Phosphontsiale - instructions for use, doses, side effects, contraindications

Excipients: silicon dioxide colloid (aeroprel 300), povidone (kollidon 90 E), calcium phosphate dihydrate, magnesium with the therapeut, tricalose dihydrate; Helps capsule shell accessories: gelatin, titanium dioxide, sunset yellow.

Description:

Capsules of gelatinous light-orange color, № 0.

Contents of capsules: a loose mass of a yellowish brown color with a specific odor (individual agglomerates coalesce in a dense mass with light compression).

Pharmacotherapeutic group:Hepatoprotective agent

ATX: & nbsp

A.05.C Combination of drugs for the treatment of diseases of the liver and biliary tract

Pharmacodynamics:

Combined drug for the treatment of diseases of the liver and biliary tract. Reproduces clinico-pharmacological effects of the components contained in it - "essential" phospholipids and the sum of flavolignans (in terms of silibinin) thistle. Hepatoprotective agent, normalizes metabolism of lipids, proteins and phospholipids: stimulates protein synthesis; promotes the activation and protection of phospholipid-dependent enzyme systems, improves the functional state of the liver and its detoxification function, promotes the preservation and restoration of the structure of hepatocytes; inhibits the formation of connective tissue in the liver. Has a choleretic effect in cholestasis.

Indications:

In the complex therapy: chronic hepatitis of non-viral etiology; fatty degeneration of liver of various genesis; alcoholic hepatitis; cirrhosis of the liver, impaired liver function in other somatic diseases; psoriasis (ancillary therapy); violations of lipid metabolism,prevention of hepatic damage in chronic intoxication (long-term use of drugs, alcohol, work in harmful production).

Contraindications:

Hypersensitivity.

Carefully:

Assign patients with hormonal disorders (endometriosis, uterine fibroids, breast carcinoma, ovaries and uterus, carcinoma of the prostate gland) because of the possible appearance of an estrogen-like effect of silymar.

Pregnancy and lactation:

It is not recommended to use the drug during pregnancy and during breastfeeding.

Dosing and Administration:

The drug is used in adults on the recommendation of a doctor. Capsules are taken orally during meals, swallowing whole and with enough water. With chronic hepatitis of non-viral etiology, fatty liver dystrophy of various genesis and cirrhosis of the liver take 2 capsules 2-3 times at day. The course of treatment - at least 3 months (depending on the severity of the process). On the recommendation of a doctor, an increase in the duration of the drug or a repeat course is possible. In psoriasis, as an auxiliary therapy, the drug is taken 1-2 capsules 3 times a day, the course of treatment is from 14 to 40 days. The duration of the drug is determined by the doctor.If there is a violation of the liver function, lipid metabolism disorders take 1-2 capsules 3 times a day.

The course of treatment is recommended by a doctor. For preventive purposes with chronic intoxication (including long-term use of drugs, alcohol, work in harmful production), the drug can be applied 1 capsule 2-3 times a day for 1-3 months. The duration of the drug is determined by the doctor.

Side effects:

Nausea, gastralgia, allergic reactions.

Overdose:

There is no evidence of an overdose of the drug. Treatment for accidental high-dose: induction of vomiting, gastric lavage, application activated charcoal, carrying out symptomatic therapy if necessary.

Interaction:

Since silymar has an inhibitory effect on the cytochrome P450 system, it is possible to increase the concentration in the blood plasma of such drugs as diazepam, alprazolam, ketoconazole, lovastine, vinblastine.

Special instructions:

Effect on the ability to drive transp. cf. and fur:The drug has no effect on the ability to perform potentially dangerous activities requiring increased concentration and speed of psychomotor reactions (controlmotor transport, work with moving mechanisms).

Form release / dosage:

Capsules.

Packaging:

For 10, 15 capsules in a contour cell pack of film polyvinylchloride and foil printed lacquered.

According to 3, 6 contour cell packs of 10 capsules or 2, 4 contourcell packs of 15 capsules together with instructions for use in a pack of cardboard

Storage conditions:

In dry, the dark place at a temperature of ns above 25 ° C. Keep out of the reach of children.

Shelf life:

2 years.

Do not use after the expiration date.

Terms of leave from pharmacies:On prescription

Registration number:LSR-006426/08

Date of registration:11.08.2008

The owner of the registration certificate:CANONFARMA PRODUCTION, CJSC CANONFARMA PRODUCTION, CJSC Russia

Manufacturer: & nbsp

CANONFARMA PRODUCTION, CJSC Russia

Representation: & nbspCANONFARMA PRODUCTION CJSC CANONFARMA PRODUCTION CJSC Russia

Information update date: & nbsp29.10.2015

Illustrated instructions

Instructions

Phosphontsiale® (Phosphonciale)