Betagistin - instructions for use, dose, side effects, contraindications

excipients: microcrystalline cellulose, lactose (milk sugar), citric acid monohydrate, silicon dioxide colloid (aerosil), crospovidone, talc, magnesium stearate.

Description:

Tablets are white or almost white in color, round, biconvex, with a risk on one side.

Pharmacotherapeutic group:Histamine drug

ATX: & nbsp

N.07.C.A.01 Betagistin

Pharmacodynamics:

Agonist H₁receptors of the vessels of the inner ear and antagonist H₃receptors of the vestibular nuclei of the central nervous system. By direct agonistic action on H₁receptors of the vessels of the inner ear, as well as indirectly through exposure to H₃-receptors improves microcirculation and permeability of capillaries, normalizes the pressure of the endolymph in the labyrinth and cochlea,increases blood flow in the basilar artery.

Has a pronounced central effect, being an inhibitor of H₃receptors of the nuclei of the vestibular nerve.

Improves conductivity in the neurons of the vestibular nuclei at the level of the brainstem. The clinical manifestation of these properties is a decrease in the frequency and intensity of dizziness, a decrease in tinnitus, an improvement hearing in case of its reduction.

Pharmacokinetics:

Absorbed quickly, the connection with plasma proteins is low. The time required to reach the maximum concentration is 3 hours. It is almost completely excreted by the kidneys in the form of a metabolite (2-pyridylacetic acid) for 24 hours. The half-life period is 3-4 hours.

Indications:

- Treatment and prevention of vestibular vertigo of various etiologies;

- fromindroma, including dizziness and headache, tinnitus, progressive hearing loss, nausea, vomiting;

- bDisease and Meniere's syndrome.

Contraindications:

Hypersensitivity to any of the components of the drug, lactose intolerance, lactase deficiency or glucose-galactose malabsorption, children under 18 years (due to lack of data), pregnancy and lactation (due to lack of data).

Carefully:

Peptic ulcer of stomach or duodenum (in the anamnesis), pheochromocytoma, bronchial asthma.

These patients should be observed regularly during the treatment period.

Pregnancy and lactation:

There is insufficient data to assess the effects of the drug during pregnancy and lactation. In this regard, not recommended during pregnancy. For the duration of treatment it is necessary to stop breastfeeding.

Dosing and Administration:

Inside, with food, ¹/₂-1 tablets 3 times a day.

Improvement is usually noted already at the beginning of therapy, a stable therapeutic effect occurs after two weeks of treatment and may increase over several months of treatment. Treatment is long. The course of treatment is determined individually.

Side effects:

Gastrointestinal disorders, allergic reactions from the skin (skin rash, itching, urticaria), Quincke's edema.

Overdose:

Symptoms: nausea, vomiting, convulsions.

Treatment: gastric lavage, intake of activated charcoal, symptomatic therapy.

Interaction:

Cases of interaction or incompatibility with other drugs are unknown.

Effect on the ability to drive transp. cf. and fur:

Betagistin has no sedative effect and does not affect the ability to drive a car or engage in activities requiring rapidity of psychomotor reactions.

Form release / dosage:

Tablets, 16 mg.

Packaging:

10 tablets are placed in a contour mesh package made of a polyvinyl chloride light barrier film and aluminum foil.

For 2, 3 or 5 contour mesh packages together with the instruction for use are placed in a pack of cardboard.

Storage conditions:

In a dry, the dark place at a temperature of no higher than 25 ° C.

Keep out of the reach of children.

Shelf life:

2 years.

Do not use after the expiration date printed on the package.

Terms of leave from pharmacies:On prescription

Registration number:LSR-003585/10

Date of registration:29.04.2010

Expiration Date:Unlimited

The owner of the registration certificate:MOSHIMFARM PREPARATES them. N.А.Semashko, OJSC MOSHIMFARM PREPARATES them. N.А.Semashko, OJSC Russia

Manufacturer: & nbsp

MOSHIMFARM PREPARATES them. NA Semashko OJSC Russia

Representation: & nbspMOSHIMFARM PREPARATES them. NA Semashko OJSC MOSHIMFARM PREPARATES them. NA Semashko OJSC Russia

Information update date: & nbsp24.01.2017

Illustrated instructions

Instructions

Betagistin (Betahistine)