Essential phospholipids are the main elements of the structure of the cell membrane and cellular organelles. In diseases of the liver, there is always damage to the membranes of the liver cells and their organelles, which leads to disturbances in the activity of the enzymes and receptor systems associated with them, impairment of the functional activity of the hepatic cells, and a decrease in the ability to regenerate.
Phospholipids, which are part of the Essentnale H preparation, correspond in their chemical structure to endogenous phospholipids, but exceed the endogenous phospholipids by activity due to a higher content of polyunsaturated (essential) fatty acids. The incorporation of these highly energetic molecules into the damaged sections of the cell membranes of hepatocytes restores the integrity of the hepatic cells, promotes their regeneration. Cis-double bonds of their polyunsaturated fatty acids prevent the parallel arrangement of hydrocarbon chains in the phospholipids of cell membranes, the phospholipid structure of the cellular envelopes of hepatocytes "loosens", which causes an increase in their fluidity and elasticity, improves metabolism.The resulting functional blocks increase the activity of enzymes fixed on the membranes and promote the normal, physiological pathway of the most important metabolic processes. Phospholipids, which are part of Essential H, regulate the metabolism of lipoproteins, transferring neutral fats and cholesterol to oxidation sites, mainly by increasing the ability of high-density lipoproteins to bind to cholesterol.
Thus, there is a normalizing effect on the metabolism of lipids and proteins; on the detoxification function of the liver; on the restoration and preservation of the cellular structure of the liver and phospholipid-dependent enzyme systems; which ultimately prevents the formation of connective tissue in the liver.
In the excretion of phospholipids in bile there is a decrease in the lithogenic index and stabilization of bile.