Active substancePhospholipidsPhospholipids
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  • Dosage form: & nbspsolution for intravenous administration
    Composition:

    for 5 ml:

    active substance: Essential phospholipids of soybeans (soybean phospholipids) 357.2 mg containing 70% (3 -sn-phosphatidyl) choline, in terms of (3-sn- phosphatidyl) choline 250 mg;

    Excipients: Gasoline alcohol, riboflavin, propylene glycol, butyl-hydroxytoluene, butylhydroxyanisole, alpha-tocopherol acetate (vitamin E), sodium deoxycholate, water for injection

    Description:

    Transparent liquid of yellow color.

    Pharmacotherapeutic group:Hepatoprotective agent
    ATX: & nbsp

    A.05.C   Combination of drugs for the treatment of diseases of the liver and biliary tract

    Pharmacodynamics:

    Hepatoprotective agent; included in phospholipids are the main elements in the structure of the cell membrane and mitochondria. Regulates lipid and carbohydrate exchange, improves the functional state of the liver and its detoxification function, contributes to the preservation and restoration of the structure of hepatocytes; inhibits the formation of connective tissue in the liver.

    Pharmacokinetics:

    No pharmacokinetics studies have been performed.

    Indications:

    In the combined therapy: hepatitis (acute and chronic), fatty liver of various genesis (diabetes, chronic infections), chronic hepatitis (including officinale), alcoholic hepatitis, liver cirrhosis, hepatic coma, gestosis, radiation sickness, psoriasis, impaired liver function in other somatic diseases.

    Contraindications:

    Hypersensitivity, children under 18 years.

    Carefully:

    Pregnancy and lactation (due to the presence of benzyl alcohol). Required To treat the solution for intravenous administration with only a short course with a further transition to oral administration.

    Dosing and Administration:

    Intravenous (preferably dropwise, at a rate of 40-50 drops / min by dissolving in 250-300 ml 5% dextrose solution, or in / jet, previously diluted blood of the patient in a ratio of 1: 1), 0.5-1 g 2-3 times a day.At the beginning of treatment, it is desirable to combine parenteral administration with oral administration, as the patient's condition improves, the treatment is continued with capsules. The course of treatment - 3 months, if necessary, can be continued or repeated.

    Treatment of psoriasis begins with a 2-week capsule intake (600 mg 3 times a day), then 10 intravenous infusions of 250 mg daily are administered and simultaneously PUVA therapy begins. After completing the infusion, the capsules are resumed for 2 months. In the presence of contraindications to PUVA-therapy are limited to the use of the drug according to the above procedure, incl. in combination with conventional methods of treatment of psoriasis.

    Do not dilute the drug with electrolyte solutions (0.9% solution of sodium chloride, Ringer's solution)!

    Side effects:

    Nausea, gastralgia, allergic reactions (skin rash, itching, urticaria), incl. because of the presence of benzyl alcohol.

    Overdose:

    No cases of overdose have been reported.

    Interaction:

    Pharmaceutically incompatible with solutions of electrolytes.

    Special instructions:

    Parenteral only enter clear solutions.

    Form release / dosage:

    Solution for intravenous administration, 50 mg / ml


    Packaging:For 5 ml of the drug in ampoules brown glass I hydrolytic class, 5 ampoules in a plastic pallet with instructions for use in a cardboard pack.
    Storage conditions:

    In the dark place at a temperature of 2 to 8 ° C.

    Keep out of the reach of children.

    Shelf life:

    3 years.

    Do not use the drug after the expiration date.

    Terms of leave from pharmacies:On prescription
    Registration number:LSR-005424/10
    Date of registration:10.06.2010
    The owner of the registration certificate:Outline Pharma Pvt. Ltd.Outline Pharma Pvt. Ltd. India
    Manufacturer: & nbsp
    Information update date: & nbsp29.10.2015
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