Active substanceIodineIodine
Similar drugsTo uncover
  • Iodine
    solution externally 
  • Iodine
    solution externally 
    PERMFARMACY, OJSC     Russia
  • Iodine
    solution externally 
  • Iodine
    solution externally 
    UPDATE OF PFC, CJSC     Russia
  • Iodine
    solution externally 
  • Dosage form: & nbspsolution for external use [alcohol]
    Composition:

    Per 100 ml:

    active substance: iodine 5 g;

    Excipients: potassium iodide 2 g, ethanol (in terms of anhydrous anhydrous) 40.58 g, purified water until a solution with a mass of 100 g.

    Description:Transparent liquid of red-brown color with a characteristic smell.
    Pharmacotherapeutic group:Antiseptic
    ATX: & nbsp

    D.08.A.G.03   Iodine

    R.02.A.A   Antiseptics

    Pharmacodynamics:

    Antiseptic. The main active substance is molecular iodine, which has an antiseptic property. When applied to large areas of the skin iodine has a resorptive effect: it participates in the synthesis of thyroxine and triiodothyronine.

    Ethanol slows the excretion of iodine and reduces its irritating effect on tissues.

    Has a bactericidal effect on both gram-positive and gram-negative flora (most active - on Streptococcus spp. and Escherichia coli), as well as pathogenic fungi and yeast. Most strains Staphylococcus spp. are stable, however, with prolonged use of the drug in 80% of cases, staphylococcal flora is suppressed. Pseudomonas aeruginosa is stable.

    Pharmacokinetics:

    Upon contact with the skin, it is converted into iodides by 30%, and the rest into active iodine. Partially absorbed. The absorbed part penetrates into tissues and organs, is selectively absorbed by the thyroid gland. It is excreted by the kidneys (mainly), intestines, sweat glands, with breast milk during lactation.

    Indications:

    Inflammatory and infectious diseases of the skin, abrasions, cuts, microtrauma, inflammatory infiltrates; treatment of the edges of wounds, skin before injections, punctures, catheterization.

    Contraindications:

    Hypersensitivity, thyrotoxicosis, herpetiform dermatitis.

    Carefully:Childhood.
    Pregnancy and lactation:

    It is not recommended to use the drug during pregnancy. Application in the period of breastfeeding is possible if the expected benefit for the mother exceeds the potential risk for the child. It is necessary to consult a doctor.

    Dosing and Administration:

    Outwardly.

    Lubricate affected or subject to treatment areas of the skin.

    Side effects:

    Skin irritation, allergic reactions (itchy skin); with prolonged use on extensive wound surfaces - iodism (rhinitis, urticaria, Quincke's edema, excessive salivation, lacrimation, acne).

    Overdose:

    In case of an overdose, iodism, irritation and skin burns are possible.

    Treatment: symptomatic; rinse excess product with clean running water.
    Interaction:

    Pharmaceutically incompatible with essential oils, ammonia solutions, enzymes, reducing agents and alkalis, disinfecting drugs containing mercury; with white sedimentary mercury (mercury amidochloride) an explosive mixture is formed.

    Special instructions:

    Light and temperature of the environment and body above 40 ° C accelerate the decomposition of active iodine. The drug should have a dark brown color. Discoloration of the solution indicates the destruction of the complex with the transition of active iodine to iodide ion and a decrease in the effectiveness of the preparation.

    Alkaline or acidic medium, the presence of fat, pus, blood weaken antiseptic activity.

    Avoid contact with eyes.

    Effect on the ability to drive transp. cf. and fur:The use of the drug according to the instructions for medical use does not adversely affect the performance of hazardous activities requiring special attention and quick reactions.
    Form release / dosage:

    Solution for external use alcohol, 5%.

    Packaging:

    1 ml each in a dropper with a valve or 10 ml in a tube with a screw neck of high-density polyethylene or low-density polyethylene or polyethylene for medical purposes. Tube-dropper with a screw neck is capped with screw caps.

    For 10 ml in glass bottles with a screw neck type PV, sealed with caps screwed plastic with sealing elements.

    For 10 ml in glass bottles with a screw neck type PV or in bottles of glass ukuporennyh caps screwed plastic with blades.

    To 25 ml in bottles of glass with a screw neck type PV, sealed with plastic caps screw caps on plastic bottles or in bottles of polymeric polyethylene terephthalate ukuporennye screwed caps.

    For 4500 ml in polymeric bottles made of polyethylene terephthalate, sealed with screw caps.

    On a tube-droppers, bottles, stick labels or the text of a label put directly on a tube-dropper by a drop-jet printing method.

    Each bottle of 10 ml, 25 ml or 1 tube of a dropper of 10 ml or 5, 10 tubes of intravenous drip each with instructions for use is placed in a pack of cardboard for consumer containers.

    Bottles of 4500 ml, a 10 ml dropper with instructions for use are placed in a cardboard box (for hospitals).

    Vials of 10 ml, 25 ml with an equal number of instructions for use put a group package.

    Storage conditions:

    At a temperature of no higher than 25 ° C, away from fire.

    In a place inaccessible to children.

    Shelf life:

    3 years.

    Do not use after the expiration date stated on the package.

    Terms of leave from pharmacies:Without recipe
    Registration number:LS-001376
    Date of registration:09.12.2010
    Expiration Date:Unlimited
    The owner of the registration certificate:UPDATE OF PFC, CJSC UPDATE OF PFC, CJSC Russia
    Manufacturer: & nbsp
    Representation: & nbspUPDATE OF PFC, CJSCUPDATE OF PFC, CJSC
    Information update date: & nbsp16.11.2017
    Illustrated instructions
      Instructions
      Up