Active substanceBifidobacteria bifidumBifidobacteria bifidum
Similar drugsTo uncover
  • Bifidumbacterin
    suppositories rect. the vagina. 
    PARTNER, CJSC     Russia
  • Bifidumbacterin
    lyophilizate locally inwards 
  • Bifidumbacterin
    lyophilizate locally inwards 
  • Bifidumbacterin
    suppositories rect. the vagina. 
  • Bifidumbacterin
    capsules inwards 
    EKOPOLIS, ZAO     Russia
  • Bifidumbacterin
    lyophilizate locally inwards 
    EKOPOLIS, ZAO     Russia
  • Bifidumbacterin
    lyophilizate inwards locally 
  • Bifidumbacterin dry
    lyophilizate locally inwards 
  • Bifidumbacterin forte®
    capsules inwards 
    PARTNER, CJSC     Russia
  • Bifidumbacterin, suppositories
    suppositories rect. the vagina. 
  • Bifinorm
    lyophilizate locally inwards 
  • Dosage form: & nbspcapsules
    Composition:

    One capsule contains live bifidobacteria not less than 5x107; Excipients - lactose or lactulose - 17.5%.

    Capsule shell composition: body - titanium dioxide 2%, gelatin (formative) up to 100%; cap gelatin (formative) - up to 100%, indigo carmine - 0.1333%.

    Description:

    Hard gelatin capsules No. 3, cylindrical with hemispherical ends; the case is white; capsule cover is blue. The contents of the capsule are a beige or whitish-gray powder with a specific odor.

    Pharmacotherapeutic group:Eubiotic
    ATX: & nbsp

    A.07.F.A   Antidiarrhoeal preparations of biological origin regulating the balance of intestinal microflora

    Pharmacodynamics:

    The preparation is a microbial mass of living, antagonistically active strains Bifidobacterium bifidum No. 1 or 791 lyophilized and packaged in capsules and used as a medicine.

    The therapeutic effect of bifidumbacterin in capsules determines the living bifidobacteria contained in it, which have antagonistic activity against a wide range of pathogenic and conditionally pathogenic microorganisms and thereby normalize the intestinal and vaginal microflora. The high quantitative level of bifidoflora and its predominance in the microbiocenosis, achieved with the use of bifidumbacterin in capsules,normalizes the activity of the gastrointestinal tract, improves metabolic processes, prevents the formation of protracted forms of intestinal diseases, increases the nonspecific resistance of the organism. Oral administration of the most bifidumbacterin in capsules makes it possible to increase the bioavailability of the drug and thereby enhance the therapeutic effect of bifidobacteria.

    Appointment

    The drug is intended for the treatment of acute and chronic gastrointestinal diseases, accompanied by dysbiosis in children and adults. Children (including premature) drug can be used from the first days of life.

    In obstetric-gynecological practice - locally (in the form of a solution of the contents of the capsule), for the prevention and treatment of mastitis and dysbiosis of the vagina.

    Indications:

    With diseases of the gastrointestinal tract:

    - for the treatment of long-term intestinal dysfunctions not established etiology;

    - with acute intestinal infections (in the complex treatment of acute dysentery, salmonellosis, escherichiosis, viral diarrhea, etc.), long-term intestinal dysfunctions of staphylococcal etiology, and treatment of convalescent cells after acute intestinal infections with continuing intestinal dysfunction;

    - in complex treatment of children (including newborns, prematurity), patients with pneumonia, sepsis and other purulent-infectious diseases for preventing or stopping their bowel function disorders and preventing the development of ulcerative-necrotic enterocolitis;

    - for the treatment and prevention of dysbacteriosis in children with a burdened premorbid condition, prematurely born or with signs of prematurity receiving antibiotics in the early neonatal period; children whose mothers suffered from severe toxicosis, extragenital diseases, had a long anhydrous period or other pathology; children of mothers who had lactostasis, nipple cracking and resuming breastfeeding after recovery from mastitis; weakened children with anemia, hypotrophy, rickets, diathesis and other manifestations of allergy; with pertussis disease accompanied by intestinal bowel disorders;

    - with early transfer of infants to artificial feeding or feeding with donor milk;

    - for the treatment of acute and chronic inflammatory diseases of the large and small intestine (colitis,enterocolitis) in older children and adults that occur against a background of microflora disorders with deficiency or lack of bifidoflora;

    - with intestinal dysfunctions as a result of dysbacteriosis of the intestine, which arose as a result of prolonged antibacterial, hormonal, radiation and other therapy, stay in extreme conditions, and with the goal of preventing dysbiosis in these individuals.

    In obstetrics and gynecology practice (as a solution of the contents of the capsule):

    - for the purpose of preventing mastitis for local treatment of the mammary glands of nursing mothers of the "risk" group (in women with a retracted flat nipple, with a decrease in its erection, the presence of cracks) with an aggravated epidemiological situation in maternity hospitals;

    - if the purity of the vaginal secretion is breached III-IV degree in the pregnant "risk" group;

    - with bacterial colpitis caused by staphylococcus and E. coli (in monoflora or in associations), as well as senile colpitis of hormonal nature.

    Contraindications:There were no reactions to the drug administration.
    Pregnancy and lactation:

    Bifidobacteria are representatives of normal human microflora, therefore, preparations made on their basis, can be used during pregnancy and lactation.

