Active substanceNitrofuralNitrofural
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  • Dosage form: & nbspRAster for local and external use.
    Composition:

    Per 1 liter:

    active substance: nitrofural (furacilin) ​​- 0.2 g;

    Excipients: sodium chloride - 9.0 g; purified water - up to 1 liter.

    Description:Transparent liquid of yellow color, with a specific smell.
    Pharmacotherapeutic group:antimicrobial agent - nitrofuran
    ATX: & nbsp

    D.08.A.F.01   Nitrofural

    Pharmacodynamics:

    Antimicrobial agent, a derivative of nitrofuran. Bacterial flavoproteins, restoring the 5-nitro group, form highly reactive amino derivatives, which can cause conformational changes in proteins (including ribosomal) and other macromolecules, leading to the death of bacteria.

    It is active against Gram-positive and Gram-negative bacteria (Staphylococcus spp., Streptococcus spp., Escherichia coli, Clostridium perfringens).

    Sustainability develops slowly and does not reach a high degree.

    Pharmacokinetics:

    With external application, the absorption is insignificant. It penetrates through the histogematic barriers and is evenly distributed in liquids and tissues. The main pathway of metabolism is the reduction of the nitro group. It is excreted by the kidneys and partly with bile.

    Indications:

    Suppurative wounds, pressure sores, burns of II-III st., Minor skin lesions (including abrasions, scratches, cracks, cuts), tonsillitis, stomatitis, gingivitis.

    Contraindications:

    Hypersensitivity to the components of the drug, bleeding, allergic dermatosis.

    Carefully:

    Pronounced lesions of kidney function.

    Pregnancy and lactation:

    Application of pregnancy and lactation is possible if the expected benefit to the mother outweighs the potential risk to the fetus or child.

    Dosing and Administration:

    Outer, local.

    Irrigate wounds and impose a wet bandage.

    With tonsillitis, stomatitis, gingivitis - Rinse mouth and throat for 100 ml 2-3 times a day.

    Side effects:

    Allergic reactions, dermatitis, nausea, vomiting, anorexia, dizziness.

    Overdose:

    There is no information.

    Interaction:

    Incompatible with epinephrine (adrenaline), tetracaine, procaine (novocaine), resorcinol (resorcinol), and other reducing agents have been decomposed to form colored in pink or brownish color products.

    Incompatible with potassium permanganate, hydrogen peroxide and other oxidants oxidation due to the drug.

    Special instructions:

    Use of the drug by patients with severe burns on large surfaces: the kidney function may progression of renal failure (uremia, disruption of water-electrolyte balance, metabolic acidosis).

    Effect on the ability to drive transp. cf.and fur:

    Does not affect.

    Form release / dosage:

    Solution for local and external use, 0.02%.

    Packaging:

    To 100, 200, 400 ml bottles of dark glass, sealed with stoppers, stoppers with plastic or stoppers, plastic bottles or stoppers, stoppers, plastic bottles or stoppers, stoppers with plastic droppers and plastic caps or plastic or plastic caps or plastic or plastic lids closed with lids. lids or caps with plastic or ukuporennye means of closing polyethylene or polymeric.

    100, 200, 400 ml in polymer bottles filled with stoppers, stoppers with plastic or stoppers, plastic bottles or stoppers, stoppers with plastic drums or stoppers, stoppers with plastic droppers or stoppers, stoppers with plastic droppers and plastic caps or polymer caps or caps with plastic or plastic caps or polymeric or cap-lidded caps or plastic caps or ukuporennye means with the closing polyethylene or polymeric, or in bottles of polyethylene terephthalate ukuporenn with polymeric screw caps.

    For 100, 200, 400 ml in glass bottles corked with rubber stoppers and aluminum caps or in bottles, sealed with stoppers and polymer caps.

    Each bottle, a bottle together with the instruction for use, is placed in a pack of cardboard box for consumer packaging or in a bag made of polypropylene BOPP film or polyethylene film or polyethylene terephthalate film (for 200 and 400 ml polymer bottles).

    It is allowed to put the text of instructions for use on a pack, a label, on packages from a film of polypropylene, polyethylene and polyethylene terephthalate.

    It is allowed to lay bottles and bottles in a group box with a cardboard box from 6 to 60 pieces of 100, 200. 400 ml together with an equal number of instructions for use (for hospitals).

    Storage conditions:

    In the dark place at a temperature of no higher than 25 ° C.

    Keep out of the reach of children.

    Shelf life:

    2 years.

    Do not use after the expiration date indicated on the label.

    Terms of leave from pharmacies:Without recipe
    Registration number:LP-003974
    Date of registration:21.11.2016
    Expiration Date:21.11.2021
    The owner of the registration certificate:SAMARAHEDPROM, JSC SAMARAHEDPROM, JSC Russia
    Manufacturer: & nbsp
    Representation: & nbspSAMARAHEDPROM, JSCSAMARAHEDPROM, JSC
    Information update date: & nbsp15.12.2016
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