Furacilin - instructions for use, dose, side effects, contraindications

Antimicrobial agent, a derivative of nitrofuran. Bacterial flavoproteins, restoring the 5-nitro group, form highly reactive amino derivatives, which can cause conformational changes in proteins (including ribosomal) and other macromolecules, leading to the death of bacteria. It is active against gram-positive and gram-negative bacteria (incl. Staphylococcus spp., Streptococcus spp., Escherichia coli. Clostridium perfringens). Sustainability develops slowly and does not reach a high degree.

Pharmacokinetics:

With external and local application, the absorption is insignificant. It penetrates through the histogematic barriers and is evenly distributed in liquids and tissues. The main pathway of metabolism is the reduction of the nitro group. It is excreted by the kidneys and partly with bile.

Indications:

Outer: purulent wounds, pressure sores, burns I-III degree, minor damage to the skin (including abrasions, scratches, cracks, cuts). Locally: blepharitis, conjunctivitis, osteomyelitis,empyema of the paranasal sinuses and pleura; urinary tract infection - rinsing of cavities, acute tonsillitis, stomatitis, gingivitis.

Contraindications:

Hypersensitivity to nitrofural, nitrofuran derivatives and / or other components of the drug, bleeding, allergic dermatosis, marked renal dysfunction.

Pregnancy and lactation:

Application in pregnancy and during breastfeeding is possible if the intended benefit to the mother exceeds the potential risk to the fetus or child.

Dosing and Administration:

Outer, local.

A 0.02% aqueous solution of nitrofural is prepared immediately before use: 1 tablet (20 mg) is dissolved in 100 ml of distilled or boiled water. For faster dissolution, boiling or hot water. The solution is then cooled to room temperature.

Outer: water the wounds, impose moist bandages.

Locally: empyema of the paranasal sinuses (including with sinusitis) - rinsing of the cavity: osteomyelitis after the operation - rinsing the cavity followed by the application of a moist bandage; pleural empyema - after removal of pus, the pleural cavity is flushed and 20-100 ml of an aqueous solution is injected.To wash the urethra and bladder, an aqueous solution with an exposure of 20 minutes is used.

Blepharitis, conjunctivitis - instillation of an aqueous solution in a conjunctival sac. With tonsillitis, stomatitis, gingivitis - mouth and throat rinsing 100 ml 2-3 times a day. Duration of treatment - according to the indications depending on the nature and localization of the affected area.

Side effects:

Allergic reactions, dermatitis, skin itching.

If any of the side effects indicated in the manual are aggravated, or if you notice other side effects not listed in the instructions, tell your doctor.

Overdose:

No cases of overdose have been reported.

Interaction:

Not studied.

Special instructions:

Not studied.

Effect on the ability to drive transp. cf. and fur:

The use of the drug does not affect the ability to perform potentially dangerous activities requiring increased concentration and speed of psychomotor reactions (vehicle management, work with moving mechanisms, dispatcher and operator work).

Form release / dosage:

Tablets for solution for local and external use 20 mg.

Packaging:

For 10, 15, 20, 25 tablets in a contour mesh box made of PVC film and aluminum foil or in a contour non-cellular package of paper with a polyethylene coating.

By 20, 25, 30 tablets in cans of polymeric low-density polyethylene.

Each can of polymer or 1, 2, 3 contour packs together with the instruction for use is placed in a pack of cardboard.

It is allowed to pack 50, 100, 200, 400, 500 contour packs or 12. 12. 40, 50 polymer jars with an equal number of instructions for use in corrugated cardboard boxes (for hospitals).

Storage conditions:In a dry, protected from light place at a temperature of no higher than 25 ° C. Keep out of the reach of children.

Shelf life:5 years. Do not use the product after the expiration date printed on the package.

Terms of leave from pharmacies:Without recipe

Registration number:LP-004462

Date of registration:15.09.2017

Expiration Date:15.09.2022

The owner of the registration certificate:YUZHFARM, LLC YUZHFARM, LLC Russia

Manufacturer: & nbsp

YUZHFARM, LLC Russia

Information update date: & nbsp03.10.2017

Illustrated instructions

Instructions

Furacilin (Furacilin)