially absorbed. The absorbed part penetrates into tissues and organs, is selectively absorbed by the thyroid gland. It is allocated by kidneys (mainly), intestines, sweat and mammary glands.

    Indications:

    Inflammatory and infectious diseases of the skin, abrasions, cuts, microtrauma, wounds; myositis, neuralgia, inflammatory infiltrates; disinfection of the operating field (pre- and postoperative treatment of the operating field, injection, puncture, catheterization), the edges of wounds, the hands of the surgeon.

    Contraindications:

    Hypersensitivity, thyrotoxicosis, herpetiform dermatitis, children under 5 years.

    Carefully:

    Children under 12 years of age should avoid contact with eyes.

    Pregnancy and lactation:

    Contraindicated in pregnancy, with caution in lactation.

    Dosing and Administration:

    Outerly, the affected or treated areas of skin are smeared with a gauze pad moistened in solution.

    Side effects:

    Skin irritation, allergic reactions (itchy skin); with prolonged use on extensive surfaces - the phenomenon of iodism (rhinorrhea, bronchorrhoea, urticaria, Quincke's edema, lacrimation, hypersalivation, acne).

    Overdose:

    Symptoms: chemical burn, phenomena of iodism.

    Treatment: symptomatic: wash excess of the preparation with clean running water.

    Interaction:

    Incompatible with disinfectant medicines containing enzymes, reducing agents, alkalis; essential oils, solutions of ammonia.

    Alkaline or acidic medium, the presence of fat, pus, blood weaken antiseptic activity.

    Form release / dosage:Solution for external use alcohol, 5%.
    Packaging:

    For 10, 25 ml in bottles of orange glass, sealed with stoppers, polyethylene and screw caps. Each bottle, together with the instructions for use, is placed in a pack of cardboard.

    The full text of the instructions for use should be applied to the pack.

    Packaging of vials without a pack together with an equal number of instructions for use in group packaging is allowed.

    Storage conditions:

    In the dark place at a temperature of 0 to 25 ° C.

    Keep out of the reach of children.

    Shelf life:

    3 years.

    Do not use after the expiration date.

    Terms of leave from pharmacies:Without recipe
    Registration number:LP-001350
    Date of registration:13.12.2011
    Expiration Date:Unlimited
    The owner of the registration certificate:PERMFARMACY, OJSC PERMFARMACY, OJSC Russia
    Manufacturer: & nbsp
    Representation: & nbspPERMFARMACY, OJSCPERMFARMACY, OJSC
    Information update date: & nbsp16.11.2017
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