From the side of the organ of vision: blurred vision, blepharitis, cataracts, conjunctivitis, allergic lesions of the conjunctiva (including follicles, conjunctival papillary reactions, pinpoint hemorrhages, etc.), cornea lesions (erosion, pigmentation, spot keratitis, etc.), refractive disorders, hyperemia of the eye , eye irritation, eye pain, increased pigmentation of the iris, keratitis, photophobia, loss of fields of vision.
Infections: sinusitis, upper respiratory tract infections and other infections.
Metabolic and nutritional disorders: diabetes mellitus, hypercholesterolemia.
Mental disorders: depression.
From the nervous system: headache.
Vascular disorders: increase in blood pressure.
From the skin and subcutaneous tissues: hypertrichosis, rash and skin changes (irritation, chalazion, etc.).
From the side of the musculoskeletal system and connective tissue: arthritis.
The following are other undesirable effects that may occur with therapy with certain Duoprost components (apart from the above).
Latanoprost:
From the side of the organ of vision: irritation of the eyes (burning sensation, sensation of sand in the eyes, itching,tingling and sensation of foreign body); transient point erosions of the epithelium, edema of the eyelids, edema and erosion of the cornea; lengthening, thickening, increasing the number and increasing pigmentation of eyelashes and gun hair; iritis / uveitis; macular edema, incl. cystoid; changing the direction of growth of eyelashes, sometimes causing eye irritation; blurred vision.
From the skin and subcutaneous tissues: skin rash, darkening of the skin of the eyelids and local skin reactions on the eyelids.
From the nervous system: dizziness.
On the part of the respiratory system: bronchospasm (including acute attacks or exacerbation of the disease in patients with bronchial asthma in the anamnesis), dyspnea.
From the side of the musculoskeletal system and connective tissue: pain in the muscles / joints.
General and local reactions: nonspecific pain in the chest.
Timolol (in the form of eye drops):
From the immune system: systemic allergic reactions, incl. anaphylaxis, angioedema, urticaria, localized and generalized rash.
Metabolic and nutritional disorders: anorexia, latent symptoms of hypoglycemia in patients with diabetes mellitus.
Mental disorders: behavioral changes and mental disorders, incl. confusion, hallucinations, anxiety, disorientation, nervousness, memory loss, decreased libido, insomnia and nightmares.
From the nervous system: cerebral ischemia, acute disorders of cerebral circulation, dizziness, increased symptoms of myasthenia gravis gravis, paresthesia, drowsiness, fainting.
From the side of the organ of vision: cystoid macular edema, decreased sensitivity of the cornea; abruption of the choroid after filtration surgical interventions; ptosis, visual impairment, incl. change refraction and diplopia.
From the side of the hearing and vestibular organs: noise in ears.
From the heart: arrhythmia, bradycardia, cardiac arrest, heart failure, blockade of intracardiac conduction, palpitation, progression of angina pectoris.
Vascular disorders: intermittent claudication, coldness of the hands and feet, lowering blood pressure, Raynaud's syndrome.
On the part of the respiratory system: bronchospasm (mainly in patients with previous bronchospastic diseases), cough, shortness of breath, nasal congestion, pulmonary edema and respiratory failure.
From the gastrointestinal tract: diarrhea, dry mouth, dyspepsia, nausea, retroperitoneal fibrosis.
From the skin and subcutaneous tissues: alopecia, pseudo-pemphigoid, psoriasis-like rash or exacerbation of psoriasis.
From the side of the musculoskeletal system and connective tissue: systemic lupus erythematosus.
On the part of the reproductive system and mammary glands: impotence, Peyronie's disease.
General and local: asthenia / fatigue, chest pain, swelling.