Iodine (Iodum)

Composition Pharmacodynamics Indications Carefully Contraindications Dosing and Administration Side effects Form release / dosage
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Active substanceIodineIodine
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  • Iodine
    solution externally 
    OMSKA FARMFABRIKA, OGUP     Russia
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    solution externally 
    PERMFARMACY, OJSC     Russia
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    solution externally 
    Pharmaceutical factory of the Krasnoyarsk Territory GPP     Russia
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    solution externally 
    UPDATE OF PFC, CJSC     Russia
  • Iodine
    solution externally 
    KIROVSKAYA PHARMACEUTICAL COMPANY, LTD.     Russia
    • Dosage form: & nbspsolution for external use [alcohol]
    Composition:

    Iodine 20 g, ethyl alcohol 96% (ethanol) to 1 liter.

    Description:Transparent liquid, red-brown color, with a characteristic odor.
    Pharmacotherapeutic group:Antiseptic
    ATX: & nbsp

    D.08.A.G.03   Iodine

    R.02.A.A   Antiseptics

    Pharmacodynamics:

    Antiseptic. The main active substance is molecular iodine, which has an antiseptic property. When applied to large areas of the skin iodine has a resorptive effect: actively affects the metabolism, enhances the processes of dissimilation, participates in the synthesis of thyroxine and triiodothyronine, has a proteolytic effect. Alcohol slows the excretion of iodine and reduces its irritating effect on tissues.

    It has a bactericidal effect on both gram-positive and gram-negative flora (most active in streptococcal flora and Escherichia coli), as well as pathogenic fungi and yeast.A more stable flora is staphylococcus, but with prolonged use of the drug in 80% of cases, staphylococcal flora is suppressed. Pseudomonas aeruginosa is stable. The drug is low toxicity.
    Pharmacokinetics:

    Upon contact with the skin, it is converted into iodides by 30%, and the rest into active iodine. Partially absorbed. The absorbed part penetrates into tissues and organs, is selectively absorbed by the thyroid gland. It is allocated by kidneys (mainly), intestines, sweat glands, with milk during lactation.

    Indications:

    Inflammatory and infectious diseases of the skin, abrasions, cuts, microtrauma, wounds; myositis, neuralgia, inflammatory infiltrates; treatment of the edges of wounds, skin before injections, punctures, catheterization.

    Contraindications:

    Hypersensitivity, thyrotoxicosis, herpetiform dermatitis.

    Dosing and Administration:

    External, lubricate the affected or subject to treatment areas of the skin.

    Side effects:Skin irritation, allergic reactions (itchy skin); with prolonged use on extensive wound surfaces - iodism (rhinitis, urticaria, Quincke's edema, salivation, lacrimation, acne).
    Overdose:

    When inhaled vapors of iodine - the defeat of the upper respiratory tract (burn, laryngobrachospasm); concentrated solutions inside - severe burns of the digestive tract, development of hemolysis, hemoglobinuria.

    For the treatment of an overdose when ingested, sodium thiosulfate in the form of a 10% solution of 2-3 g per reception.

    Interaction:

    Pharmaceutically incompatible with essential oils, solutions of ammonia, white sedimentary mercury (an explosive mixture is formed).

    Alkaline or acidic medium, the presence of fat, pus, blood weaken antiseptic activity. Weaken the hypothyroid and strugogenic effects of lithium preparations.

    Special instructions:

    Light and temperature above 40 ° C accelerate the decay of active iodine.

    The drug should have a dark brown color. Discoloration of the solution indicates the destruction of the complex with the transition of active iodine to iodide ion and a decrease in the effectiveness of the preparation.

    With compatible use with yellow mercury ointment, the formation of mercury iodide, which has a cauterizing effect, is possible.

    Form release / dosage:Solution for external use alcohol, 2%.
    Packaging:

    For 9, 18 kg in a glass bottle for hospitals.

    Storage conditions:

    In the dark place at a temperature of at least 0 ° C.

    Shelf life:

    2 months.

    Do not use after the expiry date printed on the package.

    Terms of leave from pharmacies:Without recipe
    Registration number:LSR-003066/09
    Date of registration:20.04.2009
    Expiration Date:Unlimited
    The owner of the registration certificate:KIROVSKAYA PHARMACEUTICAL COMPANY, LTD. KIROVSKAYA PHARMACEUTICAL COMPANY, LTD. Russia
    Manufacturer: & nbsp
    Representation: & nbspKIROVSKAYA PHARMACEUTICAL FACTORY, OJSCKIROVSKAYA PHARMACEUTICAL FACTORY, OJSC
    Information update date: & nbsp16.11.2017
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