Disol (Disol)

Composition Pharmacodynamics Indications Carefully Contraindications Dosing and Administration Side effects Form release / dosage
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Active substanceSodium acetate + Sodium chlorideSodium acetate + Sodium chloride
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    • Dosage form: & nbspsolution for infusions
    Composition:

    1 liter of the drug contains:

    Active substances:

    Sodium chloride ..................................... 6.0 g

    Sodium acetate trihydrate.................2.0 g

    Excipient:

    Water for injections ........................up to 1 liter

    Ionic composition for 1 l:
    Sodium ion....................... 117.4 mmol

    Chloride ion ....................... 102.7 mmol

    Acetate ion ......................... 14.7 mmol

    Theoretical osmolarity 235 mOsm / l

    Description:

    Transparent colorless liquid.

    Pharmacotherapeutic group:Rehydrating agent.
    ATX: & nbsp

    B.05.B.B.01   Electrolytes

    Pharmacodynamics:

    Combined saline solution for rehydration and detoxification. It restores the water-electrolyte balance and acid-base state in the body during dehydration. Prevents the development of metabolic acidosis, increases diuresis. Provides plazmozameschayuschee, detoxification, rehydrating effect.

    Pharmacokinetics:

    It is excreted by the kidneys.

    Indications:

    Dehydration, hyperkalemia, intoxication on the background of dehydration (cholera, acute dysentery, food toxicoinfection).

    Contraindications:

    Renal and heart failure.

    Carefully:

    With caution, the drug should be used for hypokalemia.

    Pregnancy and lactation:

    The use of the drug during pregnancy is possible only if the intended benefit to the mother exceeds the potential risk to the fetus. It should refrain from breastfeeding during the period of use of the drug because of the lack of relevant clinical data.

    Dosing and Administration:

    Intravenously (struyno and drip), under the control of laboratory indicators (electrolytes Na+, TO+, SG, acid-base blood state). The ratio of the injected liquid and diuresis is determined every 6 hours. Within 1 hour, injections are introduced, then the jet infusion is replaced by a dropwise addition, for 24-48 hours, at a rate of 40-120 cap / min. Before administration, the solution is heated to 36-38 ° C. The solution is administered in amounts necessary to restore the volume of fluid lost with feces, vomit, urine, sweat.

    In severe forms of diseases (hypovolemic infectious-toxic shock, decompensated metabolic acidosis, anuria) begin with a jet injection of the drug followed by a transition to a drop.

    With lighter forms of diseases (intoxication and dehydration of the body, metabolic acidosis, oliguria), you can restrict the drip administration of the drug. After elimination of hyperkalemia, further water-salt therapy is carried out with solutions of Trisol, Acesol or Chlosol.

    Side effects:

    Edema, tachycardia. In some cases, chills may occur.

    Overdose:

    Symptoms: hypokalemia, hypernatremia.
    Treatment: correction of electrolyte disorders; control of the level of electrolytes in the blood.

    Interaction:

    When combined with other drugs, it is necessary to visually control the pharmaceutical incompatibility.

    Special instructions:

    Therapy is carried out under the control of hematocrit and the concentration of blood electrolytes.

    In general, with dehydration, oral solutions for oral rehydration are indicated, and only when disinfection is impossible (for one reason or another), Disol is administered.

    Effect on the ability to drive transp. cf.and fur:

    It was not reported on the effect of the drug on psychophysiological reactions and the ability to control vehicles and mechanisms.

    Form release / dosage:

    Solution for infusion.

    For 100, 200, 250, 400, 500 or 1000 ml in polypropylene bottles, sealed with welded polypropylene caps.

    One bottle together with instructions for use in a pack of cardboard.

    For hospitals

    From 1 to 40 vials of 100, 200, 250, 400, 500 or 1000 ml together with instructions for use in an amount equal to the number of vials in a corrugated box of cardboard.

    Packaging:1-40 bottles, polypropylene bottles (1) -Cartboard boxes
    bottles made of polypropylene (1), cardboard
    Storage conditions:

    Store at a temperature not exceeding 25 ° C.

    Keep out of the reach of children.

    Shelf life:

    2 years.

    Do not use after the expiration date!

    Terms of leave from pharmacies:On prescription
    Registration number:LP-002713
    Date of registration:14.11.2014
    The owner of the registration certificate:GROTEKS, LLC GROTEKS, LLC Russia
    Manufacturer: & nbsp
    Information update date: & nbsp14.11.2014
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