    Dosing and Administration:

    1.Treatment and prevention of gastrointestinal diseases.

    The preparation "Bifidumbacterin capsules" is applied through the mouth by swallowing whole capsules with a sufficient amount of liquid at room temperature or by ingesting a slurry obtained by dissolving the contents of the opened capsule in a small amount of cooled boiled water. When dissolved in water, it forms an opaque slurry having a specific acid-milk smell and taste. It is inadmissible to dissolve the preparation with hot water and store it in a dissolved form.

    Children under three years of age should not be given whole capsules to avoid getting them into the respiratory tract - it is necessary to use the preparation in the form of a solution.

    The drug is taken 20-30 minutes before meals or 1-1,5 hours after taking food.

    Breast children can be given the drug immediately before feeding.

    In acute intestinal diseases for children of the first year of life, the drug is prescribed 5 doses (the contents of one capsule) for taking 2 times a day. Children older than 1 year - 5 doses (the contents of one capsule) 3 times a day.

    With sepsis, pneumonia and other purulent-septic diseases, children are prescribed 5 doses 3 times a day in combination withgenerally accepted methods of treatment of the underlying disease. If this group of children has a function disorder gastrointestinal tract and threat of ulcerative-necrotic enterocolitis, the dosage of bifidumbacterin is increased to 20 doses per day.

    Newborns of the "risk" group should start using the drug in the maternity department from the first day of life to discharge 2.5 doses per reception 2 times a day. The contents of 1 capsule are dissolved in a small amount of boiled water or milk.

    Method of dissolution. In clean dishes, pour the contents of one capsule (gently separating the capsule cover from the body of the capsule) and add cooled boiled water. 1 teaspoon per dose of the drug, mixed until a homogeneous suspension of whitish gray or different shades of beige. One teaspoon of the solution thus prepared is one dose.

    Attention! To prepare the drug solution, especially for young children, Use only clean cookware. The solution of the drug is not subject to storage.

    Children older than 3 years and adults with acute and chronic inflammatory diseases of the small and large intestine (enterocolitis and colitis)It is recommended to take 1 capsule (5 doses) 2-3 times a day. In severe cases, the dose can be doubled.

    The duration of treatment with bifidumbacterin in capsules is determined by the severity of clinical manifestations, the patient's age and is 2-4 weeks, and in some cases up to 3 months.

    With the preventive purpose, the drug is prescribed 1 capsule (5 doses) 1-2 times a day for 1-2 weeks.

    2. In obstetrics and gynecology practice the preparation is applied topically in the form of a solution of the contents of the capsule.

    To treat the area of ​​the nipple and areola at the puerperas, the contents of 1 capsule are dissolved in a small amount of boiled water, impregnated with a solution of 2 sterile swabs that are applied to the nipple and areola 20-30 minutes before feeding for 5 days. The tampon impregnated with the drug is left on the surface of the mammary gland before the beginning of the feeding.

    For inflammatory diseases of the female genitalia and prenatal preparation of the pregnant "risk" group, a drug in the form of a solution for impregnating a tampon or syringes is prescribed for 5-10 doses (1-2 capsules) once a day for 5-8 days under the control of purity of the vaginal secret to the I-II degree and disappearanceclinical symptoms of the disease.

    For intravaginal administration, bifidumbacterin is also dissolved by this method. The resulting suspension of the preparation is impregnated with a sterile swab, which is administered intravaginally and left for 2-3 hours.

    If necessary, the course of treatment with bifidumbacterin can be repeated.

    Side effects:

    Not identified.

    Interaction:

    Clinically significant interaction of the drug with other drugs has not been established.

    Bifidumbacterin can be used simultaneously with antibacterial, antiviral and immunomodulatory therapy.

    Corrective therapy with bifidumbacterin can be prescribed after treatment with specific bacteriophages designed to eliminate opportunistic bacteria.

    Special instructions:

    The drug contains lactose - should be administered with caution to persons with lactase deficiency.

    Effect on the ability to drive transp. cf. and fur:The drug does not affect the performance of activities requiring special attention and quick reactions (management of vehicles, machinery, etc.).
    Form release / dosage:Capsules, 5 doses.
    Packaging:

    10, 20, 30, 40, 50 capsules in a polypropylene polymer can.

    One bank in a pack of cardboard with instructions for use.

    Storage conditions:

    The preparation is stored in accordance with JV 3.3.2. 1248-03. at a temperature not exceeding 10 ° C, out of the reach of children.

    Transport conditions:

    Transportation is carried out in accordance with SP 3.3.2. 1248-03. at a temperature not exceeding 10 ° C.

    Not suitable for use:

    - a drug whose integrity of packaging is broken (the jar is cracked or the control of the first autopsy is broken), the drug without labeling;

    - a drug with expired shelf life or in case of its storage with non-compliance with the relevant conditions.

    Shelf life:

    2 years.

    Terms of leave from pharmacies:Without recipe
    Registration number:P N002220 / 01
    Date of registration:09.06.2008
    Expiration Date:Unlimited
    The owner of the registration certificate:EKOPOLIS, ZAO EKOPOLIS, ZAO Russia
    Manufacturer: & nbsp
    Information update date: & nbsp14.02.2017
    Illustrated instructions
      Instructions
      Up