From the cardiovascular system:
often: peripheral edema, increased blood pressure, including weighting the course of arterial hypertension;
infrequently: "hot flashes", a feeling of palpitations;
rarely: chronic heart failure, arrhythmia, tachycardia, ischemic stroke and myocardial infarction.
From the digestive system:
often: abdominal pain, diarrhea, indigestion, flatulence, vomiting;
infrequently: dental disease (postextraction lune alveolitis);
rarely: gastric and duodenal ulcers, ulceration of the esophagus;
very rarely: intestinal perforation, pancreatitis.
From the nervous system:
often: dizziness, insomnia;
infrequently: anxiety, increased muscle tone, snotty;
rarely: confusion (psychosis).
From the urinary system:
often: urinary tract infection.
From the respiratory system:
often: bronchitis, cough, sinusitis, infections of the upper respiratory tract;
infrequently: pharyngitis, rhinitis.
From the skin:
often: itchy skin (including generalized), skin rash;
infrequently: urticaria, ecchymosis;
rarely: alopecia.
From the hematopoiesis:
infrequently: anemia;
pedko: thrombocytopenia.
From the sense organs:
infrequently: noise in the ears, blurred vision.
Laboratory indicators:
infrequently: increased activity of "hepatic" enzymes (including alanine aminotransferase and aspartate aminotransferase).
Allergic reactions:
rarely: angioedema;
very rarely: bullous eruptions (bullous dermatitis).
Other:
infrequently: exacerbation of allergic diseases (hypersensitivity), flu-like syndrome, accidental trauma, edema of the linden.
According to post-marketing surveillance data
Allergic reactions:
very rarely: anaphylaxis (anaphylactic reactions).
From the nervous system:
rarely: hallucinations;
very rarely: cerebral hemorrhage, aseptic meningitis, loss of taste
sensations, loss of smell.
From the sense organs:
infrequently: conjunctivitis.
From the cardiovascular system:
rarely: thromboembolism of the pulmonary arteries;
very rarely: vasculitis.
From the digestive system:
rarely: gastrointestinal bleeding, hepatitis;
very rarely: hepatic insufficiency, fulminant hepatitis, liver necrosis (see section "Special instructions", subsection "Influence on liver function"), cholestasis, cholestatic hepatitis, jaundice.
From the skin:
pedko: photosensitivity reaction;
very rarely: Stevens-Johnson syndrome, erythema multiforme, toxic epidermal necrolysis, drug rash in combination with eosinophilia and systemic symptoms (DRESS or hypersensitivity syndrome), acute generalized exanthematous pustulosis, exfoliative dermatitis.
From the urinary system:
rarely: acute renal failure (see section "Special instructions", subsection
"Influence on the function of the nights"), hyponatremia;
very rarely: interstitial nephritis, nephrotic syndrome, minimal renal dysfunction.
On the part of the reproductive system:
rarely: violation of the menstrual cycle:
frequency unknown: decreased fertility in women * (see "Pregnancy and Breastfeeding").
Other:
infrequently: chest pain.
* Women planning pregnancy were excluded from the study, so they were not taken into account when calculating the frequency of occurrence.