Intravenous (dropwise, at a speed of 40-50 cap / min, dissolving in 250-300 ml of 5% dextrose solution, or in / in struyno, pre-dilute the patient's blood in a 1: 1 ratio), 1-2 ampoules (5-10 ml ) per day or in severe cases 2-4 ampoules (10-20 ml) per day. As the patient's condition improves, parenteral administration is replaced as soon as possible by oral administration of the drug. The course of treatment - 3 months, if necessary, can be continued or repeated.
Treatment of psoriasis begins with a 2-week capsule intake (600 mg 3 times a day), then 10 intravenous infusions of 250 mg daily are administered and simultaneously PUVA therapy begins. After completion of the infusion, the capsules are resumed for 2 months.In the presence of contraindications to PUVA-therapy are limited to the use of the drug according to the above procedure, incl. in combination with conventional methods of treatment of psoriasis.
Do not dilute the drug with electrolyte solutions (0.9% solution of sodium chloride, Ringer's solution)!