Disol (Disol)

Composition Pharmacodynamics Indications Carefully Contraindications Dosing and Administration Side effects Form release / dosage
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Active substanceSodium acetate + Sodium chlorideSodium acetate + Sodium chloride
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    • Dosage form: & nbspsolution for infusions
    Composition:

    Active substances:

    Sodium chloride ...............................6 grams

    Sodium acetate ....................................... 2 grams
    (sodium acetate, 3-water)

    Excipient:

    Water for injections.......................up to 1l

    Description:Transparent colorless liquid.
    Pharmacotherapeutic group:rehydrating agent
    ATX: & nbsp

    B.05.B.B.01   Electrolytes

    Pharmacodynamics:Combined saline solution for rehydration and detoxification. It restores the water-electrolyte balance and acid-base state in the body during dehydration. Prevents the development of metabolic acidosis, increases diuresis. Provides plazmozameschayuschee, detoxification, rehydrating effect.
    Indications:Rehydration, hyperkalemia, intoxication on the background of dehydration (cholera, acute dysentery, food toxicoinfection).
    Contraindications:Hypersensitivity, renal and chronic heart failure.
    Carefully:With caution, the drug should be used in patients with impaired renal excretory function, with hypokalemia.
    Pregnancy and lactation:

    The use of the drug during pregnancy and lactation is possible only in the event that, when the intended use for the mother exceeds the potential risk to the fetus (adekand strictly controlled studies have not been carried out).

    Dosing and Administration:

    Intravenously (struino and drip), under the control of laboratory indicators. The ratio of the injected liquid and diuresis is determined every 6 hours. Within 1 hour, the solution is administered in an amount corresponding to 7-10% of the body weight of the patient; then the jet infusion is replaced by a dropwise addition, for 24-48 hours, at a rate of 40-120 cap / min. Before administration, the solution is heated to 36-38 C. The solution is administered in amounts necessary to restore the volume of fluid lost with feces, vomit, urine, sweat.

    In severe forms of diseases (hypovolemic infectious-toxic shock, decompensated metabolic acidosis, anuria) begin with a jet injection with the subsequent transition to a drop.

    With lighter forms of diseases (intoxication and dehydration of the body, metabolic acidosis, oliguria), you can limit the drip introduction of the drug.

    After elimination of hyperkalemia, further water-salt therapy is carried out in solutionRami "Trisol", "Acesol" or "Khlosol".

    Side effects:Edema, tachycardia. In some cases, chills may occur.
    Overdose:

    Symptoms: hypokalemia, hypernatremia.

    Treatment: correction of electrolyte disorders; control of the level of electrolytes in the blood.

    Interaction:Not installed
    Special instructions:

    Therapy is carried out under the control of hematocrit and the concentration of blood electrolytes.

    Effect on the ability to drive transp. cf. and fur:Data are not available due to the use of the drug exclusively in the hospital.
    Form release / dosage:

    Solution for infusion.

    200 ml or 400 ml in a glass bottle, sealed with a rubber stopper and crimped with an aluminum cap. 250 ml or 500 ml in a polymer container.The bottle together with the instruction for use is placed in a pack of cardboard, the polymer container is packed in a secondary bag made of polyethylene or polyethylene polyamide film or in a pack of cardboard.

    24 bottles of 200 ml or 12 bottles of 400 ml or 24 polymer containers of 250 ml or 12 polymer containers of 500 ml with an equal number of instructions for use are placed in a group package - boxes of corrugated cardboard (with gaskets and lattices for bottles).
    Packaging:
    Storage conditions:

    At a temperature below 25 ° C.

    Keep out of the reach of children.

    Freezing the drug is not a contraindication to its use.

    Non-wetting of the inner surface of the bottle (polymer container) is not a contraindication to the use of the drug.

    Shelf life:

    2 years. Do not use after the expiration date.

    Terms of leave from pharmacies:On prescription
    Registration number:P N003712 / 01
    Date of registration:18.05.2009
    The owner of the registration certificate:BIOSINTEZ, PAO BIOSINTEZ, PAO Russia
    Manufacturer: & nbsp
    Information update date: & nbsp11.07.2012
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