Pharmaceutically incompatible with drugs containing SH-gruppy.
Reduces the absorption of (mutually) antibiotics of the tetracycline group.
Antacid drugs, colloidal bismuth citrate, calcium phosphate, chloramphenicol, colestramine, Colestipol, pancreatin, Zn2+, tocopherol, vegetables, cereals, egg yolk, tea reduce the absorption of the drug; ascorbic acid increases.
Reduces the effectiveness of quinolones, levodopa, levothyroxine sodium, methyldopa, penicillin, sulfasalazine.